Pan troglodytes (chimpanzee): 470307
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Entry
470307 CDS
T01005
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X2
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04022
cGMP-PKG signaling pathway
ptr04024
cAMP signaling pathway
ptr04062
Chemokine signaling pathway
ptr04071
Sphingolipid signaling pathway
ptr04270
Vascular smooth muscle contraction
ptr04310
Wnt signaling pathway
ptr04360
Axon guidance
ptr04510
Focal adhesion
ptr04519
Cadherin signaling
ptr04520
Adherens junction
ptr04530
Tight junction
ptr04611
Platelet activation
ptr04670
Leukocyte transendothelial migration
ptr04810
Regulation of actin cytoskeleton
ptr04921
Oxytocin signaling pathway
ptr05132
Salmonella infection
ptr05135
Yersinia infection
ptr05163
Human cytomegalovirus infection
ptr05200
Pathways in cancer
ptr05205
Proteoglycans in cancer
ptr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
470307 (ROCK2)
04071 Sphingolipid signaling pathway
470307 (ROCK2)
04024 cAMP signaling pathway
470307 (ROCK2)
04022 cGMP-PKG signaling pathway
470307 (ROCK2)
09133 Signaling molecules and interaction
04519 Cadherin signaling
470307 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
470307 (ROCK2)
04520 Adherens junction
470307 (ROCK2)
04530 Tight junction
470307 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
470307 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
470307 (ROCK2)
04670 Leukocyte transendothelial migration
470307 (ROCK2)
04062 Chemokine signaling pathway
470307 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
470307 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
470307 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
470307 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
470307 (ROCK2)
05205 Proteoglycans in cancer
470307 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
470307 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
470307 (ROCK2)
05135 Yersinia infection
470307 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
470307 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
470307 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ptr03036
]
470307 (ROCK2)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
470307 (ROCK2)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
470307 (ROCK2)
Chromosome and associated proteins [BR:
ptr03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
470307 (ROCK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
APH
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
470307
NCBI-ProteinID:
XP_054534225
Ensembl:
ENSPTRG00000011658
VGNC:
6655
LinkDB
All DBs
Position
12:111531332..111696946
Genome browser
AA seq
1472 aa
AA seq
DB search
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLV
GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
LLSDSPSCRENDSIQSRKNEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKEL
EEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLK
KRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQD
KNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKILLAK
VELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYES
IEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDV
LNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLTEMKMNLEKQ
NAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQEL
QDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEK
DATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQL
LTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKY
QKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEA
DDGFPVHITQSHTMESMSFTYQRSSTSLNIATKPSSSHTLLDSDSDSEEESLPYLPISSE
PNGTESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKL
FHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGHEFIP
TLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAK
NLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPN
KPRLLDLAFKDWDWSFDDVDGGGDDDDDVFDF
NT seq
4419 nt
NT seq
+upstream
nt +downstream
nt
atgagccggcccccgccgacggggaaaatgcccggcgcccccgagaccgcgccgggggac
ggggcaggcgcgagccgccagaggaagctggaggcgctgatccgagaccctcgctccccc
atcaacgtggagagcttgctggatggcttaaattccttggtccttgatttagattttcct
gctttgaggaaaaacaagaacatagataatttcttaaatagatatgagaaaattgtgaaa
aaaatcagaggtctacagatgaaggcagaagactatgatgttgtaaaagttattggaaga
