Scomber japonicus (chub mackerel): 128371656 Help Entry 128371656         CDS       T09718                                  Name (RefSeq) ryanodine receptor 1-like   KO K04961   ryanodine receptor 1 Organism sjo  Scomber japonicus (chub mackerel) Pathway sjo04020   Calcium signaling pathway sjo04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sjo00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     128371656    04020 Calcium signaling pathway     128371656  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:sjo01009]     128371656   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:sjo04147]     128371656    04040 Ion channels [BR:sjo04040]     128371656 Protein phosphatases and associated proteins [BR:sjo01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      128371656 Exosome [BR:sjo04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    128371656 Ion channels [BR:sjo04040]  Voltage-gated cation channels   Ryanodine receptor    128371656 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  128371656 NCBI-ProteinID:  XP_053188001 LinkDB All DBs Position 13:complement(16297493..16346478) Genome browser AA seq 5026 aa AA seqDB search MAEGADEEEIQFLRTDDQVVLQCTASILKEQIKLCLSCEGFGNRLCFLETTSNAQNVPPD LAICCFILEQSLSVRALQEMLSNTSVDESSQGGGHRTLLYGHAILLKHTHSSMYLCCLTT SRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLS YASGDLMVDASFMQTLWTMTPVMSGCELAEGFLTGGYVLRLFHGHMDECLAIPGADQGDE RRVAHYEGGAVCSHARSLWRLEPLRIGWSGSHIKWGQSFRIRHITTGRYLCLDEEKGLLL VDPEKANSKMSAFCFRISKEKIEVTQKRDVEGMGIPEIKYGESMCFVQHVSTGLWLTYAA VDAKSARLGPLKRKAILHKEGHMDDALTVARSQTEESQAARMIHSTTGLFNQFIKGLDAL SGKNKSANPPSLPVDTVVLSLQDLIFYFRPPEEELEHEDKQFKLRSLKNRQNLFQEEGMI TLVLDCVDRLNVYNTAAHFSEYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFCDNL DWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLC SLCVCNGVAVRSNQNLITENLLPGRDLLLQTNIINYVTSMRPNIFLGTCEGSTQYKKWYF EVMVDHVEPFRTAQPYHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSG RVPRHVATPNHHILAGEDVVSCCLDLSVPSISFRINGHPVQGMFENFNLDGLFFPVVSFS AGVKLRFLLGGRHGDFKFLPPPGYAPCYEAVLPRDRLRIEPIKEYKHDFNGVRNLLGPTQ SLSHTAFTPCPVDTIQIVLPPHLERIREKLAENSHELWAVTRIEQGWTYGPFRDDNKKLH PCLVDFQSLPEPEKNYNLAMSGETLKTLLALGCHVGMGDEKAEENLKRTKLPKTFMQSNG YKPAPLDLNHVKLTPNQNTLVERLAENGHNVWARDRVRQGWTYSIVQDIMNKRNPRLVPY NLLDEKTKKTNRDTVCAAVRTLIGYGYNIEPPDQESGHGPGSGRGDKIRVFRAEKCYGVT QGKWYFEFEAVTVGEMRVGWARPSVRADTELGADELAYVFNGFKAQRWHVGNEPFGRQWL SGDVVGCMIDLTEMNIMFTLNGEMLISDSGSEMAFKDIEIGEGFIPVCSLGLSQVGRINL