Sorex fumeus (smoky shrew): 130023746 Help Entry 130023746         CDS       T10594                                  Symbol CASP3 Name (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum01524   Platinum drug resistance sfum04010   MAPK signaling pathway sfum04115   p53 signaling pathway sfum04148   Efferocytosis sfum04210   Apoptosis sfum04215   Apoptosis - multiple species sfum04623   Cytosolic DNA-sensing pathway sfum04650   Natural killer cell mediated cytotoxicity sfum04657   IL-17 signaling pathway sfum04668   TNF signaling pathway sfum04726   Serotonergic synapse sfum04932   Non-alcoholic fatty liver disease sfum04933   AGE-RAGE signaling pathway in diabetic complications sfum04936   Alcoholic liver disease sfum05010   Alzheimer disease sfum05012   Parkinson disease sfum05014   Amyotrophic lateral sclerosis sfum05016   Huntington disease sfum05020   Prion disease sfum05022   Pathways of neurodegeneration - multiple diseases sfum05132   Salmonella infection sfum05133   Pertussis sfum05134   Legionellosis sfum05145   Toxoplasmosis sfum05146   Amoebiasis sfum05152   Tuberculosis sfum05160   Hepatitis C sfum05161   Hepatitis B sfum05162   Measles sfum05163   Human cytomegalovirus infection sfum05164   Influenza A sfum05165   Human papillomavirus infection sfum05167   Kaposi sarcoma-associated herpesvirus infection sfum05168   Herpes simplex virus 1 infection sfum05169   Epstein-Barr virus infection sfum05170   Human immunodeficiency virus 1 infection sfum05200   Pathways in cancer sfum05203   Viral carcinogenesis sfum05205   Proteoglycans in cancer sfum05206   MicroRNAs in cancer sfum05210   Colorectal cancer sfum05222   Small cell lung cancer sfum05416   Viral myocarditis sfum05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:sfum00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     130023746 (CASP3)    04668 TNF signaling pathway     130023746 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     130023746 (CASP3)   09143 Cell growth and death    04210 Apoptosis     130023746 (CASP3)    04215 Apoptosis - multiple species     130023746 (CASP3)    04115 p53 signaling pathway     130023746 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     130023746 (CASP3)    04650 Natural killer cell mediated cytotoxicity     130023746 (CASP3)    04657 IL-17 signaling pathway     130023746 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     130023746 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     130023746 (CASP3)    05206 MicroRNAs in cancer     130023746 (CASP3)    05205 Proteoglycans in cancer     130023746 (CASP3)    05203 Viral carcinogenesis     130023746 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     130023746 (CASP3)    05222 Small cell lung cancer     130023746 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     130023746 (CASP3)    05161 Hepatitis B     130023746 (CASP3)    05160 Hepatitis C     130023746 (CASP3)    05164 Influenza A     130023746 (CASP3)    05162 Measles     130023746 (CASP3)    05168 Herpes simplex virus 1 infection     130023746 (CASP3)    05163 Human cytomegalovirus infection     130023746 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     130023746 (CASP3)    05169 Epstein-Barr virus infection     130023746 (CASP3)    05165 Human papillomavirus infection     130023746 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     130023746 (CASP3)    05133 Pertussis     130023746 (CASP3)    05134 Legionellosis     130023746 (CASP3)    05152 Tuberculosis     130023746 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     130023746 (CASP3)    05145 Toxoplasmosis     130023746 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     130023746 (CASP3)    05012 Parkinson disease     130023746 (CASP3)    05014 Amyotrophic lateral sclerosis     130023746 (CASP3)    05016 Huntington disease     130023746 (CASP3)    05020 Prion disease     130023746 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     130023746 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     130023746 (CASP3)    05416 Viral myocarditis     130023746 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     130023746 (CASP3)    04932 Non-alcoholic fatty liver disease     130023746 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     130023746 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     130023746 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:sfum01002]     130023746 (CASP3) Enzymes [BR:sfum01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      130023746 (CASP3) Peptidases and inhibitors [BR:sfum01002]  Cysteine peptidases   Family C14: caspase family    130023746 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 Erf4 Motif Other DBs NCBI-GeneID:  130023746 NCBI-ProteinID:  XP_055970312 LinkDB All DBs Position Unknown AA seq 276 aa AA seqDB search MENSEISVDAKSVKNSEEKIIHGSKSVDSGISLDNSYKMNYPEMGVCLIINNKNFKGEGM STRTGTDVDAARLKETFTNLKYEVRIKNDLTCEEIKKLLYSASLEDHSKRSSFICVFLSH GEEGTIFGTDKPIELKILAGFFKGDCCRSLTGKPKIFIIQACRGTELDCGIETDSGSEDD MTCQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCEILKRYADKLEFMHILTRVNQ KVATEFESYSLDRTFHAKKQIPCIMSMLTKELYFYH NT seq 831 nt NT seq  +upstreamnt  +downstreamnt atggagaactctgaaatctcagtagacgcaaaatccgtaaagaattcagaagaaaagatc atacatggcagcaagtcagtggactctggaatatcgttggacaatagttacaaaatgaat tatcctgaaatgggcgtgtgtttaataattaataataagaacttcaaaggcgaaggcatg tcgactcggaccggtacagatgtagatgcagcaagactcaaggaaacgtttactaacttg aaatacgaagtcaggatcaaaaatgatctgacctgtgaggaaattaagaaattgctgtac agtgcttctttagaagatcatagcaaaaggagcagttttatttgtgtgtttctaagccat ggtgaagaaggaaccatttttggaacagataaacctattgagctgaagatcttagcaggt ttcttcaaaggggattgttgcagaagtctaactggaaaacccaaaattttcattattcag gcctgccgaggtacagaactcgactgtggaatagagactgacagtggttctgaggatgac atgacgtgtcagaagataccagtggaagctgacttcttgtatgcgtattccacagcacct ggttactattcttggcgcaattcaaaggatggatcctggttcattcagtcactttgtgag atattgaagcggtacgctgacaaacttgagttcatgcacattcttactcgggtcaaccaa aaggtagcaacagaatttgagtcctattccttggacagaactttccacgcaaagaagcag attccatgtattatgtctatgctcacaaaagaactgtatttttatcactga

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