Pan troglodytes (chimpanzee): 464400
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Entry
464400 CDS
T01005
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8 isoform X1
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00230
Purine metabolism
ptr01100
Metabolic pathways
ptr01522
Endocrine resistance
ptr04015
Rap1 signaling pathway
ptr04020
Calcium signaling pathway
ptr04022
cGMP-PKG signaling pathway
ptr04024
cAMP signaling pathway
ptr04062
Chemokine signaling pathway
ptr04072
Phospholipase D signaling pathway
ptr04081
Hormone signaling
ptr04082
Neuroactive ligand signaling
ptr04114
Oocyte meiosis
ptr04211
Longevity regulating pathway
ptr04213
Longevity regulating pathway - multiple species
ptr04261
Adrenergic signaling in cardiomyocytes
ptr04270
Vascular smooth muscle contraction
ptr04371
Apelin signaling pathway
ptr04540
Gap junction
ptr04611
Platelet activation
ptr04713
Circadian entrainment
ptr04714
Thermogenesis
ptr04720
Long-term potentiation
ptr04723
Retrograde endocannabinoid signaling
ptr04724
Glutamatergic synapse
ptr04725
Cholinergic synapse
ptr04727
GABAergic synapse
ptr04742
Taste transduction
ptr04750
Inflammatory mediator regulation of TRP channels
ptr04911
Insulin secretion
ptr04912
GnRH signaling pathway
ptr04913
Ovarian steroidogenesis
ptr04914
Progesterone-mediated oocyte maturation
ptr04915
Estrogen signaling pathway
ptr04916
Melanogenesis
ptr04918
Thyroid hormone synthesis
ptr04921
Oxytocin signaling pathway
ptr04923
Regulation of lipolysis in adipocytes
ptr04925
Aldosterone synthesis and secretion
ptr04926
Relaxin signaling pathway
ptr04927
Cortisol synthesis and secretion
ptr04928
Parathyroid hormone synthesis, secretion and action
ptr04934
Cushing syndrome
ptr04935
Growth hormone synthesis, secretion and action
ptr04970
Salivary secretion
ptr04971
Gastric acid secretion
ptr04972
Pancreatic secretion
ptr04976
Bile secretion
ptr05032
Morphine addiction
ptr05163
Human cytomegalovirus infection
ptr05166
Human T-cell leukemia virus 1 infection
ptr05200
Pathways in cancer
ptr05207
Chemical carcinogenesis - receptor activation
ptr05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
464400 (ADCY8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
464400 (ADCY8)
04072 Phospholipase D signaling pathway
464400 (ADCY8)
04024 cAMP signaling pathway
464400 (ADCY8)
04022 cGMP-PKG signaling pathway
464400 (ADCY8)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
464400 (ADCY8)
04081 Hormone signaling
464400 (ADCY8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
464400 (ADCY8)
04062 Chemokine signaling pathway
464400 (ADCY8)
09152 Endocrine system
04911 Insulin secretion
464400 (ADCY8)
04923 Regulation of lipolysis in adipocytes
464400 (ADCY8)
04913 Ovarian steroidogenesis
464400 (ADCY8)
04915 Estrogen signaling pathway
464400 (ADCY8)
04921 Oxytocin signaling pathway
464400 (ADCY8)
04926 Relaxin signaling pathway
464400 (ADCY8)
04935 Growth hormone synthesis, secretion and action
464400 (ADCY8)
04918 Thyroid hormone synthesis
464400 (ADCY8)
04928 Parathyroid hormone synthesis, secretion and action
464400 (ADCY8)
04925 Aldosterone synthesis and secretion
464400 (ADCY8)
04927 Cortisol synthesis and secretion
464400 (ADCY8)
09154 Digestive system
04970 Salivary secretion
464400 (ADCY8)
04971 Gastric acid secretion
464400 (ADCY8)
04972 Pancreatic secretion
464400 (ADCY8)