GQNVSSLRYFTICGLQEGFEPFAINMKRDITMWFSKSLPQFIAVPTEHPHIEVSRVDGTV ETAPCIKVTHKTFGSQNANTDLLFFRLSMPVEFHETFKVPAGTTLLTRPLTIPEDEVVEV DPDSDFEILKKSASRKEQEEEKKESSVPKESPAIKNGENEKDASTEKSKKKGFLFKAKKA ALISPPPVVPTMPRLMEDVVPDDRDDVDIILNTTTYYYSVRVFAGQEPGGVWVGWITPDY HQYDPHFDLSKVRNVTVTVGDDKGNIHDSIKRSNCYMVWGGEFSSSQQTRVSQEDFVIGC LLDLDTGLMTFTANGKEINTFYQVEPSTKLFPAVFVLPSSQNMIQFDLGKLKNIMPISAA MFRSERKNPVPQCPPRLDVQMLTPVIWSRMPNDFLVPDTGRVSERLGWMVLCQEPLTMMA LHIPEENKCIDILELSERMDLLKFHYHTLKLYGSVCALGNNRVAHALCSHVDESQLFYAI ENTYLPGPMRSGFYDLLISMHLESAKRNRLGTNKEFIVPMTDQTRSITLYSDKSHALPGV GLTTCLRPKLHFSSVGFVGTDPDIYTLSPVVPLQVLKTKALNMLIEAVQDGSQAMRDPVG GSVEFHFVPILKLISTLLIMGVFDDDDVTHILEMIEPTVFSEEEEEELEEEEELEEIESD TAHEEIVDETEQVNGEKGAEETEKETKPEEASGETKEEPLEQGLFQMKLPESVKLQMCTL LQYFCDCELRHRVEAITAFSDQFVSQIQSNQRHRYNELMLAFTMSAAETARKTREFRSPP QEQVNMLMNFKNCAEDEECPIPDEVRESLLAFHNALLAHCGVHIEEEEQEEEVDNSLRGR LRRMLEKVKTFREKKVEVEPEPQEDKKPSTLQELISHTMIHWAQESFIQNPELVRMMFSL LHRQYDGLGELIRALPKAYTINAVSIQDTMDLLECLGQIRSLLIVQMGPEEERLMIQSIG NIMSNKVFYQHPNLMRALGMHETVMEVMVNVLGGGDSKEIRFPRVVTNCCRFLCYFCRIS RQNQRSMFDHLSYLLQNSGIGLGMRGSTPLDVAAASCIDNNELALALQEQDLEMVVKYLA GCGLQSCPMLLAKGYPDIGWNPCGGEKYLDFLRFAVFVNGESVEENANVVVRLLIRRPEC FGPALRGEGGNGLLAAIEEAIKISEDPARDGPSVKKDRRFPMFGGEEQHEENKVHLGNAI MSFYSALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLEDLVGVISLPVQIPCFGKD NSIIEPKMSASFVPDHKAPMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRAAASLDTTAFS TTEMALALNRYLCSAVLPLITKCAPLFAGSDHRAIMIDSMLHTIYRLSRGRAFTKAQRDI IEECLMALCKHLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPNGWA NFGIASEEELHLTRKLFWGIFESLAHKKFDAEIFKISMPCICAIAGAIPPDYVDASYSSK TEKKASVDAEGNFDPKPVETTNTIIPERLDPFINRYAEYTHDRWAFEKIQNNWSYGEVLD ENAKTHPMLRPYKTFSEKDKEIYRWPIKESVKAMLAWEWTLDKAREEEESEKKKAVSRKI SQTAQATYDPSHGYSPQPIDVSHMALSRDLQSMAEQLAENYHNTWGRKKKLELQSKGGGS HPLLVPYDTLTAKEKARDREKAYELLKFLQLNGYAVTRGLKDMESDISSIEKRFAYGFLQ KLLKWMEIAQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILMPLINQYFKNHCLYFLSTP AKVLGSGGHSSNKEKEMIASIFCKMSALVRHRVSLFGTDASGIVNCLHILARSLDARTVM KSGPEIVKAGLRSFFESAADDIEKMVENLKLGKVSKGNQQVKGVSQNINYTTIALLPVLT SLFDHVAQHQFGDDVMLDDLQMSCYRIMCSIYSLGTVKNPHVERQRPALGECLAHLAAAM PVAYLEPNLNEFNAFSVYTTKTPRERAILGLPNEVQELCPDIPELDALLKDIGDLAESGA RYTEMPHVIEITLPMLCNYLPRWWERGAENSPEMEGRVCTEVTSEHLNQLLGSIMKIVVN NLGIDEASWMKRLAVFSQPIVSRAKPEMLKSHFIPTMEKLKKRTSKVVAEEDHLRMEGKS EGDEEDGTIRDEFAVLCRDLYALYPLLIRYVDNNRARWLTCPDPDAEELFRMVGEVFIFW SKSHNFKREEQNFVVMNEINNMSFLTADSKSKMSKGGSSDTERTKKKRRGDRYSVQTSLI