Serratia sp. FS14: L085_03855
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Entry
L085_03855 CDS
T03313
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase II/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
serf
Serratia sp. FS14
Pathway
serf00260
Glycine, serine and threonine metabolism
serf00261
Monobactam biosynthesis
serf00270
Cysteine and methionine metabolism
serf00300
Lysine biosynthesis
serf01100
Metabolic pathways
serf01110
Biosynthesis of secondary metabolites
serf01120
Microbial metabolism in diverse environments
serf01230
Biosynthesis of amino acids
Module
serf_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
serf_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
serf_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
serf00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
L085_03855 (metL)
00270 Cysteine and methionine metabolism
L085_03855 (metL)
00300 Lysine biosynthesis
L085_03855 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
L085_03855 (metL)
Enzymes [BR:
serf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
L085_03855 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
L085_03855 (metL)
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Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
AIA46227
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Position
complement(845129..847564)
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AA seq
811 aa
AA seq
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MNAIAVAGPVSGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPGDMMVVSAAGSTTNQLIN
WLKLSQSDRLSAHQVQQTLRRYHSDLISGLLPPESAEPLIAEFIQDLERLAALLDGNVDE
VCYAEVVGHGEIWSARLMAAVLNHLDMQAAWLDARDFLRAERAAQPQVDEGRSYPLLQQL
MAQHPGKRLVVTGFISRNDAGETVLLGRNGSDYSATQVGALAGAARVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHTRTLQPVSGSDIDLQLRCSYQPEQGSTRIE
RVLASGTGAKIVTSHDDVCLIELHVAAQHDFKLAQKELDLVLKRAQIKPLAVGIHPDRNL
VQLCYTSEVVNSALATLQAAALPGELRLREGLALVAMVGAGVCKNPLHSHRFYQQLKDQP
VEFIWQAEDGISLVAVLRQGPTALLIQGLHQSLFRAEKRIGLVLFGKGNIGSRWLELFAR
EQTNISARSGFEFILAGVVDSRRSLLNYDGLDASRALAFFEDEAQELDEESLFLWMRAHP
FDDLVVLDVTASEELAGQYLDFASYGFHVISANKLAGASCSDSYRQIRDAFAKTGRHWLY
NATVGAGLPVNHTVRDLRDSGDSILAISGIFSGTLSWLFLQYDGTVPFTELVDQAWQQGL
TEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGCELGSVDQFFENGEALN
QQMQQRFEAASEMGLVLRHVARFDANGKARVGVEAVRPEHPLASLLPCDNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLAQLL
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atgaatgcaattgctgtagcagggccggtgagcgggcgtcaactgcacaagtttggcggc
agcagtctggcggatgtgaagtgttatctgcgtgtggccgggattatggcggaatacagc
cagccgggcgacatgatggtggtatcggccgccggcagtaccaccaaccagttgatcaac
tggctgaagctcagccagagcgatcgcctgtctgcgcaccaggtgcagcagacgttgcgt
cgttatcacagcgatcttatcagcggcctgttgccgccggaaagcgcagagccgctgatc
gccgagttcattcaggatctggaacgtctggcggcgctgctggacggcaacgtcgacgag
gtgtgctacgccgaagtggtcgggcacggcgagatttggtcggcgcgcctgatggcggcg
gtgctcaaccacctggacatgcaggcggcctggctggatgcgcgtgacttcctgcgcgcc
gagcgcgccgcgcagccgcaggtggatgaaggccgttcttacccgctgttgcaacaattg
atggcccaacacccgggtaaacgcctggtggtgaccgggttcatttcgcgcaacgacgcc
ggggaaaccgtgctgttggggcgtaacggcagcgactactccgccactcaggtcggcgcg
ctggccggcgctgcgcgcgtcaccatctggagcgacgtggccggggtttacagcgccgat
ccgcgcaaggtgaaagatgcctgcctgctgccgctgctgcgtctggacgaagccagcgag
ctggcgcgtctggctgcgccggtgttgcacacccgcaccctgcagccggtctccggcagc
gatatcgatcttcagctgcgctgcagctatcagccggagcagggctcgacgcgcattgag
cgcgtattggcgtccggcaccggcgccaagattgtcaccagccacgacgatgtgtgcctg
attgaactgcacgttgccgctcagcatgacttcaaactggcgcagaaagagttggatctg
gtgctcaagcgcgcgcagatcaaaccgctggcggtgggcatccaccctgaccgcaacctg
gtgcagctgtgctacacctccgaggtggtcaacagcgcgctggcgacgctgcaggccgcg
gcgctgccaggcgagctgcgcctgcgcgaagggttggcgctggtggcgatggtcggcgcc
ggggtgtgcaagaacccgctgcacagccaccgtttctatcaacagttgaaagatcagccg
gtcgagtttatctggcaggcggaagatggcatcagcctggtggcggtattgcgccagggg
ccgaccgcgctgctgatccaggggctgcaccaaagcctgttccgcgccgagaagcgcatc
ggtctggtgctgttcggcaagggcaatatcggctcgcgctggctggagctgttcgcccgt
gagcagaccaatatctccgcgcgcagcggcttcgaatttatcctggcgggggtggtggac
agccgccgcagcctgctgaactatgacgggctggacgccagccgcgcgctggcattcttt
gaggatgaggcgcaggagctggatgaagaatcgctgttcctgtggatgcgcgcgcacccg
ttcgacgatctggtggtgctcgacgtgaccgccagcgaagagctggccgggcagtatctg
gacttcgccagctacggtttccacgtgatcagcgccaacaagttggcgggggcctcgtgc
agcgacagctatcgccaaattcgcgacgccttcgccaaaaccggccgccactggctgtac
aacgccaccgtcggcgccggcctgccggtcaaccacacggtgcgcgatctgcgcgacagc
ggcgacagcattttggcgatcagcggcatcttctccggcacgctctcctggctgttcctg
cagtatgacggcacggtgccgtttaccgagctggtggatcaggcctggcagcaggggctg
accgaaccggatccgcgggtcgatctctccggccaggacgtgatgcgcaagctggtgatc
ctggcgcgcgaagcgggttacgacatcgagccgaatcaggtgcgggtcgagtcgctggtg
ccggcgggctgcgagctgggctccgtcgatcagttcttcgagaacggtgaggcgctgaac
cagcagatgcagcagcgctttgaggccgccagcgaaatgggcctggtgttgcgccacgtg
gcgcgtttcgacgccaacggcaaggcgcgggtcggcgtggaggcggtgcgccctgagcat
cctctggcctcgctgctgccgtgcgacaacgtgttcgccatcgaaagccgctggtatcgc
gataatccgctggtgatccgcgggccgggcgccggccgcgacgtcaccgccggcgcgatc
cagtcagaccttaaccgattggcgcagctgctttaa
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