Pan troglodytes (chimpanzee): 463023
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Entry
463023 CDS
T01005
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01524
Platinum drug resistance
ptr04010
MAPK signaling pathway
ptr04071
Sphingolipid signaling pathway
ptr04141
Protein processing in endoplasmic reticulum
ptr04210
Apoptosis
ptr04530
Tight junction
ptr04668
TNF signaling pathway
ptr04714
Thermogenesis
ptr04722
Neurotrophin signaling pathway
ptr04932
Non-alcoholic fatty liver disease
ptr04936
Alcoholic liver disease
ptr05010
Alzheimer disease
ptr05012
Parkinson disease
ptr05014
Amyotrophic lateral sclerosis
ptr05016
Huntington disease
ptr05017
Spinocerebellar ataxia
ptr05022
Pathways of neurodegeneration - multiple diseases
ptr05208
Chemical carcinogenesis - reactive oxygen species
ptr05417
Lipid and atherosclerosis
ptr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
463023 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
463023 (MAP3K5)
04668 TNF signaling pathway
463023 (MAP3K5)
04071 Sphingolipid signaling pathway
463023 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
463023 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
463023 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
463023 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
463023 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
463023 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
463023 (MAP3K5)
05012 Parkinson disease
463023 (MAP3K5)
05014 Amyotrophic lateral sclerosis
463023 (MAP3K5)
05016 Huntington disease
463023 (MAP3K5)
05017 Spinocerebellar ataxia
463023 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
463023 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
463023 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
463023 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
463023 (MAP3K5)
04932 Non-alcoholic fatty liver disease
463023 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
463023 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
463023 (MAP3K5)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
463023 (MAP3K5)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: STE group
STE11 family
463023 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
463023
NCBI-ProteinID:
XP_016811860
Ensembl:
ENSPTRG00000024326
VGNC:
10797
LinkDB
All DBs
Position
5:complement(148405159..148671413)
Genome browser
AA seq
1506 aa
AA seq
DB search
MKASCRLGGRRVLSAAAAAVPGRRLGSQPARKRASGAATEAPRRSEPPPGSGVPSGERAP
ERRRRRGGEGAARDGSCLARRARSSPELWLARRCGWAGDAAAVAARPGEMSTEADEGITF
SVPPFAPSGFCTIPEGGICRRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAAT
SSSSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLH
FGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDS
LQSLKEIICQKNTTWDSICAVSPGQLPTCRCLLSLQMCTGNYTFVPYMITPHNKVYCCDS
SFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYT
GKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASH
HHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTD
TESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGN
LEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLT
TEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISI
WHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFE
MVNTITEEKGRSTEEGDCESDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAI
KEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRS
KWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKR
LAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQ
AAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQ
PKLSALSAGSNEYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGER
DVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKIVRN
LMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQ
VVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTAD
QEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRM
KIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSSGTNT
EDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIID
FRNKQT
NT seq
4521 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcgagctgccgcctaggagggaggagggtcctttcggctgccgctgctgctgtt
ccgggacgccgcctggggagccagcccgctcgtaagagggcgagcggcgcggccacggag
gcgccgaggaggagcgagccgccgccgggcagcggcgtgccctcgggggagagggcgccg
gagaggaggcggcggcgcggcggcgagggcgcggcgcgcgatggcagctgcttagcccgg
cgggcgcggagcagccccgagctgtggctggccaggcggtgcggctgggcgggggacgcc