VAALKKMLPIGLNMCSPADQELINLAKIRYSLRDTDEEVREFLQNNLHLQGKVDNPSMRW QMALYKEMAGKAEDADAPIKVVKRVQEVSAVLYHLEVTEHPFKSKKMVWHKLLSKQRRRA VVACFRMTPLYNIPRHRASNMFLEGYKRNWLHTEGYSFEDRMIDDLSKAMEQEEGDEEEE KETKPDPLHQLILHFSRTALTEKSKLDTDHLYMAYADIMAKSCHIGEEEEGGDEMVENAE DEMSFEVRQSELEKEMEKQRLLYQQARLHNRGTAEMVLQMISACKGETGPMVSTTLKLGI SILNGGNCEVQQKMLEYLRDKKDVGFFLSVQSLMQTCCVLDLNAFERQNKAEGLGMVSEE GTNLNLDRDEKVMSDDEFTCDLFRFLQLLCEGHNNDFQNYLRTQTGSTTTINIIICTVDY LLRLQESISDFYWYYSGKDIIDEPGKKNFSKAMTVAKQIFNSLTEYIQGPCTGNQQSLAH SRLWDAIVGFLHVFAHMMMKLAQGKDSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTI ARQMVDMLVESSSNVEMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFQKAMDSQ KQYSPSEIQFLLSCSEADENDMINYEEFANRFQEPAKDIGFNIAVLLTNLSEHVPHDTRL QNFLGQAESVLNYFRPFLGRIEIMGASRKIERIYFEISEVNRRQWEMPQVRESKRQFIFD VVNEGGESEKMEMFVNFCEDTIFEMNIASQISEQEEEEKGEEDDEVDEGGGEGSPVGAAS GGGDEDTNGEEVQPESSSAFADFINSVLSFFSIFTFRNLRRQYRRVRKMTLKEIVVALST FFWTILMSILHFIYNVCKGFFMIIWQTLFGGGLVEGAKNITVTEILASMPDPTQDDVHGD GPGEPRTGEEQDTGGVMDTGETGSGEEEEEDTQEKEGGRVPGVDAPGGLGDMGVEATVEP PTPEGTPITKRKMPPEEPDASQKPPEPVPVEEPVPEPEKADVETGEKAEKEPETKEPEKP EAPKKKATKKEKKPRGAEGFQIWTELETQRMKFMNYLSRNFYNLRFLALFLAFALNFILL FYKVSDTPPEGDEMEGSGLSEGSGMFEGSGLFEGSGEEAEGSGMSEGDEDEEDMPIYFYL EESTGYMQPTLSFLALLHTVISFICIIGYNCLKIPLVIFKREKELARKLEFDGLYITEQP EDDDIKGQWDRLVLNTPSFPNNYWDKFVKRKVLDKYGDIYGRERIAELLGVDLASLDVSQ QHEKKQEEPDNSVFAWATSIDIKYQIWKFGVVFTDGTFLYLCWYLIMSFFGHYNNFFFAC HLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDE PDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAI IQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTFDEHNLANYMFF LMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS NT seq 15081 nt NT seq  +upstreamnt  +downstreamnt atggcagagggtgcagatgaagaagagattcagttcctgcgtactgatgatcaagtggtg ctgcagtgtactgcctctattcttaaagaacagatcaaattgtgtctgtcttgtgaagga tttgggaatcgtctctgtttccttgaaaccacatcaaacgctcagaatgtccctccagac ctggctatctgctgcttcatattggagcagtccttgtcggtgcgggcattgcaggaaatg ttgtccaatacttctgtggatgagtcttcacagggtgggggtcacagaacactactgtat ggacatgccatcctcctgaaacacacccattccagcatgtacttgtgctgcttgactact tcgcgctcactgactgacaaattggcttttgatgtgggcttacaagaggactccacaggt gaggcctgctggtggaccatccatccagcctccaagcaaaggtctgaaggtgagaaggtc agggtgggagatgacctcattcttgtcagtgtttcttcagagcgatacctgcatctctcc tatgccagtggtgacttgatggtagacgcttccttcatgcagacactgtggacaatgacc ccagtgatgtctgggtgtgagctagctgaaggttttctgactggaggttatgtgctcagg ctgtttcatggtcacatggatgagtgtttggcaatcccaggcgctgaccaaggagacgag