KEGG   Sarcophilus harrisii (Tasmanian devil): 100932451
Entry
100932451         CDS       T02286                                 
Name
(RefSeq) steroid 21-hydroxylase isoform X1
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00140  Steroid hormone biosynthesis
shr01100  Metabolic pathways
shr04925  Aldosterone synthesis and secretion
shr04927  Cortisol synthesis and secretion
shr04934  Cushing syndrome
Module
shr_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:shr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100932451
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    100932451
   04927 Cortisol synthesis and secretion
    100932451
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100932451
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:shr00199]
    100932451
Enzymes [BR:shr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     100932451
Cytochrome P450 [BR:shr00199]
 Cytochrome P450, animal type
  CYP21 family
   100932451
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 100932451
NCBI-ProteinID: XP_031820999
Ensembl: ENSSHAG00000009476
LinkDB
Position
4:complement(284928522..284941042)
AA seq 481 aa
MLLSVVLLLVLLAALRWLWMELTVSPHHFPPLVPGFLHFIHSDFPSHFLSLAQKYGPLYR
LHLGMQEVVVLNSKKAIEEAFMKKWIDFSGRPQTFTIQLVSNDSQDLSLGDYTPLWKAHR
KLARSALLYVQNSMEPLVGQMVQDLCKKLLAQAGSPVSISEEFSMFTCSIICFLSFGEKR
KSSVQEINSCIEELMIAWDCWQVQILNFLPFLRFFPNPGLRKLRQIIKKRDGIVQKQLRW
HKETMVEGQTRDLTDYMLQKLREQGEGQGQLSEGHVHMALVDFFIGGTETTASTLTWAVA
FLLHHPEIQRRLQEELDQELGPGFSGSPPNYQDRARFPLLNATITEVLRLRPAAPLALPH
CTKQPSSICGFDIPKDTIIIPNIFGAHHDDSVWAQPYDFRPDRFLEPELSPSGIPFSCGA
RVCLGEALARLELFLILAHLLQAFTLLPVIEGSHNLPSLKPTFGSNIKAQDFQVRLLPRL
E
NT seq 1446 nt   +upstreamnt  +downstreamnt
atgctgctttctgtggtcctgctgctggttctgctagctgccctaaggtggctatggatg
gaactgactgtctcaccccatcacttcccacctctagtccctggttttcttcacttcatc
cactctgatttcccaagccattttttgagccttgcacagaaatatgggccactctatcgg
cttcaccttgggatgcaagaagtggtggtgctaaattccaagaaggcaattgaggaggct
ttcatgaagaaatggatcgatttttcagggagaccacaaacattcactattcaattggta
agcaacgacagccaggatctgtctctgggggattacacgccactctggaaggcccacagg
aaactggcccgttctgctcttctgtatgtccagaatagcatggagcctctcgtgggacag
atggtacaagacttgtgtaagaagctccttgcccaggctggctctcctgtgagcatatct
gaggagttttccatgttcacttgtagcatcatctgcttcctcagttttggagaaaagaga
aagtcttcagttcaggaaattaacagctgcattgaggaattgatgatagcctgggactgt
tggcaagtccagattttgaacttcctaccctttctcaggtttttccccaacccaggtctc
aggaagctgaggcagataataaagaaacgggatgggattgtgcaaaagcaactgagatgg
cacaaggagacaatggtggaaggacagactcgggatttgactgattatatgctacagaaa
ctcagggaacaaggagaagggcaaggtcagctttctgagggacatgtacacatggcttta
gtggacttcttcattggaggcacagagaccacagcatccaccctcacctgggcagtggcc
ttcctgcttcatcacccagagatacaaaggcggctgcaagaagagttggatcaagagctg
ggaccaggtttttcaggaagccctcccaactatcaagacagagctcggttccccctgctc
aatgctacaattaccgaggtactccggctaagacctgcagcccccttggcccttccacac
tgcaccaaacagcctagcagcatatgtggttttgacatccctaaggataccattattatc
cccaacatctttggtgctcaccatgatgacagtgtttgggcacagccatatgacttccgg
cctgatcgtttcttggagccagaactgagtccgtcagggatcccattcagctgtggggcc
agggtgtgcttgggagaggctctggctcgcttagagctcttcttgatcctggctcacctg
ctccaagctttcacactactgcctgtaattgagggcagccataatctgccttctctgaag
cccacttttggaagcaatataaaggcccaagactttcaagtgcggctgctgcctcggctg
gaatga

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