Pan troglodytes (chimpanzee): 462019
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Entry
462019 CDS
T01005
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2 isoform X1
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00120
Primary bile acid biosynthesis
ptr01040
Biosynthesis of unsaturated fatty acids
ptr01100
Metabolic pathways
ptr01212
Fatty acid metabolism
ptr04146
Peroxisome
Module
ptr_M00104
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
ptr_M00861
beta-Oxidation, peroxisome, VLCFA
ptr_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
462019 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
462019 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
462019 (HSD17B4)
Enzymes [BR:
ptr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
462019 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
462019 (HSD17B4)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MFE-2_hydrat-2_N
MaoC_dehydratas
adh_short
adh_short_C2
SCP2
KR
Alkyl_sulf_C
FAS1_DH_region
AbrB-like
Motif
Other DBs
NCBI-GeneID:
462019
NCBI-ProteinID:
XP_003310890
Ensembl:
ENSPTRG00000017168
VGNC:
13510
UniProt:
A0A8I3B362
K7B5J8
LinkDB
All DBs
Position
4:117201129..117286566
Genome browser
AA seq
736 aa
AA seq
DB search
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHDSCEENGGLFEVG
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
AYVDLAPTSDTSAKTPSEGEKLQSTLVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
MLSQKLQMILKDYAKL
NT seq
2211 nt
NT seq
+upstream
nt +downstream
nt
atgggctcaccgctgaggttcgacgggcgggtggtactggtcaccggcgcgggggcagga
ttgggccgagcctatgccctggcttttgcagaaagaggagcgttagttgttgtgaatgat
ttgggaggggacttcaaaggagttggtaaaggctccttagctgctgataaggttgttgaa
gaaataagaaggagaggtggaaaagcagtggccaactatgattcagtggaagaaggagag
aaggttgtgaagacagccctggatgcttttggaagaatagatgttgtggtcaacaatgct
ggaattctgagggatcgttcctttgctaggataagtgatgaagactgggatataatccac
agagttcatttgcggggttcattccaagtgacacgggcagcatgggaacacatgaagaaa
cagaagtatggaaggattattatgacttcatcagcttcaggaatatatggcaactttggc
caggccaattatagtgctgcaaagttgggtcttctgggccttgcaaattctcttgcaatt
gaaggcaggaaaagcaacattcattgtaacaccattgctcctaatgcgggatcacggatg
actcagacagttatgcctgaagatcttgtggaagccctgaagccagagtatgtggcaccc
cttgtcctttggctttgtcacgacagttgtgaggagaatggtggcttgtttgaggttgga
gcaggatggattggaaaattacgctgggagcggactcttggagctattgtaagacaaaag
aatcacccaatgactcctgaggcagtcaaggctaactggaagaagatctgtgactttgag
aatgccagcaagcctcagagtatccaagaatcaactggcagtataattgaagttctgagt
aaaatagattcagaaggaggagtttcagcaaatcatactagtcgtgcaacgtctacagca
acatcaggatttgctggagctattggccagaaactccctccattttcttatgcttatacg
gaactggaagctattatgtatgcccttggagtgggagcatcaatcaaggatccaaaagat
ttgaaatttatttatgaaggaagttctgatttctcctgtttgcccaccttcggagttatc
ataggtcagaaatctatgatgggtggaggattagcagaaattcctggactttcaatcaac
tttgcaaaggttcttcatggagagcagtacttagagttatataaaccacttcccagagca
ggaaaattaaaatgtgaagcagttgttgctgatgtcctagataaaggatccggtgtagtg
attattatggatgtctattcttattctgagaaggaacttatatgccacaatcagttctct
ctctttcttgttggctctggaggctttggtggaaaacggacatcagacaaagtcaaggta
gctgtagccatacctaatagacctcctgatgctgtacttacagataccacctctcttaat
caggctgctttgtaccgcctcagtggagactggaatcccttacacattgatcctaacttt
gctagtctagcaggttttgacaagcccatattacatggattatgtacatttggattttct
gccaggcgtgttttacagcagtttgcagataatgatgtgtcaagattcaaggcaattaag
gctcgttttgcaaaaccagtatatccaggacaaactctacaaactgagatgtggaaggaa
ggaaacagaattcattttcaaaccaaggtccaagaaactggagacattgtcatttcaaat
gcatatgtggatcttgcaccaacatctgatacttcagctaagacaccctctgagggcgag
aagcttcagagtacccttgtatttgaggaaataggacgccgcctaaaggatattgggcct
gaggtggtgaagaaagtaaatgctgtatttgagtggcatataaccaaaggcggaaatatt
ggggctaagtggactattgacctgaaaagtggttctggaaaagtgtaccaaggccctgca
aaaggtgctgctgatacaacaatcatactttcagatgaagatttcatggaggtggtcctg
ggcaagcttgaccctcagaaggcattctttagtggcaggctgaaggccagagggaacatc
atgctgagccagaaacttcagatgattcttaaagactatgccaagctctga
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