Pan troglodytes (chimpanzee): 461435
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Entry
461435 CDS
T01005
Symbol
EGF
Name
(RefSeq) pro-epidermal growth factor isoform X5
KO
K04357
epidermal growth factor
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01521
EGFR tyrosine kinase inhibitor resistance
ptr04010
MAPK signaling pathway
ptr04012
ErbB signaling pathway
ptr04014
Ras signaling pathway
ptr04015
Rap1 signaling pathway
ptr04020
Calcium signaling pathway
ptr04066
HIF-1 signaling pathway
ptr04068
FoxO signaling pathway
ptr04072
Phospholipase D signaling pathway
ptr04151
PI3K-Akt signaling pathway
ptr04510
Focal adhesion
ptr04518
Integrin signaling
ptr04540
Gap junction
ptr04630
JAK-STAT signaling pathway
ptr04810
Regulation of actin cytoskeleton
ptr05160
Hepatitis C
ptr05165
Human papillomavirus infection
ptr05200
Pathways in cancer
ptr05207
Chemical carcinogenesis - receptor activation
ptr05208
Chemical carcinogenesis - reactive oxygen species
ptr05210
Colorectal cancer
ptr05212
Pancreatic cancer
ptr05213
Endometrial cancer
ptr05214
Glioma
ptr05215
Prostate cancer
ptr05218
Melanoma
ptr05219
Bladder cancer
ptr05223
Non-small cell lung cancer
ptr05224
Breast cancer
ptr05226
Gastric cancer
ptr05231
Choline metabolism in cancer
ptr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
461435 (EGF)
04012 ErbB signaling pathway
461435 (EGF)
04014 Ras signaling pathway
461435 (EGF)
04015 Rap1 signaling pathway
461435 (EGF)
04630 JAK-STAT signaling pathway
461435 (EGF)
04066 HIF-1 signaling pathway
461435 (EGF)
04068 FoxO signaling pathway
461435 (EGF)
04020 Calcium signaling pathway
461435 (EGF)
04072 Phospholipase D signaling pathway
461435 (EGF)
04151 PI3K-Akt signaling pathway
461435 (EGF)
09133 Signaling molecules and interaction
04518 Integrin signaling
461435 (EGF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
461435 (EGF)
04540 Gap junction
461435 (EGF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
461435 (EGF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
461435 (EGF)
05207 Chemical carcinogenesis - receptor activation
461435 (EGF)
05208 Chemical carcinogenesis - reactive oxygen species
461435 (EGF)
05231 Choline metabolism in cancer
461435 (EGF)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
461435 (EGF)
09162 Cancer: specific types
05210 Colorectal cancer
461435 (EGF)
05212 Pancreatic cancer
461435 (EGF)
05226 Gastric cancer
461435 (EGF)
05214 Glioma
461435 (EGF)
05218 Melanoma
461435 (EGF)
05219 Bladder cancer
461435 (EGF)
05215 Prostate cancer
461435 (EGF)
05213 Endometrial cancer
461435 (EGF)
05224 Breast cancer
461435 (EGF)
05223 Non-small cell lung cancer
461435 (EGF)
09172 Infectious disease: viral
05160 Hepatitis C
461435 (EGF)
05165 Human papillomavirus infection
461435 (EGF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
461435 (EGF)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
ptr04052
]
461435 (EGF)
Cytokines and neuropeptides [BR:
ptr04052
]
Cytokines
Growth factors (RTK binding)
461435 (EGF)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
cEGF
EGF
EGF_CA
EGF_3
LRP1-like_beta_prop
EGF_TGFA-like
EGF_Epiregulin
Vgb_lyase
Plasmod_Pvs28
Motif
Other DBs
NCBI-GeneID:
461435
NCBI-ProteinID:
XP_009446410
Ensembl:
ENSPTRG00000016367
VGNC:
10856
LinkDB
All DBs
Position
3:111369488..111470783
Genome browser
AA seq
1215 aa
AA seq
DB search
MLLTLIVLLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
MAINWINEEVIWSNQQEGIITVTDMKGNNSHVLLSALKYPANIAVDPVERFIFWSSEVAG
SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
SKHPTQHNLFAMSLFGDRIFYSIWKMKTIWIANKHTGKDMVRINLHSPFVPPGELKVVHP
LAQPKAEDDTWEPEQKLRKLRKGNCSSTVCGQDLQSHLCTCAEGYALSRDRKYCEDVNEC
AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPSNVSECSHDCVLTSEGPL
CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCIPLSPVSWECDCFPGYDLQLDKKSCAASG
PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQP
RGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCD
AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNKRTGKDRVR
LQGSMLKPSSLVVVHPLAKPGAEPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
LALDGHQLLAGGEVDLKNQVTPLDILSQTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
STYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
EGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
ELRHAGHGQQQKVIVVAVCVVVLVVLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGQFLSLAPGSMQPTSWR
QEPRLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLW
QQRALDPPHQMELTQ
NT seq
3648 nt
NT seq
+upstream
nt +downstream
nt
atgctgctcactcttatcgttctgttgccagtagtttcaaaatttagttttgttagtctc
tcagcaccgcagcactggagctgtcctgaaggtactcttgcaggaaatgggaattctact
tgtgtgggtcctgcacccttcttaattttctcccacggaaatagtatctttaggattgac
acagaaggaaccaattatgagcaattggtggtggatgctggtgtctcagtgatcatggat
tttcattataatgagaaaagaatctattgggtggatttagaaagacaacttttgcaaaga
gtttttctgaatgggtcaaggcaagagagagtatgtaatatagagaaaaatgtttctgga
atggcaataaattggataaatgaagaagttatttggtcaaatcaacaggaaggaatcatt
acagtaacagatatgaaaggaaataattcccacgttcttttaagtgctttaaaatatcct
gcaaatatagcagttgatccagtagaaaggtttatattttggtcttcagaggtggctgga
agcctttatagagcagatctcgatggtgtgggagtgaaggctctgttggagacatcagag
aaaataacagctgtgtcattggatgtgcttgataagcggctgttttggattcagtacaac
agagaaggaagcaattctcttatttgctcctgtgattatgatggaggttctgtccacatt
agtaaacatccaacacagcacaatttgtttgcaatgtccctttttggtgaccgtatcttc
tattcaatatggaaaatgaagacaatttggatagccaacaaacacactggaaaggacatg
gttagaattaacctccattcaccatttgtaccacctggtgaactgaaagtagtgcatcca
cttgcacaacccaaggcagaagatgacacttgggagcctgagcagaaacttcgcaaattg
aggaaaggaaactgcagcagcactgtgtgtgggcaagacctccagtcacacttgtgcacg
tgtgcagagggatacgccctaagtcgagaccggaagtactgtgaagatgttaatgaatgc
gctttttggaatcatggctgtactcttgggtgtaaaaacacccctggatcctattactgc
acatgccctgtaggatttgttctgcttcctgatgggaaacgatgtcatcaacttgtttcc
tgtccaagcaatgtgtctgaatgcagccatgactgtgttctgacatcagaaggtccctta
tgtttctgtcctgaaggctcggtgcttgagagagatgggaaaacatgtagcggttgttcc
tcacctgataatggtggatgtagccagctctgcattcctcttagcccagtatcctgggaa
tgtgattgctttcctgggtatgacctacaactggataaaaaaagctgtgcagcttcagga
ccacaaccatttttgctgtttgccaattctcaagatattcgacacatgcattttgatgga
acagactatggaactctgctcagccagcagatgggaatggtttatgccctagatcatgac
cctgtggaaaataagatatactttgcccatacagccctgaagtggatagagagagctaat
atggatggttcccagcgagaaaggcttattgaggaaggagtagatgtgccagaaggtctt
gctgtggactggattggccgtagattctattggacagacagagggaaatctctgattgga
aggagtgatttaaatgggaaacgttccaaaataatcactaaggagaacatctctcaacca
cgaggaattgctgttcatccaatggccaagagattattctggactgatacagggattaat
ccacgaattgaaagttcttccctccaaggccttggccgactggttatagccagctctgat
ctaatctggcccagtggaataacgattgacttcttaactgacaagttgtattggtgcgat
gccaagcagtctgtgattgaaatggccaatctggatggttcaaaacgccgaagacttacc
cagaatgatgtaggtcacccatttgctgtagcagtgtttgaggattatgtgtggttctca
gattgggctatgccatcagtaataagagtaaacaagaggactggcaaagatagagtacgt
ctccaaggcagcatgctgaagccctcatcactggttgtggttcatccattggcaaaacca
ggagcagagccctgcttatatcaaaacggaggctgtgaacatatttgcaaaaagaggctt
ggaactgcttggtgttcgtgtcgcgaaggttttatgaaagcctcagatgggaaaacgtgt
ctggctctggatggtcatcagctgttggcaggtggtgaagttgatctaaagaaccaagta
acaccattggacatcttgtcccagactagagtgtcagaagataacattacagaatctcaa
cacatgctagtggctgaaatcatggtgtcagatcaagatgactgtgctcctgtgggatgc
agcacgtatgctcggtgtatttcagagggagaggatgccacatgtcagtgtttgaaagga
tttgctggggatggaaaactatgttctgatatagatgaatgtgagatgggtgtcccagtg
tgcccccctgcctcctccaagtgcatcaacaccgaaggtggttatgtctgccggtgctca
gaaggctaccaaggagatgggattcactgtctcgatattgatgagtgccaactgggggtg
cacagctgtggagagaatgccagctgcacaaatacagagggaggctatacctgcatgtgt
gctggacgcctgtctgaaccaggactgatttgccctgactctactccaccccctcacctc
agggaagatgaccaccactattccgtaagaaatagtgactctgaatgtcccctgtcccac
gatgggtactgcctccatgatggtgtgtgcatgtatattgaagcattggacaagtatgca
tgcaactgtgttgttggctacatcggggagcgatgtcagtaccgagacctgaagtggtgg
gaactgcgccacgctggccacgggcagcagcagaaggtcatcgtggtggctgtctgcgtg
gtggtgcttgtcgtgctgctcctcctgagcctgtggggggcccactactacaggactcag
aagctgctatcgaaaaacccaaagaatccttatgaggagtcgagcagagacgtgaggagt
cgcaggcctgctgacactgaggatgggatgtcctcttgccctcaaccttggtttgtggtt
ataaaagaacaccaagacctcaagaatgggggtcaaccagtggctggtgaggatggccag
gcagcagatggtcagtttttatccctggctcctgggtcaatgcaaccaacttcatggagg
caggagccccggttatgtggaatgggcacagagcaaggctgctggattccagtatccagt
gataagggctcctgtccccaggtaatggagcgaagctttcatatgccctcttatgggaca
cagacccttgaagggggtgtcgagaagccccattctctcctatcagctaacccattatgg
caacaaagggccctggacccaccacaccaaatggagctgactcagtga
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