Sorex fumeus (smoky shrew): 130039856
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Entry
130039856 CDS
T10594
Symbol
TH
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum00350
Tyrosine metabolism
sfum00790
Folate biosynthesis
sfum01100
Metabolic pathways
sfum04728
Dopaminergic synapse
sfum04917
Prolactin signaling pathway
sfum05012
Parkinson disease
sfum05030
Cocaine addiction
sfum05031
Amphetamine addiction
sfum05034
Alcoholism
Module
sfum_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
130039856 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
130039856 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
130039856 (TH)
09156 Nervous system
04728 Dopaminergic synapse
130039856 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
130039856 (TH)
09165 Substance dependence
05030 Cocaine addiction
130039856 (TH)
05031 Amphetamine addiction
130039856 (TH)
05034 Alcoholism
130039856 (TH)
Enzymes [BR:
sfum01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
130039856 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
130039856
NCBI-ProteinID:
XP_055987773
LinkDB
All DBs
Position
Unknown
AA seq
491 aa
AA seq
DB search
MPTPGSGAPQAKGFRRAVSELDSKQAEAIMSPRFIGRRQSLIQDARKEREKAEAAAEPGE
SPEVAPLQERDGRASLALLFSLRGPKPAPLSRVLKAFETFEATIQHLESRRASRPRAGDA
GLDFFVRCEVRGADLPALLSSLRRVADDVRGAREQKALWFPRKVSELDRCHHLVTKFDPD
LDLDHPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEVATWKEVYRTLKGLYATH
ACREHLQAFELLERCSGYAEDRIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFR
VFQCTQYIRHSSSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKL
STLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEVRAFDPDEAAVQPYQDQT
YQSVYFVSESFSDAKDKLRSYAARIERPFSVRLDPYTLSIEVLDSPRAVRRSLGGVQDEL
HVLANALSAIS
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccggctccggcgcgccccaggccaagggcttccgcagggccgtctcggag
ctggactccaagcaggccgaggccatcatgtccccccgcttcatcggccgccggcagagc
ctcatccaggatgcccgcaaggagcgggagaaggcggaggcggcggctgagccgggcgag
tcccccgaggtggcgccccttcaggagcgggacggccgtgccagcctggccctgctcttc
agcctgcggggacccaagcccgccccgctgtcccgtgtcctcaaggccttcgagaccttc
gaggcgaccatccagcacctggagtcgcggcgggcgtccaggccgcgggcaggggacgcg
gggctggacttcttcgtgcgctgcgaggtccggggcgccgacctgccggcgctgctcagc
tccctgcgccgggtggcagacgacgtgcggggtgcccgggagcagaaggccctctggttc
ccgaggaaggtgtccgagctggaccggtgtcaccatctggtcaccaagttcgaccctgac
ctggacttggatcacccgggcttctcggaccaggcgtaccgccagcgccggaagctgatc
gccgagatcgccttccagtacaagcacggcgaccccatcccccgcgtggagtacacggcc
gaggaggtcgccacctggaaggaggtgtaccgcacgctcaaggggctctacgccacgcac
gcctgccgcgagcacctgcaggccttcgagctgctggagcgctgcagcggctacgccgag
gaccgcatcccgcagctggaggacgtgtcccgcttcctgaaggagaggacgggcttccag
ctgcggcccgtggccggcctgctgtccgcccgcgacttcctggccagcctggccttccgc
gtgttccagtgcacgcagtacatccggcactcctcgtcgcccatgcactcgcccgagccg
gactgctgccacgagctgctgggacacgtgcccatgctggccgaccggacctttgcgcag
ttctcccaggacatcggcctggcgtccctgggggcttcggacgaggagattgagaagctg
tccacgctctactggttcacggtggagttcgggctgtgcaagcagaacggcgaggtgaag
gcgtacggcgcggggctgctgtcgtcctacggggagctgctgcactgcctgtcggaggag
cccgaggtgcgcgccttcgacccggacgaggcggccgtgcagccctaccaggaccagacc
taccagtccgtgtacttcgtgtccgagagcttcagcgacgccaaggacaagctcaggagc
tacgcggcgcgcatcgagcgtcccttctccgtgcggctggacccgtacacgctgagcatc
gaggtgctggacagcccccgcgccgtgaggcgctccctggggggcgtccaggacgagctg
cacgtgctggccaacgccctgagcgccatcagctag
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