KEGG   Sorghum bicolor (sorghum): 8068714
Entry
8068714           CDS       T01086                                 
Name
(RefSeq) bifunctional dihydrofolate reductase-thymidylate synthase isoform X2
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
sbi  Sorghum bicolor (sorghum)
Pathway
sbi00240  Pyrimidine metabolism
sbi00670  One carbon pool by folate
sbi00790  Folate biosynthesis
sbi01100  Metabolic pathways
sbi01232  Nucleotide metabolism
sbi01240  Biosynthesis of cofactors
Module
sbi_M00126  Tetrahydrofolate biosynthesis, GTP => THF
sbi_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:sbi00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    8068714
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    8068714
   00670 One carbon pool by folate
    8068714
Enzymes [BR:sbi01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     8068714
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     8068714
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-GeneID: 8068714
NCBI-ProteinID: XP_002449495
UniProt: C5Y2E9
LinkDB
Position
5:50599462..50612412
AA seq 521 aa
MAAAPANGDSQSGPQRNYQVVVAATRDMGIGKDGVLPWKLLGDLKFFKELTLTTSDPAKK
NAVIMGRKTWESIPVKSRPLPGRLNVILTRSGSFDFATVENVVICGSMNSALELLASTPY
CLSIEKVFVVGGGQVLREYLNGPACEAIHLTDIQSSIECDTFIPPVDFSVFQPWYSSFPV
VESNIRHSFVTFVRVRKSVAETHESNGKESTEVDTKNDKFEIENFSFLPEMVYDRHEEYQ
YLNLVEDIIRSGAQKNDRTGTGTMSKFGCQMRFNLRKNFPLLTTKRVFWRGVVEELLWFI
SGSTNAKVLQEKGIHIWDGNASREYLDSVGLAHREEGDLGPVYGFQWRHFGAEYTDMHAD
YTGKGFDQLMDVIDKIKNNPDDRRIIMSAWNPSDLKKMALPPCHMFAQFYVENGELSCQM
YQRSADMGLGVPFNIASYSLLTYMIAQVCDLSPGDFVHVIGDAHVYRTHVRALEEQIQKM
PKPFPILKINPSKKDIDSFMASDFKLVGYDPHQKIEMKMAV
NT seq 1566 nt   +upstreamnt  +downstreamnt
atggctgcagctccggccaatggtgattcacagagtggtcctcagaggaactaccaggtt
gttgttgctgccactcgtgacatgggcattgggaaggatggggttctgccatggaagctt
cttggtgatcttaaattcttcaaagagcttacactaactacatctgatcctgccaagaag
aatgcagttataatgggaaggaaaacatgggagagcattcctgttaagtcaaggccattg
cctggtcgtttgaatgtcatacttactcgatctggtagctttgattttgcaacagtagag
aatgttgttatatgtggaagtatgaattctgccttagaactgctagcatcaactccatac
tgcttatcaattgagaaagtttttgttgtaggaggtgggcaggtactgagagaatatctt
aatggacctgcttgtgaggctatccatctaactgacattcagtcgagcattgagtgtgac
actttcatccctccagttgacttctcagtgttccagccatggtattcatctttcccagtg
gtagagagcaacattaggcattcttttgtgacttttgttcgtgttagaaagtcagtggca
gaaactcatgagtcaaatggcaaggaatcaactgaggttgataccaagaatgacaaattt
gaaatagagaatttctcttttctccccgagatggtatatgaccgccatgaggagtatcaa
tatctcaatcttgttgaagatattataagatctggtgctcagaaaaatgacaggacagga
actggaacaatgtcaaaatttggatgtcagatgcggttcaacttaaggaaaaattttcct
ctgctgacaacaaagagggtattttggcgtggtgttgtcgaagaactcctttggttcatc
agtggctcaacaaatgcaaaggttttgcaagagaagggtattcacatctgggatggcaat
gcttcaagagagtatcttgacagtgttggcttggcacacagggaggaaggtgatctaggt
ccagtttatggatttcaatggcgtcactttggtgctgaatacactgacatgcatgctgac
tatactggaaaaggttttgatcagctaatggatgtgattgacaagatcaagaataatcct
gatgaccgccgaataattatgtctgcgtggaatccttcagatctcaagaagatggctctt
cctccttgccacatgtttgcacaattttatgttgaaaatggggagctatcctgccagatg
tatcaacgctctgcagacatggggcttggtgttccattcaacatcgcatcatattctctt
ctgacatacatgatcgctcaagtttgtgatctttctcctggagattttgtccatgttata
ggggatgctcatgtctatagaactcatgttcgagctctggaggagcaaattcagaagatg
cctaaaccatttccaattttgaagataaatccttcaaaaaaggatatagattctttcatg
gcatcagacttcaagctggttggctatgatcctcaccagaagatagagatgaaaatggca
gtgtaa

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