KEGG   Pan troglodytes (chimpanzee): 470905
Entry
470905            CDS       T01005                                 
Symbol
ADCY5
Name
(RefSeq) adenylate cyclase type 5 isoform X1
  KO
K08045  adenylate cyclase 5 [EC:4.6.1.1]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00230  Purine metabolism
ptr01100  Metabolic pathways
ptr01522  Endocrine resistance
ptr04015  Rap1 signaling pathway
ptr04022  cGMP-PKG signaling pathway
ptr04024  cAMP signaling pathway
ptr04062  Chemokine signaling pathway
ptr04072  Phospholipase D signaling pathway
ptr04081  Hormone signaling
ptr04082  Neuroactive ligand signaling
ptr04114  Oocyte meiosis
ptr04211  Longevity regulating pathway
ptr04213  Longevity regulating pathway - multiple species
ptr04261  Adrenergic signaling in cardiomyocytes
ptr04270  Vascular smooth muscle contraction
ptr04371  Apelin signaling pathway
ptr04540  Gap junction
ptr04611  Platelet activation
ptr04713  Circadian entrainment
ptr04714  Thermogenesis
ptr04723  Retrograde endocannabinoid signaling
ptr04724  Glutamatergic synapse
ptr04725  Cholinergic synapse
ptr04726  Serotonergic synapse
ptr04727  GABAergic synapse
ptr04728  Dopaminergic synapse
ptr04750  Inflammatory mediator regulation of TRP channels
ptr04911  Insulin secretion
ptr04912  GnRH signaling pathway
ptr04913  Ovarian steroidogenesis
ptr04914  Progesterone-mediated oocyte maturation
ptr04915  Estrogen signaling pathway
ptr04916  Melanogenesis
ptr04918  Thyroid hormone synthesis
ptr04921  Oxytocin signaling pathway
ptr04923  Regulation of lipolysis in adipocytes
ptr04924  Renin secretion
ptr04925  Aldosterone synthesis and secretion
ptr04926  Relaxin signaling pathway
ptr04927  Cortisol synthesis and secretion
ptr04928  Parathyroid hormone synthesis, secretion and action
ptr04934  Cushing syndrome
ptr04935  Growth hormone synthesis, secretion and action
ptr04970  Salivary secretion
ptr04971  Gastric acid secretion
ptr04972  Pancreatic secretion
ptr04976  Bile secretion
ptr05012  Parkinson disease
ptr05030  Cocaine addiction
ptr05031  Amphetamine addiction
ptr05032  Morphine addiction
ptr05034  Alcoholism
ptr05163  Human cytomegalovirus infection
ptr05166  Human T-cell leukemia virus 1 infection
ptr05200  Pathways in cancer
ptr05207  Chemical carcinogenesis - receptor activation
ptr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    470905 (ADCY5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    470905 (ADCY5)
   04371 Apelin signaling pathway
    470905 (ADCY5)
   04072 Phospholipase D signaling pathway
    470905 (ADCY5)
   04024 cAMP signaling pathway
    470905 (ADCY5)
   04022 cGMP-PKG signaling pathway
    470905 (ADCY5)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    470905 (ADCY5)
   04081 Hormone signaling
    470905 (ADCY5)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    470905 (ADCY5)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    470905 (ADCY5)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    470905 (ADCY5)
   04062 Chemokine signaling pathway
    470905 (ADCY5)
  09152 Endocrine system
   04911 Insulin secretion
    470905 (ADCY5)
   04923 Regulation of lipolysis in adipocytes
    470905 (ADCY5)
   04912 GnRH signaling pathway
    470905 (ADCY5)
   04913 Ovarian steroidogenesis
    470905 (ADCY5)
   04915 Estrogen signaling pathway
    470905 (ADCY5)
   04914 Progesterone-mediated oocyte maturation
    470905 (ADCY5)
   04921 Oxytocin signaling pathway
    470905 (ADCY5)
   04926 Relaxin signaling pathway
    470905 (ADCY5)
   04935 Growth hormone synthesis, secretion and action
    470905 (ADCY5)
   04918 Thyroid hormone synthesis
    470905 (ADCY5)
   04928 Parathyroid hormone synthesis, secretion and action
    470905 (ADCY5)
   04916 Melanogenesis
    470905 (ADCY5)
