Streptomyces glaucescens: SGLAU_26370
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Entry
SGLAU_26370 CDS
T03327
Symbol
tcmN
Name
(GenBank) Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN
KO
K15886
multifunctional cyclase / dehydratase / O-methyltransferase [EC:
2.3.1.235
]
Organism
sgu
Streptomyces glaucescens
Pathway
sgu01056
Biosynthesis of type II polyketide backbone
sgu01057
Biosynthesis of type II polyketide products
sgu01100
Metabolic pathways
sgu01110
Biosynthesis of secondary metabolites
Module
sgu_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
sgu_M00783
Tetracenomycin C/8-demethyltetracenomycin C biosynthesis, tetracenomycin F2 => tetracenomycin C/8-demethyltetracenomycin C
Brite
KEGG Orthology (KO) [BR:
sgu00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
SGLAU_26370 (tcmN)
01057 Biosynthesis of type II polyketide products
SGLAU_26370 (tcmN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
sgu01008
]
SGLAU_26370 (tcmN)
Enzymes [BR:
sgu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
SGLAU_26370 (tcmN)
Polyketide biosynthesis proteins [BR:
sgu01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Decaketide PKS
SGLAU_26370 (tcmN)
Polyketide tailoring proteins
Methylase
SGLAU_26370 (tcmN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Methyltransf_2
Polyketide_cyc
Polyketide_cyc2
Methyltransf_25
MTS
Motif
Other DBs
NCBI-ProteinID:
AIS01212
UniProt:
A0A089XH06
LinkDB
All DBs
Position
6014888..6016372
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AA seq
494 aa
AA seq
DB search
MAARTDNSIVVNAPFELVWDVTNDIEAWPELFSEYAEAEILRQDGDGFDFRLKTRPDANG
RVWEWVSHRVPDKGSRTVRAHRVETGPFAYMNLHWTYRAVAGGTEMRWVQEFDMKPGAPF
DNAHMTAHLNTTTRANMERIKKIIEDRHREGQRTPASVLPTELHAQQLLLLAASGRLARI
VHVLTELRIADLLADGPRHVAELAKETDTHELSLYRVLRSAASVGVFAEGPVRTFSATPL
SDGLRTGNPDGVLPLVKYNNMELTRRPYDEIMHSVRTGEPAFRRVFGSSFFEHLEANPEA
GEFFERFMAHWSRRLVLDGLADQGMERFSRIADLGGGDGWFLAQILRRHPHATGLLMDLP
RVAASAGPVLEEAKVADRVTVLPGDFFTDPVPTGYDAYLFKGVLHNWSDERAVTVLRRVR
EAIGDDDARLLIFDQVMAPENEWDHAKLLDIDMLVLFGGRERVLAEWRQLLLEADFDIVN
TPSHTWTTLECRPV
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
atggcagcgcgcacggacaactccatcgtcgtcaacgcgccgttcgagctcgtctgggac
gtcaccaacgacatcgaggcatggccggagctgttctccgagtacgccgaggcggagatc
ctccggcaggacggcgacggcttcgacttccggctcaagacccgccccgacgcgaacgga
agggtctgggagtgggtctcccaccgtgtgcccgacaagggctcccgcacggtccgggcg
caccgcgtcgagaccgggcccttcgcctacatgaacctgcactggacctaccgggccgtg
gccgggggcaccgagatgcggtgggtgcaggagttcgacatgaagcccggggccccgttc
gacaacgcgcacatgaccgctcacctcaacacgacgacacgggcgaacatggagcgcatc
aagaagatcatcgaggacaggcaccgggaaggacagcggaccccggcgtccgtcctgccc
accgaactgcacgcccagcaactgctgttgctggccgcctccgggcgcctggcgcggatc
gtccacgtgctgaccgagctgaggatcgccgatctcctcgccgacggcccccgtcacgtc
gcggaactggccaaggagacggacacccacgagctctccctctaccgcgtcctgcgcagc
gccgcctccgtcggcgtcttcgcggaggggcccgtcaggaccttctccgcgacgcccctg
tcggacggactgcgcaccggcaacccggacggtgtgctgcccctggtgaagtacaacaac
atggagctgaccaggcggccctacgacgagatcatgcacagtgtgcgcaccggcgaaccg
gccttccggcgggtgttcggcagctcgttcttcgagcacctggaggccaacccggaagcc
ggcgagttcttcgagcggttcatggcccactggagccgccggctcgtcctcgacggactc
gccgaccagggcatggagcgcttctcgcgcatcgcggacctcggcggtggcgacggctgg
ttcctcgcccagatcctccggcgccacccgcacgccacgggcctgctcatggacctcccg
cgggtggccgcgtcggccggccccgtcctggaggaggccaaagtcgccgaccgggtcacc
gtgctgcccggcgacttcttcacggaccccgtccccaccggctacgacgcctacctcttc
aagggcgtgctgcacaactggtccgacgagcgggccgtgaccgtgctgcgccgggtccgg
gaggccatcggcgacgacgacgcacgcctgctgatcttcgaccaggtcatggcccccgag
aacgagtgggaccacgccaagctgctggacatcgacatgctggtgctcttcggaggccgc
gaacgggtgctggccgagtggcggcagctgctgctcgaggcggacttcgacatcgtcaac
acgccctcccacacctggaccacgctggagtgccgccccgtctag
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