04976 Bile secretion
464400 (ADCY8)
09156 Nervous system
04724 Glutamatergic synapse
464400 (ADCY8)
04727 GABAergic synapse
464400 (ADCY8)
04725 Cholinergic synapse
464400 (ADCY8)
04720 Long-term potentiation
464400 (ADCY8)
04723 Retrograde endocannabinoid signaling
464400 (ADCY8)
09157 Sensory system
04742 Taste transduction
464400 (ADCY8)
04750 Inflammatory mediator regulation of TRP channels
464400 (ADCY8)
09149 Aging
04211 Longevity regulating pathway
464400 (ADCY8)
04213 Longevity regulating pathway - multiple species
464400 (ADCY8)
09159 Environmental adaptation
04713 Circadian entrainment
464400 (ADCY8)
04714 Thermogenesis
464400 (ADCY8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
464400 (ADCY8)
05207 Chemical carcinogenesis - receptor activation
464400 (ADCY8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
464400 (ADCY8)
05163 Human cytomegalovirus infection
464400 (ADCY8)
09165 Substance dependence
05032 Morphine addiction
464400 (ADCY8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
464400 (ADCY8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
464400 (ADCY8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
464400 (ADCY8)
Enzymes [BR:
ptr01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
464400 (ADCY8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
AC_N
Adcy_cons_dom
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
464400
NCBI-ProteinID:
XP_016815358
Ensembl:
ENSPTRG00000020589
VGNC:
12015
UniProt:
A0A6D2X3V0
A0A2I3SK46
LinkDB
All DBs
Position
7:complement(141033581..141296401)
Genome browser
AA seq
1251 aa
AA seq
DB search
MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGS
GSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASG
SGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRK
SEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHT
YLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTS
LLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEAR
LRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADV
KGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAH
CCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKL
ESGGIPGRIHISKATLDCLDGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPED
IVKESVSSSDQRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHV
QSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAF
IVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINE
TYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTG
VLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEA
SLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVA
RHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDE
LLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKH
SFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLIL
KDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLV
QSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
atggagctctccgatgtgcgctgccttacaggcagcgaggaactctacaccatccacccg
acgcccccggccggcgacggcaggagcgcctcccggccgcagcggctgctgtggcagacg
gcggtgcgacacatcacggagcagcgcttcattcacgggcaccggggaggcagcggcagc
gggagtggaggctcgggcaaagcctcggaccctgcgggcggcggccccaaccaccacgcg
ccgcagctgtcaggcgactcggcgctgcccctctactcgctgggcccaggagagcgagcg
cacagcacctgcggcaccaaagtcttcccggaacgcagcgggagcggcagtgccagcggc
agcggaggcgggggcgacctgggcttcctgcaccttgactgtgcccctagcaactcggat
ttctttcttaatgggggctatagctaccgaggggtcattttccccaccctgcgcaactcc
