KEGG   Pan troglodytes (chimpanzee): 735442
Entry
735442            CDS       T01005                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00670  One carbon pool by folate
ptr00790  Folate biosynthesis
ptr01100  Metabolic pathways
ptr01240  Biosynthesis of cofactors
ptr01523  Antifolate resistance
ptr04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    735442 (DHFR)
   00670 One carbon pool by folate
    735442 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    735442 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    735442 (DHFR)
Enzymes [BR:ptr01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     735442 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 735442
NCBI-ProteinID: XP_009447211
Ensembl: ENSPTRG00000017042
VGNC: 3967
UniProt: A0A6D2W2T3 H2QR61
LinkDB
Position
4:35405217..35433624
AA seq 187 aa
MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS
IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELASKVDMVWIVGGSS
VYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttggttcgctaaactgcatcgtcgctgtgtcccagaacatgggcatcggcaagaac
ggggacctgccctggccaccgctcaggaatgaattcagatatttccagagaatgaccaca
acctcttcagtagaaggtaaacagaatctggtgattatgggtaagaagacctggttctcc
attcctgagaagaatcgacctttaaagggtagaattaatttagttctcagcagagaactc
aaggaacctccacaaggagctcattttctttccagaagtctagatgatgccttaaaactt
actgaacaaccagaattagcaagtaaagtagacatggtctggatagttggtggcagttct
gtttataaggaagccatgaatcacccaggccatcttaaactatttgtgacaaggatcatg
caagactttgaaagtgacacgttttttccagaaattgatttggagaaatataaacttctg
ccagaatacccaggtgttctctctgatgtccaggaggagaaaggcattaagtacaaattt
gaagtatatgagaagaatgattaa

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