cgcagagttgctcattatgagggaggggctgtttgcagtcatgctcgatccttatggaga cttgagccattacgcattggatggagcggtagtcacattaaatggggccagtccttcagg atacgtcacataacaacaggcagatacctttgccttgacgaagagaaaggactgctgttg gtggacccggagaaggcaaattccaaaatgtcagccttctgcttcagaatttcaaaggaa aagattgaagtcacccagaagcgagatgtggaaggcatgggcatacctgagattaagtat ggagagtccatgtgctttgtacaacatgtttcaactggtctctggctaacgtatgctgcc gttgatgctaaatctgctcgtctgggtcctctgaagagaaaggccatacttcataaagaa ggtcacatggatgatgctctcacagtggctcgatcccagactgaagagtcacaagcggcc agaatgattcacagcacaacaggcctcttcaaccagttcatcaaaggtctagatgctctg agtggaaaaaacaagtctgccaatcccccatctctgcctgtggacacagtggtgctttcc ctgcaggacctaattttctacttccgaccccctgaggaggagcttgagcacgaggacaaa caattcaagcttcgttccctcaagaacagacagaacctctttcaagaggagggaatgatt actcttgttctggactgtgttgatcggctcaatgtctacaacacagcagcccacttctca gagtatgctggggaggaagctgcagagtcatggaaggagatagtaaatctactgtatgaa ttgctagcttctttgatcagaggtaatcgtgctaactgtgctctgttctgcgataacctg gactggctggtcagtaaattggatcgtttggaggcatcttcaggaatccttgaggtgttg tattgtgttctgattgagagcccagaggtgctgaatatcatccaggagaatcacatcaaa tcaatcatctccctgctggataaacatgggcgcaatcataaggtcttggatgtgctctgt tctctctgtgtatgtaacggggtggctgtgagatcaaaccagaatctcatcacagagaat ctgcttccaggtcgtgacctcctacttcaaacaaacattatcaattatgtaaccagcatg agacccaacattttccttggaacatgtgaaggatccactcagtataaaaagtggtatttt gaagtgatggtggaccatgtggagccattccggacagctcagccatatcacttgcgtgtg ggttgggctctgacagagggctacagtccttaccctggtggaggggagggctggggaggc aatggtgttggggatgacctctactcctacggttttgatgggcttcacctctggtcagga cgtgttccgcgtcatgttgccacacccaatcaccacatcctagcaggagaggatgtggtc agctgctgtttggatctgagtgtgcccagtatttccttccgtatcaatgggcatcctgtt cagggcatgtttgagaacttcaacctggacggcctcttcttccctgttgtcagcttctct gcaggcgtcaagttgagatttcttcttggaggtcgacatggagatttcaagttcctacca cccccaggctatgctccatgttacgaggcagtgctgcccagggatcgtttgcgaattgag cccatcaaggagtataagcacgatttcaatggtgtccgcaacctgttgggtccaacacag tccctctcacatacggctttcactccttgccctgtggacactatacagattgtacttcct cctcatttggagcgcattcgagagaagctagcagaaaatagccatgagttatgggctgtt acccgcattgaacaagggtggacctatggaccatttcgtgatgacaacaagaagcttcac ccctgcctggtagatttccagagtctgcctgaaccagagaaaaactacaatttagcaatg tcaggagagacactcaagactctgctggcactgggctgtcatgtaggaatgggagatgag aaagctgaggagaatctgaaaaggaccaagcttcccaaaactttcatgcagagtaatggt tataagccagcccctctggacctcaaccatgtcaagctgactcctaatcagaacactcta gtggagagactggcagaaaatggacacaatgtatgggcaagagaccgtgttcgccagggc tggacatatagtattgtgcaggatattatgaacaagcgtaatccccgtctggtaccttac