Sorex fumeus (smoky shrew): 130036036 Help Entry 130036036         CDS       T10594                                  Name (RefSeq) steroid 21-hydroxylase   KO K00513   steroid 21-monooxygenase [EC:1.14.14.16] Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum00140   Steroid hormone biosynthesis sfum01100   Metabolic pathways sfum04925   Aldosterone synthesis and secretion sfum04927   Cortisol synthesis and secretion sfum04934   Cushing syndrome Module sfum_M00109   C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone Brite KEGG Orthology (KO) [BR:sfum00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     130036036  09150 Organismal Systems   09152 Endocrine system    04925 Aldosterone synthesis and secretion     130036036    04927 Cortisol synthesis and secretion     130036036  09160 Human Diseases   09167 Endocrine and metabolic disease    04934 Cushing syndrome     130036036  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:sfum00199]     130036036 Enzymes [BR:sfum01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor     1.14.14.16  steroid 21-monooxygenase      130036036 Cytochrome P450 [BR:sfum00199]  Cytochrome P450, animal type   CYP21 family    130036036 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  p450 Motif Other DBs NCBI-GeneID:  130036036 NCBI-ProteinID:  XP_055983982 LinkDB All DBs Position Unknown AA seq 494 aa AA seqDB search MLLLGLFLLLLLLTSTRLLWSRGEPCKLHLPPLAPGLLHLLQPDHPIYLLGLAQKLGPIY RIRLGLQEVVVLNSKRTIEEAMVTKAVDFAGRPHAASYKLFFGDHQDISLGDYTQLWKAH KRLTRAALLHGMHNFLEPWMEKVTREFCEGLRAQAGTLVDIQKEFSLFTCRIITYLSFTE KEDTLVQVFHNNILDLLSAWEHWSTQILDIFPFFRFFPMPGHRKLKQALEKRGSLLEKQL QQHKESMVAGRPRDMTDYMLQEVSRQQGGRDLQLCERHVEMAVLDLIIGGLKTTSSTLSW VVLFLLHHPELQERLQEELDAQLEPGVSDCPFQYRDRGRLPLLNATISEVMRLRPVVPLG LPHRTMRPTSILGYDIPRDTVVIPNLQGALLDPTIWEQPRMFRPDRFLDPAGSTSVNSLV FGCGPRSCLGEPLARVEIFQVLVHLLQAFTLLPPEGALPSLEPEPYSVHNLKVQPFQVRL QQRRPGTSALGQRQ NT seq 1485 nt NT seq  +upstreamnt  +downstreamnt atgctgctcctgggactgtttctgctgctgctcctgctcaccagcacccgcctgctgtgg agccgcggggagccctgcaagctgcacctcccacctctggcccctggcctcttgcatctg ctgcagcctgaccaccccatctacctgctcggcctggctcagaagctcggacctatctac agaatccgcttggggctacaggaggtggtggtgctaaactcgaagaggaccattgaggag gccatggtcaccaaggcggtggactttgccggcagaccccatgcagcatcctacaagttg ttctttggggaccatcaagacatctctctgggagactatacccaactctggaaggcccac aaacggctcacccgcgctgccctgctgcacggcatgcacaacttcctggagccttggatg gagaaggtgacccgggagttctgtgagggcctgagagcccaggccggcaccctcgtggac atccagaaggaattctccctgttcacctgcaggatcatcacttacctcagcttcacagaa aaggaggacacgttagtccaggtttttcacaacaacatcctggacttactgtctgcctgg gaacactggtccacccagattttggacatctttccttttttcaggttcttccccatgccg ggccacaggaagctgaagcaggctctggagaagagaggcagcttgttagagaagcagctg cagcagcacaaggagagcatggtggcaggccggccgagggacatgactgactacatgctc caggaggtcagcaggcagcaggggggacgggacctgcagctctgtgaaaggcatgtggag atggcggtgctggacctgataatcggtggcttgaagaccacgtcgagcaccctctcctgg gttgtcctgttcttgcttcatcacccggagcttcaggagcgactgcaggaggagctggat gcacagctggagcctggagtctccgactgccccttccagtacagagaccgcgggcggctg cccttgctcaacgccaccatctcggaggtgatgcgcctgcggccggtggtacccctgggc ctgcctcaccgcaccatgcggcccaccagcatcctgggctacgacatcccccgggacacg gtggtcattcccaacttgcaaggcgccctgctggaccccacaatctgggagcagccgcgc atgttccggccagaccgcttcttggaccctgccggcagcaccagcgtcaactcactggtc tttggctgcgggccccgctcctgcctgggggagccgctggcccgcgtggagatcttccag gtgctggtgcatctgctgcaggccttcacgctgctgccgccagagggcgccctgccctcg ctggagcccgagccctactcggtgcacaacctcaaggtccagcctttccaggtgcggctg cagcagcgcaggccgggcacctccgcgctgggtcagcgccagtga

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