Entry Name Steroid degradation - Pseudoalteromonas viridis
Class Metabolism; Xenobiotics biodegradation and metabolismBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Pseudoalteromonas viridis [GN:
pvb ]
Gene Compound C00674 5alpha-Androstane-3,17-dione
C04793 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione
C04844 3-Hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate
C11354 2-Hydroxy-cis-hex-2,4-dienoate
C14909 9alpha-Hydroxyandrosta-1,4-diene-3,17-dione
C19944 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione
C20144 Androsta-1,4-diene-3,17-dione
C20199 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate
C20252 5-Androstene-3,17-dione
C20838 3-[(3aS,4S,7aS)-7a-Methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA
C20839 (25R)-3-Oxocholest-4-en-26-oate
C21076 Delta4-Dafachronic acid
Reference Authors Ouellet H, Johnston JB, de Montellano PR
Title Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.
Journal Reference Authors Van der Geize R, Yam K, Heuser T, Wilbrink MH, Hara H, Anderton MC, Sim E, Dijkhuizen L, Davies JE, Mohn WW, Eltis LD
Title A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages.
Journal Reference Authors Thomas ST, VanderVen BC, Sherman DR, Russell DG, Sampson NS
Title Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism.
Journal Reference Authors Driscoll MD, McLean KJ, Levy C, Mast N, Pikuleva IA, Lafite P, Rigby SE, Leys D, Munro AW
Title Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen.
Journal Reference Authors Johnston JB, Ouellet H, Ortiz de Montellano PR
Title Functional redundancy of steroid C26-monooxygenase activity in Mycobacterium tuberculosis revealed by biochemical and genetic analyses.
Journal Reference Authors Yang X, Dubnau E, Smith I, Sampson NS
Title Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase.
Journal Reference Authors Lack NA, Yam KC, Lowe ED, Horsman GP, Owen RL, Sim E, Eltis LD
Title Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism.
Journal Reference Authors Kreit J, Sampson NS
Title Cholesterol oxidase: physiological functions.
Journal Reference Authors Horinouchi M, Hayashi T, Kudo T
Title Steroid degradation in Comamonas testosteroni.
Journal Reference Authors Horinouchi M, Kurita T, Hayashi T, Kudo T
Title Steroid degradation genes in Comamonas testosteroni TA441: Isolation of genes encoding a Delta4(5)-isomerase and 3alpha- and 3beta-dehydrogenases and evidence for a 100 kb steroid degradation gene hot spot.
Journal KO pathway LinkDB All DBs