aacctccttgatgaaaagaccaaaaagaccaacagagacacagtttgtgcagctgttcgc actctcatcggctatggttacaacatagaaccacctgaccaggagagcggacatggtcca ggcagcggccgtggagacaaaatcagagtgttcagagcagagaagtgttacggtgtcaca caggggaagtggtacttcgagtttgaggctgtgacagtcggggagatgagagtgggctgg gccaggcccagtgttcgtgccgacactgaacttggtgcagatgaattggcatatgtcttc aatggcttcaaggcccaacgttggcatgtgggaaatgagccatttggtcgtcagtggcta tctggtgatgtggtgggttgtatgattgacctcacagagatgaacatcatgttcacactc aatggggaaatgttgatcagtgactcaggctcggagatggcctttaaggatattgagata ggagagggctttatacctgtgtgcagtctgggcttatcccaggtcggcaggatcaactta ggtcagaacgtcagcagtctccgttacttcaccatctgtggtctgcaggagggatttgaa cctttcgctatcaatatgaaaagagacattaccatgtggttcagcaagagcctccctcag tttatcgctgtgcccactgaacatcctcacattgaggtgtcccgcgtggatgggacagta gaaactgctccttgtataaaagtgacccacaagacatttggatctcagaacgccaacaca gatctgctgttcttcaggctcagcatgccagttgagtttcatgagactttcaaagtccca gcagggaccaccctcctcactcgtcccctgaccatccctgaggatgaagtggtagaggtt gacccagactctgactttgaaatactcaagaagtcagcgagtcgcaaagagcaggaagag gagaagaaagaatcgtctgtgcctaaggagagccctgccatcaaaaatggagagaatgag aaggatgcctcaactgagaaaagcaagaagaagggattcctgttcaaggccaaaaaggcg gcattaatatctccacctcctgttgttcccacaatgcctcgcttaatggaggatgtggtg ccagatgacagggatgacgttgacatcatcctcaacactactacatactattattctgtg cgagtgtttgcgggccaggagcctggtggcgtgtgggtaggctggatcacacctgactat caccaatacgacccacattttgacctcagcaaagtgagaaatgtaacagtcactgtaggt gatgataaaggcaatatacatgacagcataaaacgtagtaactgctacatggtatgggga ggagagttcagcagctctcagcagacccgagtcagtcaggaagattttgtgatcggctgt ctccttgatttggacacgggactcatgactttcactgctaatggaaaagagataaacaca ttttaccaggtggagccctccacaaaactgttcccagctgtctttgtcctgccttcaagt cagaatatgattcagtttgatctcggcaagcttaagaacattatgccgatctcagctgct atgttccgaagtgaacgcaagaaccctgtcccccagtgccctcccagactggatgtccaa atgttaacaccagtcatctggagccggatgccaaacgacttcctggtcccagacacagga cgtgttagtgaaagactgggttggatggtgctgtgccaggagccactcaccatgatggcc cttcacatcccagaggagaacaagtgcattgacatcctggagttgtctgaacgaatggac ttgctgaagtttcactatcatactctgaagttgtacggctcagtgtgcgctctaggaaac aaccgcgtggctcatgccctgtgcagccatgtggatgaatcgcagctcttctatgccata gagaacacctacctacccgggccaatgaggagcggcttctatgacctgctcatcagcatg cacctggagtcagctaagaggaaccgcctgggaaccaataaggaattcatagttccaatg acagaccaaacacgcagtatcaccttgtactctgacaaatcacatgctttacctggggtt ggcctcacaacatgtcttcgtcccaaactccatttttcctctgttgggtttgtgggaacg gatccagacatctacaccctgagtccagtcgtccctttacaggtgctgaagaccaaagcc ctaaacatgttaatagaggctgtccaagatggaagtcaagccatgagagatcctgttggg ggcagcgttgagtttcattttgttccaatcctgaaactcattagcaccctcctcatcatg