Pan troglodytes (chimpanzee): 461892
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Entry
461892 CDS
T01005
Symbol
HMGCS1
Name
(RefSeq) hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00280
Valine, leucine and isoleucine degradation
ptr00650
Butanoate metabolism
ptr00900
Terpenoid backbone biosynthesis
ptr01100
Metabolic pathways
ptr03320
PPAR signaling pathway
Module
ptr_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
461892 (HMGCS1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
461892 (HMGCS1)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
461892 (HMGCS1)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
461892 (HMGCS1)
Enzymes [BR:
ptr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
461892 (HMGCS1)
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GFIT
Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
Cullin
PS_Dcarbxylase
Motif
Other DBs
NCBI-GeneID:
461892
NCBI-ProteinID:
XP_003310783
Ensembl:
ENSPTRG00000016845
VGNC:
4035
UniProt:
A0A2I3TUA8
A0A6D2XV98
H2QQU5
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Position
4:69483550..69508512
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AA seq
601 aa
AA seq
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MASSFLLIGRSRTGGRALPGNSTGRDWLLEPPSRLPATLGGAGVGWVGGYKAGGEGEAPR
TVLSWLTPFPLLPLGHACSFTMPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKY
DGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIID
KSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGD
IAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGK
LSIQCYLSALDRCYSVYCKKIRAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARML
LNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFSQKTKASLLVSN
QNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALD
KITASLCDLKSRLDSRTGVAPDVFAENMKLREDTHHLVNYIPQGSIDSLFEGTWYLVRVD
EKHRRTYARRPTPNDDTLDEGVGLVHSNIATEHIPSPAKKVPRLPATAAEPEAAVISNGE
H
NT seq
1806 nt
NT seq
+upstream
nt +downstream
nt
atggcctctagtttccttttgattggtagaagccggactggggggcgggcgctgccgggc
aactctaccggccgcgattggctgctggagccaccgtcccgcctcccagcgactctcggc
ggtgccggagtcgggtgggttggcggctataaagctggtggcgaaggggaggcgccgcgg
actgtcctttcgtggctcactccctttcctctgctgccgctcggtcacgcttgctctttc
accatgcctggatcacttcctttgaatgcagaagcttgctggccaaaagatgtgggaatc
gttgcccttgagatctattttccttctcaatatgttgatcaagcagagttggaaaaatat
gatggtgtagatgctggaaagtataccattggcttgggccaggccaagatgggcttctgc
acagatagagaagatattaactctctttgcatgactgtggttcagaatcttatggagaga
aataacctttcctatgattgcattgggcggctggaagttggaacagagacaatcatcgac
aaatcaaagtctgtgaagactaatttgatgcagctgtttgaagagtctgggaatacagat
atagaaggaatcgacacaactaatgcatgctatggaggcacagctgctgtcttcaatgct
gttaactggattgaatccagctcttgggatggacggtatgccctggtagttgcaggagat
attgctgtatatgccacaggaaatgctagacctacaggtggagttggagcagtagctctg
ctaattgggccaaatgctcctttaatttttgaacgagggcttcgtgggacacatatgcaa
catgcctatgatttttacaagcctgatatgctatctgaatatcctatagtagatggaaaa
ctctccatacagtgctacctcagtgcattagaccgctgctattctgtctactgcaaaaag
atccgtgcccagtggcagaaagagggaaatgataaagattttaccttgaatgattttggc
ttcatgatctttcactcaccatattgtaaactggttcagaaatctctagctcggatgttg
ctgaatgacttccttaatgaccagaatagagataaaaatagtatctatagtggcctggaa
gcctttggggatgttaaattagaagacacctactttgatagagatgtggagaaggcattt
atgaaggctagctctgaactcttcagtcagaaaacaaaggcatctttacttgtatcaaat
caaaatggaaatatgtacacatcttcagtatatggttcccttgcatctgttctagcacag
tactcacctcagcaattagcagggaagagaattggagtgttttcttatggttctggtttg
gctgccactctgtactctcttaaagtcacacaagatgctacaccagggtctgctcttgat
aaaataacagcaagtttatgtgatcttaaatcaaggcttgattcaagaactggtgtggca
ccagatgtcttcgctgaaaacatgaagctcagagaggacacccatcatttggtcaactat
attccccagggttcaatagattcactctttgaaggaacgtggtacttagttagggtggat
gaaaagcacagaagaacttacgctcggcgtcccactccaaatgatgacactttggatgaa
ggagtaggacttgtgcattcaaacatagcaactgagcatattccaagccctgccaagaaa
gtaccaagactccctgccacagcagcagaacctgaagcagctgtcattagtaatggggaa
cattaa
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