Pan troglodytes (chimpanzee): 462333 Help Entry 462333            CDS       T01005                                  Symbol SQSTM1 Name (RefSeq) sequestosome-1 isoform X1   KO K14381   sequestosome 1 Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr04137   Mitophagy - animal ptr04140   Autophagy - animal ptr04217   Necroptosis ptr04218   Cellular senescence ptr04380   Osteoclast differentiation ptr05014   Amyotrophic lateral sclerosis ptr05022   Pathways of neurodegeneration - multiple diseases ptr05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:ptr00001]  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     462333 (SQSTM1)    04137 Mitophagy - animal     462333 (SQSTM1)   09143 Cell growth and death    04217 Necroptosis     462333 (SQSTM1)    04218 Cellular senescence     462333 (SQSTM1)  09150 Organismal Systems   09158 Development and regeneration    04380 Osteoclast differentiation     462333 (SQSTM1)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     462333 (SQSTM1)    05022 Pathways of neurodegeneration - multiple diseases     462333 (SQSTM1)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     462333 (SQSTM1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ptr04131]     462333 (SQSTM1)    03029 Mitochondrial biogenesis [BR:ptr03029]     462333 (SQSTM1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ptr04147]     462333 (SQSTM1) Membrane trafficking [BR:ptr04131]  Autophagy   Mitophagy    Cargo receptors     462333 (SQSTM1)   Pexophagy     462333 (SQSTM1)   Aggrephagy     462333 (SQSTM1)   Xenophagy     462333 (SQSTM1)   Other autophagy associated proteins    Midbophagy     462333 (SQSTM1) Mitochondrial biogenesis [BR:ptr03029]  Mitochondrial quality control factors   Mitophagy factors    Parkin-dependent mechanism factors     462333 (SQSTM1) Exosome [BR:ptr04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    462333 (SQSTM1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  UBA_5 PB1 ZZ Motif Other DBs NCBI-GeneID:  462333 NCBI-ProteinID:  XP_001153075 Ensembl:  ENSPTRG00000017626 VGNC:  4180 UniProt:  H2R540 A0A6D2XMZ4 LinkDB All DBs Position 5:157751443..157781538 Genome browser AA seq 440 aa AA seqDB search MASLTVKAYLLGKEDAAREIRRFSFCFSPEPEAEAEAAAGPGPCERLLSRVAALFPALRP GGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRN MVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFS HSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNV GESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNV EGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPE SEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTK NYDIGAALDTIQYSKHPPPL NT seq 1323 nt NT seq  +upstreamnt  +downstreamnt atggcgtcgctcaccgtgaaggcctaccttctgggcaaggaggacgcggcgcgcgagatt cgccgcttcagcttctgcttcagccccgagcctgaggcggaagccgaggctgcggcaggt ccgggaccctgcgagcggctgctgagccgggtggccgccctgttccccgcgctgcggcct ggcggcttccaggcgcactaccgcgatgaggacggggacttggttgccttttccagtgac gaggaattgacaatggccatgtcctacgtgaaggatgacatcttccgaatctacattaaa gagaaaaaagagtgccggcgggaccaccgcccaccgtgtgctcaggaggcgccccgcaac atggtgcaccccaatgtgatctgtgatggctgcaatgggcctgtggtgggaacccgctac aagtgcagcgtctgcccagactacgacttgtgtagcgtctgcgagggaaagggcttgcac cgggggcacaccaagctcgcgttccccagccccttcgggcacctgtctgagggcttctcg cacagccgctggctccggaaggtgaaacacggacacttcgggtggccaggatgggaaatg ggtccaccaggaaactggagcccacgtcctcctcgtgcaggggaggcccgccctggcccc acggcggaatcagcttctggtccatcggaggatcccagtgtgaatttcctgaagaacgtt ggggagagtgtggcagctgcccttagccctctgggcattgaagttgatatcgatgtggag cacggagggaaaagaagccgcctgacccccgtctctccagagagttccagcacagaggag aagagcagctcacagccaagcagctgctgctctgaccccagcaagccgggtgggaatgtt gagggcgccacgcagtctctggcagagcagatgagaaagatcgccttggagtccgagggg cgccctgaggaacagatggagtcggataactgttcaggaggagatgatgactggacccat ctgtcttcaaaagaagtggacccgtctacaggtgaactccagtccctacagatgccagaa tccgaagggccaagctctctggacccctcccaggagggacccacagggctgaaggaagct gccttgtacccgcatctcccgccagaggctgacccgcggctgattgagtccctctcccag atgctgtccatgggcttctctgatgaaggcggctggctcaccaggctcctgcagaccaag aactatgacatcggggcggctctggacaccatccagtattcaaagcatcccccgccgttg tga

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