Streptomyces coelicolor: SCO5088
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Entry
SCO5088 CDS
T00085
Symbol
SCBAC28G1.14
Name
(GenBank) actinorhodin polyketide beta-ketoacyl synthase beta subunit
KO
K05552
minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
sco
Streptomyces coelicolor
Pathway
sco00253
Tetracycline biosynthesis
sco01056
Biosynthesis of type II polyketide backbone
sco01100
Metabolic pathways
sco01110
Biosynthesis of secondary metabolites
Module
sco_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
sco00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
SCO5088 (SCBAC28G1.14)
00253 Tetracycline biosynthesis
SCO5088 (SCBAC28G1.14)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
sco01004
]
SCO5088 (SCBAC28G1.14)
01008 Polyketide biosynthesis proteins [BR:
sco01008
]
SCO5088 (SCBAC28G1.14)
Enzymes [BR:
sco01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
SCO5088 (SCBAC28G1.14)
2.3.1.260 tetracycline polyketide synthase
SCO5088 (SCBAC28G1.14)
Lipid biosynthesis proteins [BR:
sco01004
]
Polyketide synthase
Component type
SCO5088 (SCBAC28G1.14)
Polyketide biosynthesis proteins [BR:
sco01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
SCO5088 (SCBAC28G1.14)
Nonaketide PKS
SCO5088 (SCBAC28G1.14)
Decaketide PKS
SCO5088 (SCBAC28G1.14)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Motif
Other DBs
NCBI-ProteinID:
CAC44201
Kitasato:
SCO5088
UniProt:
Q02062
Structure
PDB
PDBj
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All DBs
Position
5531201..5532424
Genome browser
AA seq
407 aa
AA seq
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MSVLITGVGVVAPNGLGLAPYWSAVLDGRHGLGPVTRFDVSRYPATLAGQIDDFHAPDHI
PGRLLPQTDPSTRLALTAADWALQDAKADPESLTDYDMGVVTANACGGFDFTHREFRKLW
SEGPKSVSVYESFAWFYAVNTGQISIRHGMRGPSSALVAEQAGGLDALGHARRTIRRGTP
LVVSGGVDSALDPWGWVSQIASGRISTATDPDRAYLPFDERAAGYVPGEGGAILVLEDSA
AAEARGRHDAYGELAGCASTFDPAPGSGRPAGLERAIRLALNDAGTGPEDVDVVFADGAG
VPELDAAEARAIGRVFGREGVPVTVPKTTTGRLYSGGGPLDVVTALMSLREGVIAPTAGV
TSVPREYGIDLVLGEPRSTAPRTALVLARGRWGFNSAAVLRRFAPTP
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
atgagcgtcctcatcaccggagtcggcgtcgtcgcacccaacggcctcggcctggcgccg
tactggtcggcggtgctggacggccgccacggcctcggcccggtcacccgcttcgacgtg
agccggtacccggcgaccctcgccggccagatcgacgacttccacgcgccggaccacatc
ccgggccggttgctgccgcagacggacccctccacacggctcgcgctgaccgccgcggac
tgggccctccaggacgcgaaggcggacccggagtcgctgaccgactacgacatgggcgtg
gtgaccgccaacgcctgcggtgggttcgacttcacccaccgggagttccgcaagctgtgg
tccgagggccccaagtcggtcagcgtgtacgagtccttcgcctggttctacgcggtgaac
accggccagatctccatccggcacggtatgcgcggtccgagcagtgccctggtcgccgag
caggccgggggcctggacgccctgggccacgcccgccgtacgatccgccgcggcacgccg
ctggtggtctccggcggggtggactcggcactcgacccgtggggctgggtctcgcagatc
gccagtggccggatcagcacggccaccgatccggaccgggcgtatctgcccttcgacgag
cgggcggccggctacgttccgggcgagggcggggccatcctcgtcctggaggacagcgcc
gcggccgaggcccgcggccggcacgacgcgtacggcgaactcgccggctgcgcctccacc
ttcgaccccgcccccggatccggacggcccgcgggcctggaacgcgcgatccggctggcg
ctgaacgacgccgggaccggtcccgaggacgtcgacgtcgtgttcgccgacggcgcgggc
gtgcccgagctggacgccgccgaggcccgggcgatcggccgggtgttcggccgcgaaggg
gtgcccgtcaccgtccccaagacgacgacgggccgcctctactccggcggcggcccgctc
gacgtggtcaccgccctgatgtccctgcgcgaaggggtgatcgcgccgaccgcgggcgtg
acgtccgtaccccgggagtacggcatcgacctggtgctcggcgaaccccgcagcacggcc
ccgcgcaccgcactggtcctggccaggggccgctggggcttcaactcggcggcggtcctg
cgccgtttcgcaccgaccccgtaa
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