Pan troglodytes (chimpanzee): 467070 Help Entry 467070            CDS       T01005                                  Symbol TPH2 Name (RefSeq) tryptophan 5-hydroxylase 2   KO K00502   tryptophan 5-monooxygenase [EC:1.14.16.4] Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr00380   Tryptophan metabolism ptr00790   Folate biosynthesis ptr01100   Metabolic pathways ptr04726   Serotonergic synapse Module ptr_M00037   Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin Brite KEGG Orthology (KO) [BR:ptr00001]  09100 Metabolism   09105 Amino acid metabolism    00380 Tryptophan metabolism     467070 (TPH2)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     467070 (TPH2)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     467070 (TPH2) Enzymes [BR:ptr01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.4  tryptophan 5-monooxygenase      467070 (TPH2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Biopterin_H ACT TH_ACT Motif Other DBs NCBI-GeneID:  467070 NCBI-ProteinID:  XP_522470 Ensembl:  ENSPTRG00000044968 VGNC:  8582 UniProt:  A0A6D2W9R0 A0A2I3TG35 LinkDB All DBs Position 10:78688825..78785027 Genome browser AA seq 490 aa AA seqDB search MQPAMMMFSSKYWARRGFSLDSAVPEEHQLLGSSTLNKPNSGKNDDKGNKGSSKSETATE SGKTAVVFSLKNEVGGLVKALRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFN ELIQLLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHP GFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYL KNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQ YIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFF TIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYF VSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDA LNKMNQYLGI NT seq 1473 nt NT seq  +upstreamnt  +downstreamnt atgcagccagcaatgatgatgttttccagtaaatactgggcacggagagggttttccctg gattcagcagtgcccgaagagcatcagctacttggcagctcaacactaaataaacctaac tctggcaaaaatgacgacaaaggcaacaagggaagcagcaaaagtgaaactgctaccgaa agtggcaagacagcagttgttttctccttgaaaaatgaagttggcggactggtaaaagca ctgaggctctttcaggaaaaacgtgtcaacatggttcatattgaatccaggaaatctcgg cgaagaagttctgaggttgaaatctttgtggactgtgagtgtgggaaaacagaattcaat gagctcattcagttgctgaaatttcaaaccactattgtgacgctgaatcctccagagaat atttggacagaggaagaagagctagaggatgtgccctggttccctcggaagatctctgag ttagacaaatgctctcacagagttctcatgtatggttctgagcttgatgccgaccaccca ggatttaaggacaatgtctatcgacagagaagaaagtattttgtggatgtggccatgggt tataaatatggtcagcccattcccagggtggagtatactgaagaagaaactaaaacttgg ggtgttgtattccgggagctctccaaactctatcccactcatgcttgccgagagtatttg aaaaacttccctctgctgactaaatactgtggctacagagaggacaatgtgcctcaactc gaagatgtctccatgtttctgaaagaaaggtctggcttcacggtgaggccggtggctgga tacctgagcccacgagactttctggcaggactggcctacagagtgttccactgtacccag tacatccggcatggctcagatcccctctacaccccggaaccagacacatgccatgaactc ttgggacatgttccactacttgcggatcctaagtttgctcagttttcacaagaaataggt ctggcgtctctgggagcatcagatgaagatgttcagaaactagccacgtgctatttcttc acaatcgagtttggcctttgcaagcaagaagggcaactgcgggcatatggagcaggactc ctttcctccattggagaattaaagcatgccctttctgacaaggcatgtgtgaaagccttt gacccaaagacaacttgcttacaggaatgccttatcaccaccttccaggaagcctacttt gtttcagaaagttttgaagaagccaaagaaaagatgagggactttgcaaagtcaattacc cgtcccttctcagtatacttcaatccctacacacagagtattgaaattctgaaagacacc agaagtattgaaaatgtggtgcaggaccttcgcagcgacttgaatacagtgtgtgatgct ttaaacaaaatgaaccaatatctgggaatttga

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