   04924 Renin secretion
    470905 (ADCY5)
   04925 Aldosterone synthesis and secretion
    470905 (ADCY5)
   04927 Cortisol synthesis and secretion
    470905 (ADCY5)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    470905 (ADCY5)
   04270 Vascular smooth muscle contraction
    470905 (ADCY5)
  09154 Digestive system
   04970 Salivary secretion
    470905 (ADCY5)
   04971 Gastric acid secretion
    470905 (ADCY5)
   04972 Pancreatic secretion
    470905 (ADCY5)
   04976 Bile secretion
    470905 (ADCY5)
  09156 Nervous system
   04724 Glutamatergic synapse
    470905 (ADCY5)
   04727 GABAergic synapse
    470905 (ADCY5)
   04725 Cholinergic synapse
    470905 (ADCY5)
   04728 Dopaminergic synapse
    470905 (ADCY5)
   04726 Serotonergic synapse
    470905 (ADCY5)
   04723 Retrograde endocannabinoid signaling
    470905 (ADCY5)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    470905 (ADCY5)
  09149 Aging
   04211 Longevity regulating pathway
    470905 (ADCY5)
   04213 Longevity regulating pathway - multiple species
    470905 (ADCY5)
  09159 Environmental adaptation
   04713 Circadian entrainment
    470905 (ADCY5)
   04714 Thermogenesis
    470905 (ADCY5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    470905 (ADCY5)
   05207 Chemical carcinogenesis - receptor activation
    470905 (ADCY5)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    470905 (ADCY5)
   05163 Human cytomegalovirus infection
    470905 (ADCY5)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    470905 (ADCY5)
  09165 Substance dependence
   05030 Cocaine addiction
    470905 (ADCY5)
   05031 Amphetamine addiction
    470905 (ADCY5)
   05032 Morphine addiction
    470905 (ADCY5)
   05034 Alcoholism
    470905 (ADCY5)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    470905 (ADCY5)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    470905 (ADCY5)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    470905 (ADCY5)
Enzymes [BR:ptr01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     470905 (ADCY5)
SSDB
Motif
Pfam: AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC HILPDA
Other DBs
NCBI-GeneID: 470905
NCBI-ProteinID: XP_016797250
Ensembl: ENSPTRG00000015304
VGNC: 53353
LinkDB
Position
2:complement(126557378..126722637)
AA seq 1260 aa
MSGSKSVSPPGYAAQKTAAPAPRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA
VTPQQQQRLASRWRSDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRRG
AASGGSTRAPPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADEVEAGAVEGG
EGSGDGGSSADSGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSS
LTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGLA
CYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALH
LAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHS
QRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSL
ASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMG
MDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKA
GRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNR
QRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLG
RAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQIT
IVPHSVFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVFT
ITLVFLAAFVNMFTCNSRDLLGCLAQEHNISTSQVNACHVAESAVNYSLGDEQGFCGSPW
PNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADLL
VTANAIDFFNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQ
ATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFS
EFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYD
KVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGN
TVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
NT seq 3783 nt   +upstreamnt  +downstreamnt
atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagaagactgcggcgccg
gcgccccggggaggccccgaacaccgctcggcgtggggcgaggccgattcccgcgcgaat
