PATHWAY: rn00624 Help
Entry Name Polycyclic aromatic hydrocarbon degradation
Class Metabolism; Xenobiotics biodegradation and metabolism
Pathway map rn00624 Polycyclic aromatic hydrocarbon degradation
Module M00623 Phthalate degradation, phthalate => protocatechuate [PATH:rn00624 ]
M00624 Terephthalate degradation, terephthalate => 3,4-dihydroxybenzoate [PATH:rn00624 ]
M00636 Phthalate degradation, phthalate => protocatechuate [PATH:rn00624 ]
Other DBs Reaction R00818 salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)
R01628 3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)
R01631 protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)
R01632 protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)
R01633 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase
R01634 3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
R01635 4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
R03630 phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating)
R03692 dihydrocoumarin lactonohydrolase
R04151 (+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase
R05148 benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R05275 cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase
R05375 4-hydroxyphthalate carboxy-lyase
R05422 fluorene,NADH:oxygen oxidoreductase
R05632 1-hydroxy-2-naphthoate,NADH:oxygen oxidoreductase (2-hydroxylating, decarboxylating)
R05643 2-formylbenzoate:NAD+ oxidoreductase
R05653 phenanthrene 9,10-monooxygenase
R05654 phenanthrene 1,2-monooxygenase
R07657 1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing)
R07703 1,2-dihydrophthalic acid:NAD+ oxidoreductase
R07704 anthracene,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R07705 anthracene cis-1,2-dihydrodiol:NAD+ 1,2-oxidoreductase
R07713 (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase (pyruvate-forming)
R09162 cis-4,5-dihydroxy-4,5-dihydropyrene:NAD+ 4,5-oxidoreductase
R09184 9,10-dihydroxybenzo[a]pyrene:oxygen 10,10a-oxidoreductase (decyclizing)
R11540 poly(ethylene terephthalate) hydrolase
R11541 4-[(2-hydroxyethoxy)carbonyl]benzoate acylhydrolase
Compound C01163 3-Carboxy-cis,cis-muconate
C01198 3-(2-Hydroxyphenyl)propanoate
C04468 (+)-cis-3,4-Dihydrophenanthrene-3,4-diol
C04484 4-Carboxy-2-hydroxymuconate semialdehyde
C04783 cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate
C06318 (3S,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate
C07718 2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic acid
C07721 (+)-(3S,4R)-cis-3,4-Dihydroxy-3,4-dihydrofluorene
C07722 3,4-Dihydroxy-3,4-dihydro-9-fluorenone
C07725 2-Hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene)but-2-enoic acid
C11425 2-Hydroxy-2H-benzo[h]chromene-2-carboxylate
C11426 cis-4-(1'-Hydroxynaphth-2'-yl)-2-oxobut-3-enoate
C11427 1-Hydroxy-2-naphthaldehyde
C11428 trans-9(S),10(S)-Dihydrodiolphenanthrene
C11429 Phenanthrene-9,10-oxide
C16149 (3Z)-4-(2-Carboxyphenyl)-2-oxobut-3-enoate
C16203 Anthracene-cis-1,2-dihydrodiol
C16205 Anthracene-9,10-dihydrodiol
C16206 9,10-Dihydroxyanthracene
C16208 1-Methoxy-2-hydroxyanthracene
C16209 3-(2-Carboxyvinyl)naphthalene-2-carboxylic acid
C16210 4-(3-Hydroxy-2-naphthyl)-2-oxobut-3-enoic acid
C16213 2,3-Dihydroxynaphthalene
C16214 3-[6-(Carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate
C16215 1,2-Dihydrophthalic acid
C16262 1-Hydro-1,1a-dihydroxy-9-fluorenone
C16263 2,3-Dihydroxy-2'-carboxybiphenyl
C16264 2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate
C18249 cis-4,5-Dihydroxy-4,5-dihydropyrene
C18252 Phenanthrene-4,5-dicarboxylate
C18253 Phenanthrene-4-carboxylate
C18255 trans-4,5-Dihydroxy-4,5-dihydropyrene
C18256 cis-3,4-Phenanthrenedihydrodiol-4-carboxylate
C18261 1-Hydroxy-6-methoxypyrene
C18262 1-Methoxypyrene-6,7-oxide
C18265 1-Hydroxypyrene-6,7-oxide
C18266 1-Hydroxypyrene-7,8-oxide
C18270 Benzo[a]pyrene-cis-4,5-dihydrodiol
C18271 cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate
C18272 cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate
C18273 7,8-Dihydropyrene-8-carboxylate
C18274 7,8-Dihydropyrene-7-carboxylate
C18275 Benzo[a]pyrene-cis-7,8-dihydrodiol
C18276 Benzo[a]pyrene-cis-9,10-dihydrodiol
C18277 4,5-Chrysenedicarboxylate
C18278 9,10-Dihydroxybenzo[a]pyrene
C18279 4,5-Dihydroxybenzo[a]pyrene
C18280 11,12-Dihydroxybenzo[a]pyrene
C18281 10-Oxabenzo[def]chrysen-9-one
C18284 Benzo[a]pyrene-cis-11,12-dihydrodiol
C18285 Benzo[a]pyrene-trans-11,12-dihydrodiol
C18286 Benzo[a]pyrene-11,12-epoxide
C18314 Phthalate 3,4-cis-dihydrodiol
C21450 4-(2-Hydroxyethoxycarbonyl)benzoate
C21451 Poly(ethylene terephthalate)
Reference Authors Wattiau P, Bastiaens L, van Herwijnen R, Daal L, Parsons JR, Renard ME, Springael D, Cornelis GR.
