Pan troglodytes (chimpanzee): 743740
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Entry
743740 CDS
T01005
Symbol
SRD5A1
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X1
KO
K12343
3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:
1.3.1.22
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00140
Steroid hormone biosynthesis
ptr01100
Metabolic pathways
Module
ptr_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
ptr_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
743740 (SRD5A1)
Enzymes [BR:
ptr01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
743740 (SRD5A1)
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Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
743740
NCBI-ProteinID:
XP_001144570
Ensembl:
ENSPTRG00000016716
VGNC:
7155
UniProt:
H2QQM0
A0A6D2W9I8
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Position
4:7304604..7339918
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AA seq
259 aa
AA seq
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MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQE
LPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMA
IMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGD
TGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWY
LRKFEEYPKFRKIIIPFLF
NT seq
780 nt
NT seq
+upstream
nt +downstream
nt
atggcaacggcgacgggggtggcggaggagcgcctgctggccgcgctcgcctacctgcag
tgcgccgtgggctgcgcggtcttcgcgcggaatcgtcagacgaactcagtgtacggccgc
cacgcgctgcccagccacaggctccgagtgccagcgcgggccgcctgggtggtgcaggag
ctgccctcgctggccctgccgctctaccagtacgccagcgagtccgccccgcgtctccgc
agcgcgcccaactgcatcctcctggccatgttcctcgtccactacgggcatcggtgctta
atttacccatttctgatgcgaggaggaaagcctatgccactgttggcgtgtacaatggcg
attatgttctgtacctgtaacggctatttgcaaagcagatacttgagccattgtgcagtg
tatgctgatgactgggtaacagatccccgttttttaataggttttggcttgtggttaacg
ggcatgttgataaacatccattcagatcatatcctaaggaatctcagaaaaccaggagat
actggatacaaaataccaaggggaggcttatttgaatacgtaactgcagccaactatttt
ggagaaatcatggagtggtgtggctatgccctggccagctggtctgtccaaggcgcggct
tttgctttcttcacgttttgttttttatctggtagagcaaaagagcatcatgagtggtac
ctccggaaatttgaagagtatccaaagttcagaaaaattataattccatttttgttttaa
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