KEGG   PATHWAY: pxn00740
Entry
pxn00740                    Pathway                                
Name
Riboflavin metabolism - Pseudomonas xantholysinigenes
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
pxn00740  Riboflavin metabolism
pxn00740

Module
pxn_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:pxn00740]
Other DBs
GO: 0006771
Organism
Pseudomonas xantholysinigenes [GN:pxn]
Gene
HU772_015180  GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
HU772_002800  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
HU772_002770  ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase [KO:K14652] [EC:4.1.99.12 3.5.4.25]
HU772_015165  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
HU772_002760  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
HU772_000720  HAD family hydrolase [KO:K20862] [EC:3.1.3.102 3.1.3.104]
HU772_002850  ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase [KO:K02858] [EC:4.1.99.12]
HU772_002775  ribE; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
HU772_002765  riboflavin synthase [KO:K00793] [EC:2.5.1.9]
HU772_003765  ribF; bifunctional riboflavin kinase/FAD synthetase [KO:K11753] [EC:2.7.1.26 2.7.7.2]
HU772_013880  msuE; FMN reductase [KO:K00299] [EC:1.5.1.38]
HU772_023900  ssuE; NADPH-dependent FMN reductase [KO:K00299] [EC:1.5.1.38]
HU772_006285  bluB; 5,6-dimethylbenzimidazole synthase [KO:K04719] [EC:1.13.11.79]
HU772_022440  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HU772_002950  ubiX; flavin prenyltransferase UbiX [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
PMID:12136096
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
PMID:11856310
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
PMID:12867427
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
PMID:16042598
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
pxn00030  Pentose phosphate pathway
pxn00040  Pentose and glucuronate interconversions
pxn00230  Purine metabolism
pxn00860  Porphyrin metabolism
pxn00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

DBGET integrated database retrieval system