ggtgtgtttgatgatgatgatgtcacacacatcctggagatgattgagcccacagtcttc agtgaggaggaggaggaagaactggaggaagaggaagaattagaagagatagaatctgac acggcacatgaagaaattgtggatgagacagagcaagtaaatggcgaaaaaggagctgag gaaacagagaaagagacaaaacctgaagaggcgagtggtgagaccaaagaagaacctcta gagcaaggacttttccagatgaagctaccagagtctgtcaaactgcagatgtgtactcta ctgcagtatttctgtgactgtgagctacgtcacagagtggaggccataactgccttttca gaccaatttgtcagccaaatacagtccaaccagagacatcgctacaatgaacttatgctg gctttcaccatgagtgctgccgagactgcccgcaagacccgtgaattccgctccccacct caggagcaggtcaacatgctcatgaacttcaagaactgtgcagaggatgaggagtgcccc attccagacgaggtccgcgaatctctcctggcttttcacaatgctctgctggcacactgt ggtgttcatatcgaggaagaggagcaagaggaagaagtggataattctctccgtggacga ttgcgccgtatgctggaaaaggtgaaaactttccgtgagaagaaagtagaggtggaacct gagccacaggaggataaaaaaccaagcaccttgcaggagttgatttcccatactatgatc cactgggcgcaggagtcatttattcagaaccctgagctagtgcgtatgatgttcagcctc cttcacagacagtatgatgggctaggtgagcttatacgtgcccttcccaaagcctacacc atcaacgcagtctcaattcaggacactatggacctgctggagtgcttaggccagatccgc tccctgcttattgtccagatgggtccagaagaggagagacttatgattcaaagcattggg aacatcatgagtaacaaagttttctatcaacaccccaacttgatgcgagctctgggcatg catgaaactgtcatggaggtcatggttaatgtactaggtggtggggactcaaaggagatc agattcccccgagtggtgacaaactgctgccgtttcctctgttatttctgtcgtatcagt cgtcaaaaccagcgttctatgttcgaccacctcagctacctgttgcagaacagcggcatc ggccttggaatgcgcggctctacccccttggatgtggctgcagcctcttgcattgacaac aatgagctggcattagctctgcaagagcaagacttagaaatggtggtgaagtatttggct ggatgtggtcttcagagctgtccaatgctcttagctaaaggctaccctgacattggctgg aacccttgtggtggagagaaataccttgactttcttcgttttgctgtattcgtcaatgga gagagcgtagaagaaaatgccaatgtggtggtacgccttctcattcgcagacctgaatgc tttggtccagctctgagaggggagggtggtaatggtctgctagctgctattgaggaggct attaaaatatcagaagaccctgcaagagatggccctagtgttaagaaagacagacgtttt cccatgtttggaggagaggagcagcatgaagagaacaaggtgcacctgggaaatgccatc atgtccttctactctgccctcattgacctgttgggacgctgtgctccagagatgcattta attcaagctggaaagggtgaggctttgaggatcagggctatcctgaggtctctggtccct cttgaggatctggtgggagtcatcagccttcctgttcagattccttgttttggaaaagac aatagcatcattgaaccaaagatgtcagctagttttgtgcctgatcacaaggctcccatg gtgctgttcctggacagagtgtatggtattgacaaccaagattttctgctccatgtgttg gaggtgggcttcctgcctgacatgagggccgctgcctctcttgacacgactgctttcagc accacagagatggctctcgctttgaaccgttacctgtgttctgctgtgttgccactcata acaaagtgtgccccactttttgctggcagtgaccaccgagccataatgattgactccatg ttgcacacaatctatcgtctgtctcgaggacgagccttcacaaaggcccaaagagacatc attgaagagtgcctcatggccttgtgcaagcatttacgcccatccatgcttcagcacctg