Rousettus aegyptiacus (Egyptian rousette): 107513264
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Entry
107513264 CDS
T06036
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00350
Tyrosine metabolism
ray00790
Folate biosynthesis
ray01100
Metabolic pathways
ray04728
Dopaminergic synapse
ray04917
Prolactin signaling pathway
ray05012
Parkinson disease
ray05030
Cocaine addiction
ray05031
Amphetamine addiction
ray05034
Alcoholism
Module
ray_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
107513264 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
107513264 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
107513264 (TH)
09156 Nervous system
04728 Dopaminergic synapse
107513264 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
107513264 (TH)
09165 Substance dependence
05030 Cocaine addiction
107513264 (TH)
05031 Amphetamine addiction
107513264 (TH)
05034 Alcoholism
107513264 (TH)
Enzymes [BR:
ray01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
107513264 (TH)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Pollen_allerg_2
Motif
Other DBs
NCBI-GeneID:
107513264
NCBI-ProteinID:
XP_036077099
LinkDB
All DBs
Position
Unknown
AA seq
521 aa
AA seq
DB search
MPTSNPAAPQPKGFRRAVSELDAKQAEAIMVRGPAGQPGPTLAGLPWGRADPAASPQTPR
FVGRRQSLIEDARKEREKAEAQAAAAEPGEPLVAGACVDRDGKAVLALLFSLRGDKPAPL
SRALKAFEAFEAQIQHLETRPARRPRAGGPQLEYFVRCEVPSADLPALLSSVRRVAEDVR
GAGENKVLWFPRKASELDKCHHLVTKFDPDLDLDHPGFSDQLYRARRRQIAQIAFQYQHG
DPIPRVEYTAEEIATWKEVYGTLRGLYATHACREHLEAFALLERFCGYAEDSIPQLEDVS
RFLKERSGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHV
PMLADRSFAQFSQDIGLASLGASDEEIERLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSY
GELLHSLSEEPEVRPFDPDAAAVQPYQDQTYQPVYFLSDSFGDAREKLRSYASRIQRPFS
VKFDPYTLAIDVLDSPHAIRRSLEQVQDELHTLATALSAIG
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgcccacctccaaccccgccgcaccgcagcccaagggtttccgcagggccgtctccgag
ctggacgccaagcaggctgaggccatcatggtaagggggccggcgggacagcctggcccc
acgctcgctggccttccctggggccgggctgacccggccgcgtccccacagaccccgcgc
ttcgtgggccggaggcagagcctcatcgaggatgcccgcaaggagcgtgagaaggcggag
gcccaggccgcggcggcggagcccggggagcccctggtggccggggcgtgcgtggacagg
gacggcaaggccgtgctggccctgctcttcagcctgcggggtgacaagcccgccccgctg
tctcgagccctgaaggcattcgaggccttcgaagcccagatccagcacctggagacccgg
cccgcccggaggccgcgggcggggggcccccagctggagtacttcgtccgctgtgaggtg
cccagcgccgacctgcccgccctgctcagctccgtgcgccgggtggcggaggacgtgcgt
ggtgccggggagaacaaggtcctctggttcccaaggaaagcctccgagctggacaagtgt
caccacctggtcaccaagttcgaccctgacctggacttggatcatccgggcttctccgac
cagctgtaccgcgctcgccggcggcagatcgcccagatcgcgttccagtaccagcacggt
gaccctattcctcgtgtggagtacacggcagaggagatcgccacctggaaggaggtgtac
ggcacgctgaggggcctgtacgccacacacgcctgccgggagcacctggaggcgttcgcg
ctgctggagcgcttctgcggctacgcggaggacagcatcccgcagctggaggacgtgtcc
cgcttcctgaaggagcggtcgggcttccagctgcggcccgtggccggcctgctgtccgct
cgcgacttcctggccagcctggccttccgcgtgttccagtgcacgcagtacatccgccac
gcctcctcgcccatgcactcccccgagccggactgctgtcacgagctgctgggccacgtg
cccatgctggccgaccggagcttcgcccagttctcccaggacattggcctggcgtccctg
ggagcctcggacgaggaaatcgagaggctgtccacgctgtactggttcacggtggagttt
gggttgtgcaagcagaacggggaggtgaaggcctacggagccgggctgctgtcgtcctac
ggggagctcctgcactcgctgtcggaggagcccgaggtgcggccgttcgacccggacgcg
gcggcggtgcagccttaccaggaccagacgtaccagccggtgtacttcctgtcggacagc
ttcggcgacgcccgcgagaagctcaggagctacgcctcccgcatccagcgccccttctcc
gtgaagttcgacccgtacacgctggcaatcgacgtgctggacagcccccacgccatccgc
cgctccttggagcaagtgcaggacgagctgcacaccctcgccactgcgctcagcgccatt
ggctag
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