Streptomyces griseofuscus: HEP81_07942
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Entry
HEP81_07942 CDS
T07010
Name
(GenBank) ketosynthase chain-length factor
KO
K05552
minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
sgf
Streptomyces griseofuscus
Pathway
sgf00253
Tetracycline biosynthesis
sgf01056
Biosynthesis of type II polyketide backbone
sgf01100
Metabolic pathways
sgf01110
Biosynthesis of secondary metabolites
Module
sgf_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
sgf00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
HEP81_07942
00253 Tetracycline biosynthesis
HEP81_07942
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
sgf01004
]
HEP81_07942
01008 Polyketide biosynthesis proteins [BR:
sgf01008
]
HEP81_07942
Enzymes [BR:
sgf01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
HEP81_07942
2.3.1.260 tetracycline polyketide synthase
HEP81_07942
Lipid biosynthesis proteins [BR:
sgf01004
]
Polyketide synthase
Component type
HEP81_07942
Polyketide biosynthesis proteins [BR:
sgf01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
HEP81_07942
Nonaketide PKS
HEP81_07942
Decaketide PKS
HEP81_07942
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Nckap1
Motif
Other DBs
NCBI-ProteinID:
QNT98170
UniProt:
A0A7H1QCZ0
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All DBs
Position
pSGRIFU1:complement(125336..126586)
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AA seq
416 aa
AA seq
DB search
MTAAANGSTGLTRRRGAAVTGLGVVAPGGIGVRSWWEAMLRGETALGPVTRFDASGYPAT
LAGEVTGFADEDHVPAKLLPQTDRVTRLSLAAAAEALDDAGLEPRDLPDYAMGVVTANST
GGFEFGQRELQALWSKGRRHVGAYQSFAWFYAANSGQISIRHGLRGPSGVVVSEQAGGLD
AVAQARRRLRAGVRAVLTGGFDSAVCPWGWTALLAAGGMSTRDDAERAYLPFDADACGHV
AGEGGALLVLEEAGAARARGAAVLGTVEGCAATFDPAPGAGPPRLLAAARLALADARIGP
ADVDVVFADAAGERDADRAEARALAELFGPYGVAVTAPKSLTGRLGAGGSALDLAAALCA
LRDQVIPPTAGAVRVAGDCPVDLVRGAPRPARLRHALVLARGRGGFNAATVVRAAR
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgccgcggcgaacgggagcaccggcctgacgcggcggcgcggcgcggccgtcacc
gggctcggcgtcgtcgcccccggcggcatcggcgtgcggtcctggtgggaggcgatgctg
cgcggcgaaaccgccctcggccccgtcacccgcttcgacgcctccggctacccggcgacg
ctcgccggagaggtcacgggcttcgccgacgaggaccacgtaccggcgaagctgctgccg
cagaccgaccgggtgacgcggctgtcgctggccgccgccgccgaggcactggacgacgcg
ggcctggagccgcgggacctgcccgactacgccatgggtgtcgtcaccgccaactccacg
ggcggcttcgagttcggccagcgcgaactgcaggcgctgtggagcaagggccgccggcac
gtcggcgcctatcagtcgttcgcctggttctacgccgccaactcgggccagatctccatc
cggcacgggctgcgcgggccgagcggcgtcgtcgtcagcgagcaggcgggcggcctggac
gccgtcgcgcaggcccgccgccgactgcgcgccggtgtgcgcgcggtgctcaccggcggc
ttcgactccgccgtgtgcccgtggggctggaccgcgctgctggcggcgggcggcatgagc
acacgcgacgacgccgaacgcgcctacctgcccttcgacgccgacgcgtgcgggcatgtg
gccggagagggcggcgccctgctggtgctggaggaggccggcgcggcccgcgcccgcggc
gccgccgtgctcggcacggtcgagggctgcgccgccacgttcgacccggcgcccggcgcc
ggcccgccgcggctgctcgccgcggcccggctcgccctggccgacgcccggatcggcccc
gcggacgtggacgtggtcttcgccgacgcggccggcgagcgggacgccgaccgggccgag
gcccgagcgctcgccgagctgttcggcccgtacggggtggcggtcaccgcgcccaagtcg
ctgaccgggcggctgggcgcgggaggttccgcgctcgatctggcggccgccctgtgcgcc
ctgcgcgaccaggtgatcccgccgacggccggcgccgtccgggtggccggcgactgcccc
gtggacctggtgcgcggcgccccgcgcccggcccggctgcgccatgccctggtcctggcc
aggggccgcggcggcttcaacgcggcgacggtcgtccgcgcggcgcgctga
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