Suncus etruscus (white-toothed pygmy shrew): 126019057
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Entry
126019057 CDS
T09902
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
setr
Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr00350
Tyrosine metabolism
setr00790
Folate biosynthesis
setr01100
Metabolic pathways
setr04728
Dopaminergic synapse
setr04917
Prolactin signaling pathway
setr05012
Parkinson disease
setr05030
Cocaine addiction
setr05031
Amphetamine addiction
setr05034
Alcoholism
Module
setr_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
setr00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
126019057 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
126019057 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
126019057 (TH)
09156 Nervous system
04728 Dopaminergic synapse
126019057 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
126019057 (TH)
09165 Substance dependence
05030 Cocaine addiction
126019057 (TH)
05031 Amphetamine addiction
126019057 (TH)
05034 Alcoholism
126019057 (TH)
Enzymes [BR:
setr01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
126019057 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
ACT
LTP_2
Motif
Other DBs
NCBI-GeneID:
126019057
NCBI-ProteinID:
XP_049637168
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All DBs
Position
9:114656178..114662733
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AA seq
489 aa
AA seq
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MPTPGTGAPQAKGFRRAVSELDSKHAEAIMSPRFIGRRQSLIQDARKEREKAETEPGEHS
KVAPLQEKDGRARLALLFSLRGPKPSPLSRVLKAFETFEASIQHLESRRAPRPRAGDAGL
DFFVCCEVRGADLPALLSALRREADDVRGAGEQKALWFPRKVAELDQCHHLVTKFDPDLD
LDHPGFSDQAYRQRRKQIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYRTLKGLYATHAC
REHLQAFELLERCSGYAEDRIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVF
QCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLST
LYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEVRAFDPEEAAVQPYQDQTYQ
SVYFVSESFSDAKDKLRSYAARIQRPFSVRFDPYTLSIDVLDSPRAIRGALGGVQDEMHI
LAGALSAIS
NT seq
1470 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccctggcaccggcgccccccaggccaagggcttccgcagggccgtctccgag
ctggactcgaaacatgccgaggccatcatgtccccccgtttcatcggccgccgccagagc
ctcatccaggacgcgcgcaaggaacgggagaaggcagagacggagcccggggagcactcc
aaggtggccccactccaggagaaagacggccgggcccgcctggctctgctcttcagcctg
agggggcccaagcccagccccctgtcccgtgtcctcaaggcctttgagaccttcgaggcc
tccatccagcacctggagtcgcggcgggcgcccaggcctcgggcaggggacgcggggctg
gacttcttcgtgtgctgtgaggtgcggggagcggacctgcccgccttgctcagtgccctg
cgcagggaggcagatgacgtgcgcggtgccggggagcagaaggccctctggttcccgagg
aaggtggccgagttggaccagtgtcaccatctggtcaccaagttcgaccctgacctggac
ttggatcatccgggcttctcggaccaggcctaccgccagcgccgaaagcagatagcagag
attgccttccagtacaagcacggagaccccatcccacgcgtggagtacacggccgaggag
atcgctacctggaaggaggtgtaccgcaccctcaagggcctctacgccacgcacgcctgc
cgcgagcacctgcaagccttcgagctgctggagcgctgcagcggctacgccgaggaccgc
atcccgcagctggaggacgtgtcccgcttcctcaaggagcggaccggcttccagctgcgg
cccgtggccggcctgctgtcggcccgcgacttcctggccagcctggccttccgcgtgttc
cagtgcacccagtacatccgccacgcctcgtcgcccatgcactcgcccgagccggactgc
tgccacgagctcctggggcacgtgcccatgctggccgaccgcaccttcgcccagttctcc
caggacattggcttggcgtccctgggggcttcggatgaggaaatcgagaagctgtccacg
ctgtactggttcaccgtggagttcgggctgtgcaagcagaacggagaagtgaaggcctac
ggggccgggctgctgtcctcctacggggagctgctgcactgcctgtcggaggagcccgag
gtgcgggcgttcgacccggaggaggcggccgtgcagccgtaccaggatcagacctaccag
tcggtgtacttcgtgtccgagagcttcagcgatgccaaagacaagctcaggagctacgca
gcacgcatccagcgccccttctcggtgcggttcgacccctacacgctgagcattgacgtg
ctggacagtccccgggccatccggggtgcgctggggggcgtccaggatgagatgcacatc
ctggccggtgccctgagcgccatcagctag
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