Rattus norvegicus (rat): 57027
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Entry
57027 CDS
T01003
Symbol
Adam17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 precursor
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04148
Efferocytosis
rno04330
Notch signaling pathway
rno04668
TNF signaling pathway
rno05010
Alzheimer disease
rno05171
Coronavirus disease
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
57027 (Adam17)
04668 TNF signaling pathway
57027 (Adam17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
57027 (Adam17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease
57027 (Adam17)
09164 Neurodegenerative disease
05010 Alzheimer disease
57027 (Adam17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
rno01002
]
57027 (Adam17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
rno04090
]
57027 (Adam17)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
57027 (Adam17)
Peptidases and inhibitors [BR:
rno01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
57027 (Adam17)
CD molecules [BR:
rno04090
]
Proteins
57027 (Adam17)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Reprolysin_2
Reprolysin_5
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
57027
NCBI-ProteinID:
NP_064702
RGD:
620404
Ensembl:
ENSRNOG00000060694
UniProt:
Q9Z1K9
G3V711
LinkDB
All DBs
Position
6:complement(46601583..46663690)
Genome browser
AA seq
827 aa
AA seq
DB search
MRQRLLFLTTLVPFVLAPRPPEEPGSGSHPRLEKLDSLLSDYDILSLSNIQQHSIRKRDL
QSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGKEESEYSVKWQDFFSGHVV
GEPDSRVLAHIGDDDVTVRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKDFSRLQS
PKVCGYLNADSEELLPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRILKSPQEVKPGERHFNM
AKSFPNEEKDAWDVKMLLEQFSLDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYNPGVKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACADTDNSC
KVCCRNLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLS
INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMD
SASVRIIKPFPAPQTPGRLQALQPAAMMPPVSAAPKLDHQRMDTIQEDPSTDSHVDDDGF
EKDPFPNSSAAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC
NT seq
2484 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagcgtctcctcttcctgaccactttggtgcctttcgtcctggcaccccgacct
ccggaggaaccaggctctggctcccacccgcgacttgagaagcttgattctttgctctca
gactacgatatcctctctttatctaatatccagcagcactccataaggaaaagggatcta
cagtctgcgacacacttagaaacactactaactttttcagctttgaaaaggcattttaaa
ttatacttgacatcaagtacagaacgcttttcacagaacttgcgagtcgtggtggtggat
gggaaagaggaaagcgagtacagtgtgaagtggcaggacttcttcagcggacatgtggtt
ggtgagcctgactctagggttctagcgcacataggagatgatgatgtcacagtaagaatc
aacacagatggggcagaatataacatagagccactttggaggtttgttaatgatactaaa
gataaaaggatgctggtgtataagtctgaagatatcaaggatttttcacgtttgcagtct
ccaaaagtatgtggttatttaaatgcagatagtgaagagttgcttccaaaagggctcata
gacagagagccatctgaagagtttgtccgtcgagtgaagaggcgagctgaacctaaccca
ttgaagaatacttgtaaattactggtggtggcagatcatcgattttataagtacatgggc
cgaggagaagagagcactactacaaattacttaatagagttaattgaccgagttgatgac
atataccggaacacctcgtgggacaatgcaggatttaaaggttatggagtacagatagaa
cagattcgaattctcaagtctccacaagaggtaaaacctggtgaaagacacttcaatatg
gcaaaaagttttccaaatgaagaaaaggatgcttgggatgtgaagatgctgctggagcaa
tttagccttgatatagctgaagaggcctctaaagtctgcctggctcatcttttcacctac
caagattttgatatgggaactcttggattagcttacgttggttctcccagagcaaacagt
catggaggggtttgtccaaaagcttattacaacccaggtgtgaagaagaacatctatttg
aatagtggtctgacaagtacaaaaaattatggtaaaaccatccttacaaaggaggctgac
ctggttacaactcatgaattgggacacaattttggagcagaacatgatcctgatgggctg
gcagagtgtgccccaaatgaggaccaaggaggaaagtatgttatgtaccccatagctgtg
agtggtgaccatgagaataataagatgttttcaaactgcagtaaacagtccatctacaag
accatagaaagcaaggctcaagagtgcttccaggagcgcagcaacaaggtgtgcggcaac
tccagggtggacgaaggagaagagtgtgacccgggcatcatgtacctgaacaacgacacc
tgctgcaatagtgactgcacactgaagccaggtgtgcagtgcagtgataggaatagtcct
tgctgtaaaaattgtcagtttgagacggcccagaagaagtgccaggaggctatcaatgct
acttgcaaaggagtgtcttactgcacagggaatagcagtgagtgccccccaccaggagat
gctgaagatgacactgtgtgcttggacctgggcaagtgcaaggctgggaaatgcatccct
ttctgcaagagggagcaggagctggagtcctgcgcatgtgctgacaccgacaactcgtgc
aaggtatgctgcaggaacctttctggcccatgtgtgccttacgtcgatgcagagcaaaag
aacttatttttgaggaaagggaagccctgtacagtagggttttgtgacatgaatggcaaa
tgtgagaaacgggtacaggacgtaattgagcggttttgggatttcattgaccagctgagc
atcaacacttttgggaagtttctggcagacaacatcgttgggtctgttctggttttctcc
ttgatattttggattcctttcagcattcttgtccactgtgtggataagaaactggacaag
cagtatgagtccctgtctctgtttcatcacagtaacattgagatgttgagcagcatggac
tcagcatctgttcgcattatcaagccgttccctgcaccccagactccaggtcgtctgcag
gccctgcagccggctgcaatgatgccgccagtgtctgcggctccaaaactggatcaccag
aggatggacaccatccaggaagaccccagcacagattcacatgtggatgatgatggcttt
gagaaggaccccttccccaacagcagtgcagccgccaagtcctttgaggacctcacagac
cacccagtcaccaggagtgagaaggccgcctccttcaagctgcagcgtcagagccgagtt
gacagcaaagagacagagtgttag
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