Title Fluorene degradation by Sphingomonas sp. LB126 proceeds through protocatechuic acid: a genetic analysis.
Journal Reference Authors Story SP, Kline EL, Hughes TA, Riley MB, Hayasaka SS.
Title Degradation of aromatic hydrocarbons by Sphingomonas paucimobilis strain EPA505.
Journal Reference Authors Habe H, Chung JS, Kato H, Ayabe Y, Kasuga K, Yoshida T, Nojiri H, Yamane H, Omori T.
Title Characterization of the upper pathway genes for fluorene metabolism in Terrabacter sp. strain DBF63.
Journal Reference Authors Nojiri H, Habe H, Omori T.
Title Bacterial degradation of aromatic compounds via angular dioxygenation.
Journal Reference Authors Pagnout C, Frache G, Poupin P, Maunit B, Muller JF, Ferard JF.
Title Isolation and characterization of a gene cluster involved in PAH degradation in Mycobacterium sp. strain SNP11: expression in Mycobacterium smegmatis mc(2)155.
Journal Reference Authors Dean-Ross D, Moody JD, Freeman JP, Doerge DR, Cerniglia CE.
Title Metabolism of anthracene by a Rhodococcus species.
Journal Reference Authors Moody JD, Freeman JP, Doerge DR, Cerniglia CE.
Title Degradation of phenanthrene and anthracene by cell suspensions of Mycobacterium sp. strain PYR-1.
Journal Reference Authors van Herwijnen R, Springael D, Slot P, Govers HA, Parsons JR.
Title Degradation of anthracene by Mycobacterium sp. strain LB501T proceeds via a novel pathway, through o-phthalic acid.
Journal Reference Authors Haritash AK, Kaushik CP
Title Biodegradation aspects of polycyclic aromatic hydrocarbons (PAHs): a review.
Journal Reference Authors Liang Y, Gardner DR, Miller CD, Chen D, Anderson AJ, Weimer BC, Sims RC
Title Study of biochemical pathways and enzymes involved in pyrene degradation by Mycobacterium sp. strain KMS.
Journal Reference Authors da Silva M, Esposito E, Moody JD, Canhos VP, Cerniglia CE
Title Metabolism of aromatic hydrocarbons by the filamentous fungus Cyclothyrium sp.
Journal Reference Authors Kim SJ, Kweon O, Jones RC, Freeman JP, Edmondson RD, Cerniglia CE
Title Complete and integrated pyrene degradation pathway in Mycobacterium vanbaalenii PYR-1 based on systems biology.
Journal Reference Authors Wunder T, Marr J, Kremer S, Sterner O, Anke H
Title 1-Methoxypyrene and 1,6-dimethoxypyrene: two novel metabolites in fungal metabolism of polycyclic aromatic hydrocarbons.
Journal Reference Authors Schneider J, Grosser R, Jayasimhulu K, Xue W, Warshawsky D
Title Degradation of pyrene, benz[a]anthracene, and benzo[a]pyrene by Mycobacterium sp. strain RJGII-135, isolated from a former coal gasification site.
Journal Reference Authors Moody JD, Freeman JP, Fu PP, Cerniglia CE
Title Degradation of benzo[a]pyrene by Mycobacterium vanbaalenii PYR-1.
Journal Reference Authors Eaton RW
Title Plasmid-encoded phthalate catabolic pathway in Arthrobacter keyseri 12B.
Journal Reference Authors Yoshida S, Hiraga K, Takehana T, Taniguchi I, Yamaji H, Maeda Y, Toyohara K, Miyamoto K, Kimura Y, Oda K
Title A bacterium that degrades and assimilates poly(ethylene terephthalate).
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