Streptomyces albireticuli: SMD11_0676
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Entry
SMD11_0676 CDS
T05230
Symbol
actI2
Name
(GenBank) Polyketide chain length factor WhiE-CLF protein
KO
K05552
minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
salj
Streptomyces albireticuli
Pathway
salj00253
Tetracycline biosynthesis
salj01056
Biosynthesis of type II polyketide backbone
salj01100
Metabolic pathways
salj01110
Biosynthesis of secondary metabolites
Module
salj_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
salj00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
SMD11_0676 (actI2)
00253 Tetracycline biosynthesis
SMD11_0676 (actI2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
salj01004
]
SMD11_0676 (actI2)
01008 Polyketide biosynthesis proteins [BR:
salj01008
]
SMD11_0676 (actI2)
Enzymes [BR:
salj01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
SMD11_0676 (actI2)
2.3.1.260 tetracycline polyketide synthase
SMD11_0676 (actI2)
Lipid biosynthesis proteins [BR:
salj01004
]
Polyketide synthase
Component type
SMD11_0676 (actI2)
Polyketide biosynthesis proteins [BR:
salj01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
SMD11_0676 (actI2)
Nonaketide PKS
SMD11_0676 (actI2)
Decaketide PKS
SMD11_0676 (actI2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Thiolase_C_1
Motif
Other DBs
NCBI-ProteinID:
ARZ66342
LinkDB
All DBs
Position
759603..760916
Genome browser
AA seq
437 aa
AA seq
DB search
MSAVGAAAVARQPGPGASPHPGTRPVYVTGIGVAAPNGLGLERYWEAVLAGRSGVVPITR
FDTSRYPARLAGQIEDFDASAHLPSRLLPQTDVSTRLALTAADWAIADAGVDPSSTTDYD
MGVVTSNGCGGFEFTHREFKKLWSVGPQAVSVYESFAWFYAVNTGQISIRNGMRGPSSAL
VAEQAGGLDALGHARRTVHRGTPLVVTGGVDSAFDPWGWVSHLSSGRISHATDPERAYLP
FDAAACGYVPGEGGAILVVEDPVAARARGAGRVYGEIAGYASTFDPAPEGVRGELAAPPG
RPPGLRRAAEQALAQAGLTPQDVDVVFADAAGVRDLDRAEATAIRELFGAHRVPVTAPKA
LTGRLYAGGGPLDVATALLTIRDGVIPASGAVVDVPADYGIDLVTKGPREARVACALVLA
RGRWGFNSAVVVREATL
NT seq
1314 nt
NT seq
+upstream
nt +downstream
nt
atgagtgccgtcggagcggcggccgtcgcgcggcagcccggccccggcgcgagcccgcac
ccgggcacccgcccggtgtacgtgaccggcatcggcgtcgccgcgcccaacggcctcggc
ctggagcgctactgggaggcggtcctcgcgggccgctcgggcgtcgtaccgatcacccgc
ttcgacacgtcccgctatccggcccggctggcgggtcagatcgaggacttcgacgcgtcc
gcgcacctgccgagccggctccttccgcagaccgacgtctcgacccggctcgcgctgacc
gccgcggactgggcgatcgccgacgcgggcgtggatccgtcgagcaccacggactacgac
atgggcgtggtgacctccaacgggtgcggcggcttcgagttcacccaccgggagttcaag
aagctgtggagcgtcggcccccaggcggtcagcgtgtacgagtccttcgcctggttctac
gcggtcaacaccggtcagatctcgatccgcaacggtatgcgcggacccagcagcgccctg
gtggccgagcaggccggcggcctcgacgccctcggacacgcccggcgcaccgtccaccgc
ggcactcccctggtggtcaccggaggcgtggactccgcgttcgacccgtgggggtgggtc
tcccacctgtccagcgggcggatcagccacgccaccgacccggagcgcgcctacctgccg
ttcgacgcggcggcctgcggctatgtgccgggcgagggcggggcgatcctggtggtcgag
gaccccgtggcggcccgggcgcgcggggcgggccgggtgtacggggagatcgccgggtac
gcctcgaccttcgaccccgccccggagggcgtccggggggaactcgccgcacctcccggg
cggccaccggggctgcgccgggcggccgagcaggccctggcccaggccgggctgacgccc
caggacgtggacgtggtgttcgcggacgcggccggtgtccgcgacctggaccgtgccgag
gccacggcgatccgggagcttttcggggcacaccgggtgccggtgaccgcgcccaaggcg
ctcaccgggaggctctacgcgggcggcggtccgctggacgtcgccaccgcgctcctgacc
atccgggacggtgtgatcccggcttccggggccgtcgtcgacgtcccggccgattacggg
atcgacctggtgaccaagggcccgcgggaggcccgcgtcgcctgcgccctggtcctcgcc
cgcggccgatgggggttcaactcggccgtggtggtacgcgaggcaaccctctga
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