ctacgacgactggtgtttgatgtgcccattcttaatgagtatgccaaaatgcctctgaag cttttgaccaatcactatgaacgttgttggaaatattattgcctcccaaatggctgggcc aactttggaattgcatcagaagaggagctgcatctgacccgcaaactgttttgggggatc tttgaatcccttgcacacaagaaatttgatgctgagattttcaaaatttcaatgccatgc atctgtgctattgctggagccattcctccagactatgttgatgccagctattcctccaaa acagagaaaaaggcatcagtagatgcagagggaaactttgatcctaaaccggtggagacc acaaacactatcatccctgagagactggatccctttatcaatagatatgctgaatataca catgatagatgggcttttgaaaagattcagaataactggtcatatggtgaggtgctggat gaaaatgcaaaaactcatcccatgctcagaccatacaaaaccttctcagagaaggacaaa gaaatctaccgctggccgatcaaagagtcagtcaaagccatgcttgcatgggagtggacc ttggataaagctagagaagaagaagagtcagagaagaagaaggcagtgtcacgaaaaatc tcacagactgctcaggcaacctatgaccctagccacggttacagtccacagcctattgac gtctcacatatggctctttcaagagacctgcagtctatggcagagcaactggcagaaaat taccataacacttggggacgaaagaaaaagttggagctgcagtctaaaggaggtggatca catcctcttctggtgccctacgataccctgacagccaaagaaaaggcacgagatagagag aaggcttacgagttgctcaaattcctgcagcttaatggatatgctgtcacaaggggcctg aaagatatggagtcggacatttcctccatcgagaagagatttgcgtatggtttcctgcag aagctgctgaaatggatggaaattgcccaagagtttattgctcatcttgaggctgtggtc agcagtggtcgtgtggaaaagtctcctcatgagcaggaaatcaaattctttgccaagatc ctgatgcccctaatcaaccagtatttcaaaaaccactgcctctacttcttgtcgacacct gcaaaagttctgggtagtggtggccattcttccaataaggagaaggagatgattgcaagt atcttctgtaaaatgtctgctctggtgagacacagagtttctctctttggaacggatgct tcaggaattgttaactgtcttcacattctggcacgatcactggatgcaaggacagtcatg aagtcagggcctgagattgtgaaagcagggctgcggtcattctttgagagtgctgctgat gatatagagaagatggtagagaacctgaaactgggcaaagtatctaaaggcaatcagcaa gtgaaaggtgtgtcccagaacattaactacacaaccattgccctgctgccagtgcttacc tccctgtttgatcacgttgctcagcaccagtttggagatgatgtcatgttggatgatcta cagatgtcgtgctatcgcattatgtgtagtatctactcactggggactgtcaagaatcca cacgttgagagacagagaccagctcttggagagtgtttggctcaccttgcagcagctatg ccagtggcttatttagagcccaatctaaatgagttcaatgctttctctgtctacaccaca aagacacccagggagagagccatcttgggtcttcccaatgaggtccaggaattatgtcca gatattccagagctggatgctttgctaaaggatattggggacttggcagagtcaggggct cgttatactgagatgcctcatgtgattgaaatcactttgcccatgctatgtaactatctg ccacgctggtgggagagaggagctgagaactcccctgagatggagggccgagtctgcact gaagtcacctcagaacatcttaatcagctgctgggcagcatcatgaaaattgttgtcaac aacttgggtatagatgaggcctcctggatgaagaggttggctgtgttctcacagcctatt gtgagcagggcaaaaccagaaatgctcaaatcccactttatcccaacaatggagaagctg aagaaacgcacttcaaaggtggtggctgaagaggaccatctgcggatggaggggaaatcg gaaggtgatgaggaagatggcactatacgtgacgagtttgctgtcctctgcagagacttg