gccgccgttgctgcccggcccggagagatgagcacggaggcggacgagggcatcactttc
tctgtgccacccttcgccccctcgggcttctgcaccatccccgagggcggcatctgcagg
aggggaggagcggcggcggtgggcgagggcgaggagcaccagctgccaccgccgccgccg
ggcagcttctggaacgtggagagcgccgctgcccctggcatcggttgtccggcggccacc
tcctcgagcagtgccacccgaggccggggcagctctgttggcgggggcagccgacggacc
acggtggcatatgtgatcaacgaagcgagccaggggcaactggtggtggccgagagcgag
gccctgcagagcttgcgggaggcgtgcgagacagtgggcgccaccctggaaaccctgcat
tttgggaaactcgactttggagaaaccaccgtgctggaccgcttttacaatgcagatatt
gcggtggtggagatgagcgatgccttccggcagccgtccttgttttaccaccttggggtg
agagaaagtttcagcatggccaacaacatcatcctctactgtgatactaactcggactct
ctgcagtcactgaaggaaatcatttgccagaagaatactacgtgggattccatctgtgcc
gtgtctccaggccagctccccacttgccgatgcctcctctctctgcagatgtgcactggg
aactacacctttgttccttacatgataactccacataacaaagtctactgctgtgacagc
agcttcatgaaggggttgacagagctcatgcaaccgaacttcgagctgcttcttggaccc
atctgcttacctcttgtggatcgttttattcaacttttgaaggtggcacaagcaagttct
agccagtacttccgggaatctatactcaatgacatcaggaaagctcgtaatttatacact
ggtaaagaattggcagctgagttggcaagaattcggcagcgagtagataatatcgaagtc
ttgacagcagatattgtcataaatctgttactttcctacagagatatccaggactatgat
tctattgtgaagctggtagagactttagaaaaactgccaacctttgatttggcctcccat
caccatgtgaagtttcattatgcatttgcactgaataggagaaatctccctggtgacaga
gcaaaagctcttgatattatgattcccatggtgcaaagtgaaggacaagttgcttcagat
atgtattgcctagttggtcgaatctacaaagatatgtttttggactctaatttcacggac
actgaaagcagagaccatggagcttcttggttcaaaaaggcatttgaatctgagccaaca
ctacagtcaggaattaattatgcggtcctcctcctggcagctggacaccagtttgaatct
tcctttgagctccggaaagttggggtgaagctaagtagtcttcttggtaaaaagggaaac
ttggaaaaactccagagctactgggaagttggattttttctgggggccagcgtcctagcc
aatgaccacatgagagtcattcaagcatctgaaaagctttttaaactgaagacaccagca
tggtacctcaagtctattgtagagacaattttgatatataagcattttgtgaaactgacc
acagaacagcctgtggccaagcaagaacttgtggacttttggatggatttcctggtcgag
gccacaaagacagatgttactgtggttaggtttccagtattaatattagaaccaaccaaa
atctatcaaccttcttatttgtctatcaacaatgaagttgaggaaaagacaatctctatt
tggcacgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcctcttct
gtcaggggagtgagtatttctaaatttgaagaaagatgctgctttctttatgtgcttcac
aattctgatgatttccaaatctatttctgtacagaacttcattgtaaaaagttttttgag
atggtgaacaccattaccgaagagaaggggagaagcacagaggaaggagactgtgaaagt
gactcgctggagtatgactatgaatatgatgaaaatggtgacagagtcgttttaggaaaa
ggcacttacgggatagtctacgcaggtcgggacttgagcaaccaagtcagaattgctatt
aaggaaatcccagagagagacagcagatactctcagcccctgcatgaagaaatagcattg
cataaacacctgaagcacaaaaatattgtccagtatctgggctctttcagtgagaatggt
ttcattaaaatcttcatggagcaggtccctggaggaagtctttctgctctccttcgttcc
aaatggggtccattaaaagacaatgagcaaacaattggcttttatacaaagcaaatactg
gaaggattaaaatatctccatgacaatcagatagttcaccgggacataaagggtgacaat
gtgttgattaatacctacagtggtgttctcaagatctctgacttcgggacatcaaagagg
cttgctggcataaacccctgtactgaaacttttactggtaccctccagtatatggcacca
gaaataatagataaaggaccaagaggctacggaaaagcagcagacatctggtctctgggc
tgtacaatcattgaaatggccacaggaaaacccccattttatgaactgggagaaccacaa
gcagctatgttcaaggtgggaatgtttaaagtccaccctgagatcccagagtccatgtct
gcagaggccaaggcattcatactgaaatgttttgaaccagatcctgacaagagagcctgt
gctaacgacttgcttgttgatgagtttttaaaagtttcaagcaaaaagaaaaagacacaa
cctaagctttcagctctttcagctggatcaaatgaatatctcaggagtatatccttgccg
gtacctgtgctggtggaggacaccagcagcagcagtgagtacggctcagtttcacccgac
acggagttgaaagtggaccccttctctttcaaaacaagagccaagtcctgcggagaaaga
gatgtcaagggaattcggacactctttttgggcattccagatgagaattttgaagatcac
agtgctcctccttcccctgaagaaaaagattctggattcttcatgctgaggaaggacagt
gagaggcgagctacccttcacaggatcctgacggaagaccaagacaaaattgtgagaaac
ctaatggaatctttagctcagggggctgaagaaccaaaactaaaatgggaacacatcaca
accctcattgcaagcctcagagaatttgtgagatccactgaccgaaaaatcatagccacc
acattgtcaaagctgaaactggagctggacttcgacagccatggcattagccaagtccag
gtggtactctttggttttcaagatgctgtcaataaagttcttcggaatcataacatcaag
ccgcactggatgtttgccttagacagtatcattcggaaggcggtacagacagccattacc
atcctggttccagaactaaggccacatttcagccttgcatctgagagtgatactgctgat
caagaagacttggatgtagaagatgaccatgaggaacagccttcaaatcaaactgtccga
agacctcaggctgtcattgaagatgctgtggctacctcaggtgtgagcacgctcagttct
actgtgtctcatgattcccagagtgctcaccggtcactgaatgtacagcttggaaggatg
aaaatagaaaccaatagattactggaagaattggttcggaaagagaaagaattacaagca
ctccttcatcgagctattgaagaaaaagaccaagaaattaaacacctgaagcttaagtcc
caacccatagaaattcctgaattgcctgtatttcatctaaattcttctggcacaaatact
gaagattctgaacttaccgactggctgagagtgaatggagctgatgaagacactataagc
cggtttttggctgaagattatacactattggatgttctctactatgttacacgtgatgac
ttaaaatgcttgagactaaggggagggatgctgtgcacactgtggaaggctatcattgac
tttcgaaacaaacagacttga
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