KEGG   PATHWAY: pxn00230
Entry
pxn00230                    Pathway                                
Name
Purine metabolism - Pseudomonas xantholysinigenes
Class
Metabolism; Nucleotide metabolism
Pathway map
pxn00230  Purine metabolism
pxn00230

Module
pxn_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pxn00230]
pxn_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pxn00230]
pxn_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pxn00230]
pxn_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pxn00230]
pxn_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pxn00230]
pxn_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pxn00230]
pxn_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pxn00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas xantholysinigenes [GN:pxn]
Gene
HU772_022440  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HU772_001195  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
HU772_013440  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
HU772_024340  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
HU772_021045  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
HU772_007765  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
HU772_021950  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
HU772_006230  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
HU772_019375  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
HU772_019570  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
HU772_006235  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
HU772_024585  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
HU772_024590  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
HU772_018235  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HU772_009945  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HU772_021945  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
HU772_016655  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
HU772_014855  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
HU772_018850  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HU772_001190  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
HU772_016570  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
HU772_003840  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
HU772_020935  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
HU772_019695  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
HU772_020405  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HU772_023345  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
HU772_024230  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
HU772_016735  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
HU772_016740  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
HU772_019690  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
HU772_016750  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
HU772_024395  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
HU772_006075  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
HU772_006065  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HU772_008100  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
HU772_013000  dgt; dNTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
HU772_024425  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
HU772_023985  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HU772_006205  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
HU772_000770  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
HU772_022280  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
HU772_003160  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
HU772_014845  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
HU772_021685  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
HU772_019150  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
HU772_006210  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
HU772_022430  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
HU772_002150  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
HU772_004505  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
HU772_004495  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
HU772_016770  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
HU772_016780  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
HU772_016935  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
HU772_016775  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
HU772_014015  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
HU772_016785  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
HU772_014130  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
HU772_014135  urease subunit beta [KO:K01429] [EC:3.5.1.5]
HU772_014140  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
HU772_019860  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pxn00030  Pentose phosphate pathway
pxn00220  Arginine biosynthesis
pxn00250  Alanine, aspartate and glutamate metabolism
pxn00260  Glycine, serine and threonine metabolism
pxn00340  Histidine metabolism
pxn00630  Glyoxylate and dicarboxylate metabolism
pxn00730  Thiamine metabolism
pxn00740  Riboflavin metabolism
pxn00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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