ttcaaatctcgggatttggaacgcctctaccagcgctatttcttgggccaaaggcgcaaa
tcggaagtggtgatgaacgtgctggacgtgctgaccaaactcactctcttggtcctacac
ttgagcctggcctcggcccccatggacccgctcaagggcatcctgctgggcttcttcacc
ggcattgaggtagtgatctgcgccctggtggtggtcaggaaggacaccacctcccacacg
tacctgcagtacagcggcgtggtcacctgggtggccatgaccacccagatcctggcagca
ggcctcggctacgggctcctgggcgacggcataggctacgtgctcttcacgctcttcgcc
acctacagtatgctgccgctgccgctcacctgggccatcctggccggcctgggcacctcg
ctgctgcaggtcatcctccaagtggtcataccccggctggcggtcatttccatcaaccag
gttgtggcccaggcagtgttattcatgtgtatgaacacagctggaatcttcatcagttac
ctgtcagaccgggcccagcgccaagctttcctggagactcggaggtgtgtggaggccagg
ctgcgcctggagacagagaaccaaagacaggagcggctcgtgctttctgtgctcccccgg
tttgttgtcctggaaatgatcaacgacatgaccaatgtggaagatgagcacctgcagcac
cagttccatcggatctacatccatcgctatgagaacgtcagtattctttttgcagatgtt
aaaggatttaccaacctctccacgaccttgtctgctcaggagctggtcaggatgctcaac
gagctctttgccagatttgatcgactggcccatgagcatcactgccttcgtattaaaatc
ctgggggactgctactactgcgtgtctggacttcctgagccccgccaggaccatgcccac
tgctgtgttgaaatgggtctcagcatgatcaaaaccatcaggtatgtgcggtcaaggaca
aaacatgatgttgacatgaggattggaatccactcaggctcggtgctgtgcggtgttttg
ggactcaggaagtggcagtttgatgtctggtcttgggatgtggatattgcaaacaaactc
gaatctggaggaatccccgggaggattcacatttccaaagccacgctggactgtctcgac
ggtgactataacgtggaagagggtcatggtaaagagaggaatgaattcctgaggaagcat
aatatcgaaacttacttaattaagcagcctgaggacagtctgctgtccttgcctgaagac
atcgtcaaggagtcagtgagctcctcagaccagagaaacagtggggccacattcactgaa
ggatcctggagccctgaactgccctttgataatatcgtggggaaacagaatactctggct
gccctaacaagaaattcaataaatctgcttccaaaccatcttgcacaagctttgcatgtc
cagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggc
gataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctg
gagcacaagtattctcaaatgagggatgaagtgttcaagtcaaacttggtctgtgcattt
atcgttcttctatttatcacggcaatacaaagtttgcttccttcttcaagagtgatgcca
atgaccatccagttctccattctgattatgctgcactcggctctggtcctcatcaccaca
gcagaggattataaatgtttgcccctcatcctccggaaaacttgctgttggattaatgag
acctatttggcccggaacgtcatcatctttgcatccattttgattaatttcctgggtgcc
atcttaaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttc
aattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcacaggg
gtgttggccatggtgacctgtgcagttttcctccggctgaactctgtcctgaagctggca
gtgctgctgatcatgattgccatctatgccctgctcactgagaccgtctacgcaggcctc
tttctgcgttatgacaacctcaaccacagtggagaagatttcctggggaccaaggaggca
tcactgctactgatggccatgttcctcctggctgtgttctaccatggacagcagctggag
tacacagcccgcctggacttcctttggcgagtacaggccaaagaggagatcaatgagatg
aaggagctgagggaacacaatgagaacatgctccggaatatcttacccagccatgtggcc
cgccatttcctagaaaaggaccgagacaatgaggagctgtattctcaatcctatgatgct
gttggggtgatgtttgcctccatcccaggatttgcggacttttactctcagactgaaatg
aataaccagggagtggaatgcctgcgcttgctcaatgagatcattgctgactttgatgag
ttgcttggtgaagaccgatttcaagacattgaaaagattaagaccattggcagcacctac
atggccgtgtcaggcctgtcacctgaaaaacagcaatgtgaagacaagtggggacatttg
tgtgctctggctgacttctcactcgccctgacagaaagcatacaggagatcaacaagcat
tcattcaacaattttgaactccggattggcatcagccacggctcagtggtagctggcgtt
atcggcgctaagaaaccacagtatgacatttggggcaaaactgtgaacctggcaagccga
atggacagcacgggggttagtggccggatccaagtcccagaggagacctatctcatcctg
aaggaccagggctttgcctttgattaccgaggggagatctacgtgaagggcatcagtgaa
caggaaggaaaaatcaaaacgtactttctcctgggaagagtccaacccaacccattcatc
ttgcccccaagaagactgcctgggcagtactccctggccgcggttgtcctgggacttgtc
cagtccctcaataggcaaaggcagaagcagctactcaatgagaacaacaacacaggaatc
atcaagggtcattacaaccggcggactttgttgtcacccagcgggacggagcctggagcc
caggctgaaggcaccgacaaatctgatttgccataa
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