Pan troglodytes (chimpanzee): 746477 Help Entry 746477            CDS       T01005                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X9   KO K04398   caspase 8 [EC:3.4.22.61] Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr01524   Platinum drug resistance ptr04115   p53 signaling pathway ptr04210   Apoptosis ptr04215   Apoptosis - multiple species ptr04217   Necroptosis ptr04620   Toll-like receptor signaling pathway ptr04621   NOD-like receptor signaling pathway ptr04622   RIG-I-like receptor signaling pathway ptr04623   Cytosolic DNA-sensing pathway ptr04625   C-type lectin receptor signaling pathway ptr04657   IL-17 signaling pathway ptr04668   TNF signaling pathway ptr04932   Non-alcoholic fatty liver disease ptr04936   Alcoholic liver disease ptr05010   Alzheimer disease ptr05016   Huntington disease ptr05022   Pathways of neurodegeneration - multiple diseases ptr05132   Salmonella infection ptr05134   Legionellosis ptr05142   Chagas disease ptr05145   Toxoplasmosis ptr05152   Tuberculosis ptr05160   Hepatitis C ptr05161   Hepatitis B ptr05162   Measles ptr05163   Human cytomegalovirus infection ptr05164   Influenza A ptr05165   Human papillomavirus infection ptr05167   Kaposi sarcoma-associated herpesvirus infection ptr05168   Herpes simplex virus 1 infection ptr05169   Epstein-Barr virus infection ptr05170   Human immunodeficiency virus 1 infection ptr05200   Pathways in cancer ptr05203   Viral carcinogenesis ptr05416   Viral myocarditis ptr05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ptr00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     746477 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     746477 (CASP8)    04215 Apoptosis - multiple species     746477 (CASP8)    04217 Necroptosis     746477 (CASP8)    04115 p53 signaling pathway     746477 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     746477 (CASP8)    04621 NOD-like receptor signaling pathway     746477 (CASP8)    04622 RIG-I-like receptor signaling pathway     746477 (CASP8)    04623 Cytosolic DNA-sensing pathway     746477 (CASP8)    04625 C-type lectin receptor signaling pathway     746477 (CASP8)    04657 IL-17 signaling pathway     746477 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     746477 (CASP8)    05203 Viral carcinogenesis     746477 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     746477 (CASP8)    05161 Hepatitis B     746477 (CASP8)    05160 Hepatitis C     746477 (CASP8)    05164 Influenza A     746477 (CASP8)    05162 Measles     746477 (CASP8)    05168 Herpes simplex virus 1 infection     746477 (CASP8)    05163 Human cytomegalovirus infection     746477 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     746477 (CASP8)    05169 Epstein-Barr virus infection     746477 (CASP8)    05165 Human papillomavirus infection     746477 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     746477 (CASP8)    05134 Legionellosis     746477 (CASP8)    05152 Tuberculosis     746477 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     746477 (CASP8)    05142 Chagas disease     746477 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     746477 (CASP8)    05016 Huntington disease     746477 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     746477 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     746477 (CASP8)    05416 Viral myocarditis     746477 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     746477 (CASP8)    04932 Non-alcoholic fatty liver disease     746477 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     746477 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ptr01002]     746477 (CASP8) Enzymes [BR:ptr01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      746477 (CASP8) Peptidases and inhibitors [BR:ptr01002]  Cysteine peptidases   Family C14: caspase family    746477 (CASP8) SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN DUF8196 Motif Other DBs NCBI-GeneID:  746477 NCBI-ProteinID:  XP_001172193 Ensembl:  ENSPTRG00000012801 VGNC:  119 UniProt:  H2QJ86 A0A6D2WT42 LinkDB All DBs Position 13:103265594..103320609 Genome browser AA seq 538 aa AA seqDB search MEGGRRARVVIESKRNFFLGAFPTPFPAEHVELGRLGDSETAMVPGKGGADYILLPFKKM DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK FLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINRSLLKIINDYEEF SKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINN HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVQQIYEILKIYQL MDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQ GDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWY IQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD NT seq 1617 nt NT seq  +upstreamnt  +downstreamnt atggagggaggcagaagagccagggtggttattgaaagtaaaagaaacttcttcctggga gcctttcccacccccttccctgctgagcacgtggagttaggcaggttaggggactcggag actgcgatggtgccaggaaagggtggagcggattatattctcctgccttttaaaaagatg gacttcagcagaaatctttatgatattggggaacaactggacagtgaagatctggcctcc ctcaagttcctgagcctggactacattccgcaaaggaagcaagaacccatcaaggatgcc ttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaatctgtccttc ctgaaggagctgctcttccgaattaatagactggatttgctgattacctacctaaacact agaaaggaggagatggaaagggaacttcagacaccaggcagggctcaaatttctgcctac agggtcatgctgtatcagatttcagaagaagtgagcagatcagaattgaggtcttttaag tttcttttgcaagaggaaatctccaaatgcaaactggatgatgacatgaacctgctggat attttcatagagatggagaagagggtcatcctgggagaaggaaagttggacatcctgaaa agagtctgtgcccaaatcaacaggagcctgctgaagataatcaacgactatgaagaattc agcaaagagagaagcagcagccttgaaggaagtcctgatgaattttcaaatggggaggag ttgtgtggggtaatgacaatctcggactctccaagagaacaggatagtgaatcacagact ttggacaaagtttaccaaatgaaaagcaaacctcggggatactgtctgatcatcaacaat cacaattttgcaaaagcacgggagaaagtgcccaaacttcacagcattagggacaggaat ggaacacacttggatgcaggggctttgaccacgacctttgaagagcttcattttgagatc aagccccacgatgactgcacggtacagcaaatctatgagattttgaaaatctaccaactc atggaccacagtaacatggactgcttcatctgctgtatcctctcccatggagacaagggc atcatctacggcactgatggacaggaggcccccatctatgagctgacatctcagttcact ggtttgaagtgcccttcccttgctggaaaacccaaagtgttttttattcaggcttgtcag ggggataactaccagaaaggtatacctgttgagactgattcagaggagcaaccctattta gaaatggatttatcatcacctcaaacgagatatatcccggatgaggctgactttctgctg gggatggccactgtgaataactgtgtttcctaccgaaaccctgcagagggaacctggtac atccagtcactttgccagagcctgagagagcgatgtcctcgaggcgatgatattctcacc atcctgactgaagtgaactatgaagtaagcaacaaggatgacaagaaaaacatggggaaa cagatgcctcagcctactttcacactaagaaaaaaacttgtcttcccttctgattga

DBGET integrated database retrieval system