ggctacccccatgcccccgggggttctgcccgcggctccaccaagaaacccgggggggcg
gtgaccccgcagcagcagcagcgcctggccagccgctggcgcagcgacgacgacgatcct
ccgctgagcggtgatgaccccctggccgggggcttcggtttcagcttccgctccaagtcc
gcctggcaggagcgcggcggcgacgactgcggtcgcggcagccgccggcagcggcggggc
gcggccagcgggggcagcacccgggcgccccctgcgggcggcggcggcggctcggcggcg
gcggctgcctcggcgggcgggacggaggtgcgccctcgctcggtggaggtgggtctggag
gagcggcggggcaaggggcgcgcggccgacgaggtggaggccggcgccgtcgagggcggc
gaggggtccggggatggcggcagctcggcggactcgggctcgggcgcggggcccggcgcg
gtgctgtccctgggcgcctgctgcctggcgttgctgcagatattccgctccaagaagttc
ccgtcggacaaactggagcggctgtaccagcgctacttcttccgcctgaaccagagcagc
ctcaccatgctcatggccgtgctggtgctcgtgtgcctggtcatgttggccttccacgcg
gcgcggcccccgctccagctgccctacctggccgtgctggcggccgccgtcggcgtgatc
ctcatcatggctgtgctttgcaaccgcgccgccttccaccaggaccacatgggcctggcc
tgctatgcgctcatcgccgtggtgctggccgtccaggtggtgggcctgctgctgccgcag
ccacgcagcgcctctgagggcatctggtggaccgtgttcttcatctacaccatctacacg
ctgctgcccgtgcgcatgcgagccgcagtgctcagcggggtgctcctgtccgccctccac
ctggccatcgccctgcgcaccaacgcccaggaccagttcctgctgaagcagcttgtctcc
aatgttctcattttctcctgcaccaacatcgtgggtgtctgcacccactatccggctgag
gtctcccagagacaggctttccaggagacccgagagtgcatccaggcgcggctccactcg
cagcgggagaaccagcagcaggaacggctcctgctgtctgtccttccccgtcatgttgcc
atggagatgaaagcagacatcaacgccaagcaggaggatatgatgttccataagatttac
atccagaaacatgacaacgtgagcatcctgtttgctgacatcgagggcttcaccagcctg
gcgtcccagtgcactgcacaggaactggtcatgaccctcaacgagctcttcgcccgcttt
gacaagctggccgcagagaatcactgtttacgtattaagatcctcggggattgttattac
tgcgtctcggggctgcctgaagcgagggctgaccacgcccactgctgtgtggagatgggc
atggacatgatcgaggccatctcgttggtccgggaggtgacaggggtgaacgtgaacatg
cgtgtgggaattcacagcgggcgagtacactgcggtgtccttggtctcaggaagtggcag
ttcgacgtctggtctaacgatgtcacgctagccaaccacatggaggctggcggcaaggcg
ggacgcatccacatcaccaaggctacactcaactacctgaatggggactacgaggtggag
ccaggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgagaccttcctc
atcctgcgctgcacccagaagcggaaagaagagaaggccatgatcgccaagatgaaccgc
cagagaaccaactccatcgggcacaacccaccacactggggggctgagcgccccttctac
aaccacctgggtggcaaccaggtgtccaaggagatgaagcggatgggctttgaagacccc
aaggacaagaacgcccaggagagtgcgaaccctgaggatgaagtggatgagtttctgggc
cgtgccattgacgccaggagcatcgataggcttcggtctgagcacgtccgcaagttcctc
ctgaccttcagggagcctgacttagagaagaagtactccaagcaggtagacgaccgattt
ggtgcctatgtggcgtgtgcctcgctcgtcttcctcttcatctgctttgtccagatcacc
atcgtgccccactccgtattcatgctcagcttctacctgacctgttccctgctgctgacc
ttggtggtgtttgtgtctgtgatctactcctgcgtaaagctcttcccctccccactgcag
accctctccaggaagatcgtgcggtccaagatgaacagcaccctggttggggtgttcacc
atcaccctggtgttcctggcggcttttgtcaacatgttcacgtgcaactccagggacctg
ctgggctgcttggcacaggagcacaacatcagcacgagccaggtcaacgcgtgtcacgtg
gcggagtcggccgtcaactacagcctgggcgatgagcagggcttctgtggcagcccctgg
cccaactgcaacttccccgagtacttcacctacagcgtgctgctcagcctgctggcctgc
tccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctc
atctacgtgctcatcgtggaggtgccaggtgtcacgctcttcgacaacgccgacctgctg
gtcaccgccaacgccatagacttcttcaacaacgggacctcccagtgccctgagcacgca
accaaggtggcattgaaggtggtgacgcccatcatcatctcagtctttgtgctggccctg
tacctgcacgcccagcaggtggagtccactgcccgcctcgacttcctctggaaactgcag
gccacagaggagaaagaggagatggaggagctgcaggcctacaaccggcggctgctgcac
aacatcctgcccaaggacgtggccgctcacttcctggcccgcgagcggcgcaatgatgag
ctctactatcagtcctgtgagtgtgtggcggtcatgttcgcctccatcgccaacttctcc
gagttctacgttgagctggaggccaacaacgagggtgtcgagtgcctgcggctactcaat
gagatcatcgctgactttgatgagatcatcagcgaggatcggttccggcagctggagaag
atcaagaccatcggcagcacctacatggctgcctccggcctcaacgactctacctacgac
aaggtgggcaagacccacatcaaggcactggccgactttgccatgaagctgatggaccag
atgaagtacatcaatgagcactccttcaacaacttccagatgaagatcgggctcaacatc
ggccccgtggtggccggggtgataggggcacgaaagcctcagtacgacatctggggcaat
accgtgaacgtggccagccgcatggacagcactggtgtacccgaccgcatccaggtcacc
acagacatgtaccaggtgctggctgccaacacgtaccagctggagtgccggggcgtggtc
aaggtcaagggcaaaggcgagatgatgacctacttcctcaatggagggcccccgctcagt
tag

DBGET integrated database retrieval system