KEGG   Pan troglodytes (chimpanzee): 460535
Entry
460535            CDS       T01005                                 
Symbol
DHFR2
Name
(RefSeq) dihydrofolate reductase 2, mitochondrial
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00670  One carbon pool by folate
ptr00790  Folate biosynthesis
ptr01100  Metabolic pathways
ptr01240  Biosynthesis of cofactors
ptr01523  Antifolate resistance
ptr04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    460535 (DHFR2)
   00670 One carbon pool by folate
    460535 (DHFR2)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    460535 (DHFR2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    460535 (DHFR2)
Enzymes [BR:ptr01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     460535 (DHFR2)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 460535
NCBI-ProteinID: XP_001138522
Ensembl: ENSPTRG00000051799
VGNC: 1793
UniProt: A0A2I3TPN8
LinkDB
Position
2:complement(97328518..97333709)
AA seq 186 aa
MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS
IPEKNRPLNDRINLVLSRELKEPPQGAHFFARSLDDALKLTERPELANKVDMIWIVGGSS
VYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKF
EVYEND
NT seq 561 nt   +upstreamnt  +downstreamnt
atgtttcttttgctaaactgcatcgtcgctgtgtcccaaaacatgggcatcggcaagaac
ggggacctgcccaggccgccgctcaggaatgaattcaggtatttccagagaatgaccaca
acttcttcagtagagggtaaacagaatctggtgattatgggtaggaagacctggttctcc
attcctgagaagaatcgacctttaaatgatagaattaatttagttctcagcagagaactc
aaggaacctccacaaggagctcatttttttgccagaagtttggatgatgccttaaaactt
actgaacgaccagaattagcaaataaagtagacatgatttggatagttggtggcagttct
gtttataaggaagccatgaatcacctaggccatcttaaactatttgtgacaaggatcatg
caggactttgaaagtgacacgtttttttcagaaattgacttggagaaatataaacttctg
cctgaatacccaggtgttctctctgatgtccaggaggggaaacacatcaagtacaaattt
gaagtatatgagaatgattaa

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