Pan troglodytes (chimpanzee): 467875
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Entry
467875 CDS
T01005
Symbol
PDPK1
Name
(RefSeq) 3-phosphoinositide-dependent protein kinase 1 isoform X1
KO
K06276
3-phosphoinositide dependent protein kinase-1 [EC:
2.7.11.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01524
Platinum drug resistance
ptr03320
PPAR signaling pathway
ptr04068
FoxO signaling pathway
ptr04071
Sphingolipid signaling pathway
ptr04140
Autophagy - animal
ptr04150
mTOR signaling pathway
ptr04151
PI3K-Akt signaling pathway
ptr04152
AMPK signaling pathway
ptr04210
Apoptosis
ptr04360
Axon guidance
ptr04510
Focal adhesion
ptr04517
IgSF CAM signaling
ptr04660
T cell receptor signaling pathway
ptr04664
Fc epsilon RI signaling pathway
ptr04722
Neurotrophin signaling pathway
ptr04910
Insulin signaling pathway
ptr04919
Thyroid hormone signaling pathway
ptr04931
Insulin resistance
ptr04960
Aldosterone-regulated sodium reabsorption
ptr05145
Toxoplasmosis
ptr05205
Proteoglycans in cancer
ptr05208
Chemical carcinogenesis - reactive oxygen species
ptr05213
Endometrial cancer
ptr05215
Prostate cancer
ptr05223
Non-small cell lung cancer
ptr05231
Choline metabolism in cancer
ptr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
467875 (PDPK1)
04071 Sphingolipid signaling pathway
467875 (PDPK1)
04151 PI3K-Akt signaling pathway
467875 (PDPK1)
04152 AMPK signaling pathway
467875 (PDPK1)
04150 mTOR signaling pathway
467875 (PDPK1)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
467875 (PDPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
467875 (PDPK1)
09143 Cell growth and death
04210 Apoptosis
467875 (PDPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
467875 (PDPK1)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
467875 (PDPK1)
04664 Fc epsilon RI signaling pathway
467875 (PDPK1)
09152 Endocrine system
04910 Insulin signaling pathway
467875 (PDPK1)
03320 PPAR signaling pathway
467875 (PDPK1)
04919 Thyroid hormone signaling pathway
467875 (PDPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
467875 (PDPK1)
09156 Nervous system
04722 Neurotrophin signaling pathway
467875 (PDPK1)
09158 Development and regeneration
04360 Axon guidance
467875 (PDPK1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
467875 (PDPK1)
05208 Chemical carcinogenesis - reactive oxygen species
467875 (PDPK1)
05231 Choline metabolism in cancer
467875 (PDPK1)
09162 Cancer: specific types
05215 Prostate cancer
467875 (PDPK1)
05213 Endometrial cancer
467875 (PDPK1)
05223 Non-small cell lung cancer
467875 (PDPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
467875 (PDPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
467875 (PDPK1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
467875 (PDPK1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
467875 (PDPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
467875 (PDPK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ptr04131
]
467875 (PDPK1)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
467875 (PDPK1)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: AGC group
PDK1 family
467875 (PDPK1)
Membrane trafficking [BR:
ptr04131
]
Exocytosis
Calcium ion-dependent exocytosis
Acrosomal exocytosis proteins
467875 (PDPK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PH_3
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Pkinase_fungal
Haspin_kinase
APH
Kdo
RIO1
Motif
Other DBs
NCBI-GeneID:
467875
NCBI-ProteinID:
XP_024205812
Ensembl:
ENSPTRG00000007655
VGNC:
13762
UniProt:
K7B926
LinkDB
All DBs
Position
18:5150195..5220518
Genome browser
AA seq
556 aa
AA seq
DB search
MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK
ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET
CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN
SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD
FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA
YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD
SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE
GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQ
EVWRQRYQSHPDGAVQ
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atggccaggaccaccagccagctgtatgacgctgtgcccatccagtccagcgtggtgtta
tgttcctgcccatccccatcaatggtgaggacccagactgagtccagcacgccccctggc
attcctggtggcagcaggcagggccccgccatggacggcactgcagccgagcctcggccc
ggcgccggctccctgcagcatgcccagcctccgccgcagcctcggaagaagcggcctgag
gacttcaagtttgggaaaattcttggggaaggctctttttccacggttgtcctggctcga
gaactggcaacctccagagaatatgcgattaaaattctggagaagcgacatatcataaaa
gagaacaaggtcccgtatgtaaccagagagcgggatgtcatgtcgcgcctggatcacccc
ttctttgttaagctttacttcacatttcaggacgacgagaagctgtatttcggccttagt
tatgccaaaaatggagaactacttaaatatattcgcaaaatcggttcattcgatgagacc
tgtacccgattttacacggctgagattgtgtctgctttagagtacttgcacggcaagggc
atcattcacagggaccttaaaccggaaaacattttgttaaatgaagatatgcacatccag
atcacagattttggaacagcaaaagtcttatccccagagagcaaacaagccagggccaac
tcattcgtgggaacagcgcagtacgtttctccagagctgctcacggagaagtccgcctgt
aagagttcagacctttgggctcttggatgcataatataccagcttgtggcaggactccca
ccattccgagctggaaacgagtatcttatatttcagaagatcattaagttggaatatgac
tttccagaaaaattcttccctaaggcaagagacctcgtggagaaacttttggttttagat
gccacaaagcggttaggctgtgaggaaatggaagggtacggacctcttaaagcacacccg
ttcttcgagtccgtcacgtgggagaacctgcaccagcagacgcctccgaagctcaccgct
tacctgccggctatgtcggaagacgacgaggactgctatggcaattatgacaatctcctg
agccagtttggctgcatgcaggtgtcttcgtcctcgtcctcacactccctgtcagcctcc
gacacgggcctgccccagaggtcaggcagcaacatagagcagtacattcacgatctggac
tcgaactcctttgaactggacttacagttttccgaagatgagaagaggttgttgttggag
aagcaggctggcggaaacccttggcaccagtttgtagaaaataatttaatactaaagatg
ggcccagtggataagcggaagggtttatttgcaagacgacgacagctgttgctcacagaa
ggaccacatttatattatgtggatcctgtcaacaaagtcctgaaaggtgaaattccttgg
tcacaagaacttcgaccagaggccaagaattttaaaactttctttgtccacacgcctaac
aggacgtattatttgatggaccccagcgggaatgcacacaagtggtgcaggaagatccag
gaggtttggaggcagcgataccagagccacccggacggggctgtgcagtga
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