Panthera uncia (snow leopard): 125911546 Help Entry 125911546         CDS       T08832                                  Name (RefSeq) tyrosine 3-monooxygenase   KO K00501   tyrosine 3-monooxygenase [EC:1.14.16.2] Organism puc  Panthera uncia (snow leopard) Pathway puc00350   Tyrosine metabolism puc00790   Folate biosynthesis puc01100   Metabolic pathways puc04728   Dopaminergic synapse puc04917   Prolactin signaling pathway puc05012   Parkinson disease puc05030   Cocaine addiction puc05031   Amphetamine addiction puc05034   Alcoholism Module puc_M00042   Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline Brite KEGG Orthology (KO) [BR:puc00001]  09100 Metabolism   09105 Amino acid metabolism    00350 Tyrosine metabolism     125911546   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     125911546  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     125911546   09156 Nervous system    04728 Dopaminergic synapse     125911546  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     125911546   09165 Substance dependence    05030 Cocaine addiction     125911546    05031 Amphetamine addiction     125911546    05034 Alcoholism     125911546 Enzymes [BR:puc01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.2  tyrosine 3-monooxygenase      125911546 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Biopterin_H TH_ACT TOH_N LTP_2 Motif Other DBs NCBI-GeneID:  125911546 NCBI-ProteinID:  XP_049471474 LinkDB All DBs Position D1:complement(733554..740908) Genome browser AA seq 494 aa AA seqDB search MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREKAEAAGATSS EPGDPLETAVFKEKDGKATLNLIFTLRGAKASLSRAVKAFETFEAQIRHLETRPAQRPRA GGPHLEYFVCCEVPSADLPALLSSVRRVAEDVRGARENKVFWFPRKVSELDKCHHLVTKF DPDLDLGHPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKGLY VTHACREHLEAFQLLERFSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASL AFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEI EKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQ DQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRSLQGVQ DELHTLTHALSAIG NT seq 1485 nt NT seq  +upstreamnt  +downstreamnt atgcccactcccaacgccgcctcgccgcaggccaagggcttccgcagggccgtctccgag ctggacgccaagcaggccgaagccatcatgtccccgcgcttcatcgggcgacggcagagc ctcatcgaggacgctcgcaaggagcgagagaaggcagaggccgcgggggccacctcctcg gagcccggggaccccctggagaccgcagtgttcaaggagaaggacggaaaggccacgctc aacttgatcttcaccctgcggggcgccaaagcctcactgtcccgggccgtgaaggcgttc gagacgtttgaggcccaaatccggcacctggagacccggccggcccagaggccgcgcgca gggggcccccacctggaatacttcgtgtgctgtgaggtgcccagcgcggacctgcccgcc ctgctcagctccgtgcgccgggtggctgaggacgtgcggggcgccagggagaacaaggtc ttctggttcccaaggaaagtttccgagctggacaagtgccaccacctggtcaccaagttt gaccctgacctggacttgggtcacccgggtttctcggaccaggcgtaccggcagcgcagg aagctgatcgccgagatagccttccagtacaagcatggtgaccccattccccgtgtggag tacacggccgaggagatcgccacctggaaggaggtctacaccaccctcaagggcctctac gtcactcacgcctgccgggaacacctggaggctttccagctgctggagcgtttcagcggg taccgggaggacagcatccctcagctggaagacgtgtcccgcttcctgaaggagcggaca gggttccagctgcggcccgtggccggcctgctgtccgcccgggacttcctggccagcctg gcctttcgagtgttccagtgcacccagtacatccgacacgcctcctcgcccatgcactcc ccggagccggactgctgccacgagctgctggggcacgtgcccatgctggccgaccggacc ttcgctcagttctcccaggacatcgggctcgcgtccttgggggcttccgacgaggagatt gagaagctgtccacgctgtactggttcacggtggagttcgggctgtgcaagcagaatggg gaggtgaaggcctacggtgctggactgctgtcctcctacggggagctcctgcactctctg tctgaggagcccgagatccgggccttcgacccggatgctgcagccgtacagccttaccag gaccagacttaccagcccgtctacttcgtgtccgagagtttcagcgacgccaaggacaaa ctcaggaactatgcttcccgcatccagcgccccttctccgtgaagtttgacccgtacacg ctggccatcgacgtgctggacagtccccatgccatccggcgctccctgcagggcgtccag gacgagctacacaccctcacccatgcgctgagcgccatcggctag

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