ggtgcttttggtgaagtgcagttggttcgtcacaaggcatcgcagaaggtttatgctatg
aagcttcttagtaagtttgaaatgataaaaagatcagattctgcctttttttgggaagaa
agagatattatggcctttgccaatagcccctgggtggttcagcttttttatgcctttcaa
gatgataggtatctgtacatggtaatggagtacatgcctggtggagaccttgtaaacctt
atgagtaattacgatgtgcctgaaaaatgggccaaattttacactgctgaagttgttctt
gctctggatgcaatacactccatgggtttaatacacagagatgtgaagcctgacaacatg
ctcttggataaacatggacatctaaaattagcagattttggcacgtgtatgaagatggat
gaaacaggcatggtacattgtgatacagcagttggaacaccggattatatatcacctgag
gttctgaaatcacaagggggtgatggttactatgggcgagaatgtgattggtggtctgta
ggtgttttcctttatgagatgctagtgggggatactccattttatgcggattcacttgta
ggaacatatagcaaaattatggatcataagaattcactgtgtttccctgaagatgcagaa
atttccaaacatgcaaagaatctcatctgtgctttcttaacagatagggaggtacgactt
gggagaaatggggtggaagaaatcagacagcatcctttctttaagaatgatcagtggcat
tgggataacataagagaaacggcagctcctgtagtacctgaactcagcagtgacatagac
agcagcaatttcgatgacattgaagatgacaaaggagatgtagaaaccttcccaattcct
aaagcttttgttggaaatcagctgcctttcatcggatttacctactatagagaaaattta
ttattaagtgactctccatcttgtagagaaaatgattcaatacaatcaaggaaaaatgaa
attcagaaaaaactgtatacattagaagaacatcttagcaatgagatgcaagccaaagag
gaactggaacagaagtgcaaatctgttaatactcgcctagaaaagacagcaaaggagcta
gaagaggagattaccttacggaaaagtgtggaatcagcattaagacagttagaaagagaa
aaggcgcttcttcagcacaaaaatgcagaatatcagaggaaagctgatcatgaagcagac
aaaaaacgaaatttggaaaatgatgttaacagcttaaaagatcaacttgaagatttgaaa
aaaagaaatcaaaactctcaaatatccactgagaaagtgaatcaactccagagacaactg
gatgaaaccaatgctttactgcgaacagagtctgatactgcagcccggttaaggaaaacc
caggcagaaagttcaaaacagattcagcagctggaatctaacaatagagatctacaagat
aaaaactgcctgctggagactgccaagttaaaacttgaaaaggaatttatcaatcttcag
tcagctctagaatctgaaaggagggatcgaacccatggatcagagataattaatgattta
caaggtagaatatgtggcctagaagaagatttaaagaacggcaaaatcttattagcgaaa
gtagaactggagaagagacaacttcaggagagatttactgatttggaaaaggaaaaaagc
aacatggaaatagatatgacataccaactaaaagttatacagcagagcctagaacaagaa
gaagctgaacataaggccacaaaggcacgactagcagataaaaataagatctatgagtcc
atcgaagaagccaaatcagaagccatgaaagaaatggagaagaagctcttggaggaaaga
actttaaaacagaaagtggagaacctattgctagaagctgagaaaagatgttctctatta
gactgtgacctcaaacagtcacagcagaaaataaatgagctccttaaacagaaagatgtg
ctaaatgaggatgttagaaacctgacattaaaaatagagcaagaaactcagaagcgctgc
cttacacaaaatgacctgaagatgcaaacacaacaggttaacacactaaaaatgtcagaa
aagcagttaaagcaagaaaataaccatctcacggaaatgaaaatgaacttggaaaaacaa
aatgctgaacttcgaaaagaacgtcaggatgcagatgggcaaatgaaagagctccaggat
cagctcgaagcagaacagtatttctcaaccctttataaaacacaagttagggagcttaaa
gaagaatgtgaagaaaagaccaaacttggtaaagaattgcagcagaagaaacaggaatta
caggatgaacgggactctttggctgcccaactggagatcaccttgaccaaagcagattct
gagcaactggctcgttcaattgctgaagaacaatattctgatttggaaaaagagaagatc
atgaaagagctggagatcaaagagatgatggctagacacaaacaggaacttaccgaaaaa
gatgctacaattgcttctcttgaggaaactaataggacactaactagtgatgttgccaat
cttgcaaatgagaaagaagaattaaataacaaattgaaagatgttcaagagcaactgtca
agattgaaagatgaagaaataagcgcagcagctattaaagcacagtttgagaagcagcta
ttaacagaaagaacactcaaaactcaagctgtgaataagttggctgagatcatgaatcga
aaagaacctgtcaagcgtggtaatgacacagatgtgcggagaaaagagaaggagaataga
aagctacatatggagcttaaatctgaacgtgagaaattgacccagcagatgatcaagtat
cagaaagaactgaatgaaatgcaggcacaaatagctgaagagagccagattcgaattgaa
ctgcagatgacattggacagtaaagacagtgacattgagcagctgcggtcacaactccaa
gccttgcatattggtctggatagttccagtataggcagtggaccaggggatgctgaggca
gatgatgggtttccagttcatatcactcagtcacacactatggaatccatgtcattcacc
taccagcgttcctctacttctctcaatattgccactaagccttccagttctcacacgctc
cttgactctgattctgactcagaagaagaatctttgccttacttacccatttcatcggaa
cctaatggtacagaatcaagattagaaggatggctttcattgcctgtacgaaacaacact
aagaaatttggatgggttaaaaagtatgtgattgtaagcagtaagaagattcttttctat
gacagtgaacaagataaagaacaatccaatccttacatggttttagatatagacaagtta
tttcatgtccgaccagttacacagacagatgtgtatagagcagatgctaaagaaattcca
aggatattccagattctgtatgccaatgaaggagaaagtaagaaggaacaagaatttcca
gtggagccagttggagaaaaatctaattatatttgccacaagggacatgagtttattcct
actctttatcatttcccaaccaactgtgaggcttgtatgaagcccctgtggcacatgttt
aagcctcctcctgctttggagtgccgccgttgccatattaagtgtcataaagatcatatg
gacaaaaaggaggagattatagcaccttgcaaagtatattatgatatttcaacggcaaag
aatctgttattactagcaaattctacagaagagcagcagaagtgggttagtcggttggtg
aaaaagatacctaaaaagcccccagctccagacccttttgcccgatcatctcctagaact
tcaatgaagatacagcaaaaccagtctattagacggccaagtcgacagcttgccccaaac
aaacctagattgcttgatttggcatttaaagactgggattggtcatttgatgatgttgat
ggtggtggtgatgatgatgacgatgtttttgatttctga
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integrated database retrieval system
