KEGG   Pan troglodytes (chimpanzee): 735881
Entry
735881            CDS       T01005                                 
Symbol
CYP1A2
Name
(RefSeq) cytochrome P450 1A2
  KO
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00140  Steroid hormone biosynthesis
ptr00232  Caffeine metabolism
ptr00380  Tryptophan metabolism
ptr00591  Linoleic acid metabolism
ptr00830  Retinol metabolism
ptr00980  Metabolism of xenobiotics by cytochrome P450
ptr00982  Drug metabolism - cytochrome P450
ptr01100  Metabolic pathways
ptr05204  Chemical carcinogenesis - DNA adducts
ptr05207  Chemical carcinogenesis - receptor activation
ptr05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    735881 (CYP1A2)
   00591 Linoleic acid metabolism
    735881 (CYP1A2)
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    735881 (CYP1A2)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    735881 (CYP1A2)
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    735881 (CYP1A2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    735881 (CYP1A2)
   00982 Drug metabolism - cytochrome P450
    735881 (CYP1A2)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    735881 (CYP1A2)
   05207 Chemical carcinogenesis - receptor activation
    735881 (CYP1A2)
   05208 Chemical carcinogenesis - reactive oxygen species
    735881 (CYP1A2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ptr00199]
    735881 (CYP1A2)
Enzymes [BR:ptr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     735881 (CYP1A2)
Cytochrome P450 [BR:ptr00199]
 Cytochrome P450, animal type
  CYP1 family
   735881 (CYP1A2)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 735881
NCBI-ProteinID: XP_016782686
Ensembl: ENSPTRG00000007281
VGNC: 13404
UniProt: A0A2I3S1F1
LinkDB
Position
16:66713212..66721021
AA seq 517 aa
MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKN
PHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDG
QSMTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAEALISRLQELM
AGPGHFDPYNQVVMSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFP
ILRYLPNPALQRFKAFNQRFLRFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGG
DLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRL
SDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFINQWQVNHDPE
LWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEVFLFLAILLQQL
EFSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN
NT seq 1554 nt   +upstreamnt  +downstreamnt
atggcattgtcccagtctgttcccttctcggccacagagcttctcctggcctctgccatc
ttctgcctggtattctgggtgctcaagggtttgaggcctcgggtccccaaaggcctgaaa
agtccaccagagccatggggctggcccttgctcgggcatgtgctgaccctggggaagaac
ccgcacctggcactgtcaaggatgagccagcgctacggggacgtgctgcagatccgcatt
ggctccacgcccgtgctggtgctgagccgcctggacaccatccggcaggccctggtgcgg
cagggcgacgatttcaagggccggcctgacctctacacctccaccctcatcactgatggc
cagagcatgaccttcagcacagactctggaccggtgtgggctgcccgccggcgcctggcc
cagaacgccctcaacaccttctccatcgcctctgacccagcttcctcatcctcctgctac
ctggaggagcatgtgagcaaggaggctgaggccctgatcagcaggttgcaggagctgatg
gcagggcctgggcacttcgacccttacaatcaggtggtgatgtcagtggccaacgtcatc
ggtgccatgtgcttcggacagcacttccctgagagtagtgatgagatgctcagcctcgtg
aagaacactcatgagttcgtggagactgcctcctccgggaaccccctggacttcttcccc
atccttcgctacctgcctaaccctgccctgcagaggttcaaggccttcaaccagaggttc
ctgcggttcctgcagaaaacagtccaggagcactatcaggactttgacaagaacagtgtc
cgggacatcacgggtgccctgttcaagcacagcaagaaggggcctagagccagcggcggc
gacctcatcccacaggagaagattgtcaaccttgtcaatgacatctttggagcaggattt
gacacagtcacaacagccatctcctggagcctcatgtaccttgtgaccaagcctgagata
cagaggaagatccagaaggagctggacactgtgattggcagggagcggcggccccggctc
tctgacagaccccagctgccctacttggaggccttcatcctggagaccttccgacactcc
tccttcttgcccttcaccatcccccacagcacaacaagggacacaacgctgaatggcttc
tacatccccaagaaatgctgtgtcttcataaaccagtggcaggtcaaccatgacccagag
ctgtgggaggacccctctgagttccggcctgagcggttcctcaccgccgatggcactgcc
attaacaagcccttgagtgagaagatgatgctgtttggcatgggcaagcgccggtgtatc
ggggaagtcctggccaagtgggaggtcttcctcttcctggccatcctgctacagcaactg
gagttcagcgtgccaccgggcgtgaaagtcgacctgacccccatctacgggctgaccatg
aagcacgcccgctgtgaacacgtccaggcgcggctgcgcttctccatcaactga

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