tatgccctctaccctctcctcatccgctatgtggacaacaacagggcgaggtggctgaca tgcccagacccagatgctgaagagctcttccgaatggttggagaagtcttcatattttgg tccaaatctcataacttcaagcgagaggaacagaactttgtggtgatgaatgagatcaat aacatgtcatttctcactgctgacagcaagagcaaaatgagcaagggtggcagctcagat actgaacgtaccaagaagaagagacgtggagatcgttactctgtgcagacttcactcata gtggctgccttgaaaaagatgcttcccataggcctcaatatgtgctctcccgccgatcag gagcttatcaacttggccaagatccgatattctttgagagacactgatgaagaagtaaga gagttccttcagaacaaccttcatcttcagggaaaggtggacaatccatccatgcgctgg cagatggccttgtacaaggaaatggcagggaaggccgaagatgctgacgcaccaataaaa gttgttaagagggtgcaggaggtgtctgctgtcctctaccaccttgaagtgacagagcat ccgtttaaatccaagaagatggtgtggcacaaacttttgtctaagcagagacgcagggct gtggtcgcttgctttaggatgacaccactatataacattccacggcacagagcttcaaac atgttccttgagggatacaaacgcaactggcttcacactgagggttactcatttgaggac aggatgattgatgacttgtctaaagccatggagcaagaggaaggagatgaagaggaggag aaagaaacaaagccagatcccctccaccaacttattctgcatttcagtcgcactgctcta acagaaaagagtaaacttgatacagatcatctttatatggcatatgcagatattatggca aagagttgccatattggtgaggaagaagaagggggagatgaaatggtggaaaatgctgag gatgagatgtcctttgaggtgcgacagtcagaactggaaaaagaaatggagaaacagaga cttctgtaccagcaggccagacttcataatcgtggtactgcagagatggtcctgcaaatg atcagtgcttgcaaaggtgagactggcccaatggtgtctacaaccctcaagttgggtatc tctattcttaatggaggaaactgtgaggttcagcagaaaatgttggagtacctgagggat aaaaaggatgttggtttctttttgagtgtccaatcattgatgcaaacatgctgtgtcctg gatctgaatgcttttgagaggcagaacaaggcagagggtctgggcatggtttcagaggag ggcaccaacttgaacctagatcgggatgaaaaagtcatgtcagacgacgagtttacctgt gacctcttccgtttcttgcagctgctttgcgagggtcacaataacgactttcaaaactac ttgcggacgcagacaggaagcacaactaccatcaacatcatcatctgtacggtagattac ctactccgactgcaggagtctatcagtgatttctactggtattactccggcaaggacatc atcgatgaaccaggcaaaaagaatttttccaaagccatgacagtggcaaaacagattttc aacagtctaactgaatacatccagggaccctgcaccggcaaccagcagtctctggcccac agcaggctgtgggacgctattgttgggttccttcatgtctttgcccacatgatgatgaag ctggcacagggtaaagactccagccagattggtctgctgaaggagctgcttgacctacag aaagacatggttgttatgttgctctcactgttagagggaaatgtggtgaatggtacaatt gcccgccagatggtggacatgttggtggagtcctccagcaatgtagagatgatcctcaag ttctttgacatgtttctcaaattgaaagacattgtggcttcagatgctttccgtgattac gtcacagaccctcgaggtctcatctccaagaaggacttccagaaggccatggacagtcag aaacagtactccccttccgagatccagtttctcttgtcttgctccgaagcagatgaaaat gacatgatcaattatgaggagtttgccaatcgcttccaagaaccagccaaggacatcggc ttcaacattgcagtactgctcaccaacttgtctgaacatgtcccccatgacacaaggctc caaaacttcctaggacaagcagaaagtgtgctgaactacttccgtcccttcctgggccga atcgaaattatgggtgccagcagaaagattgagcgtatctactttgaaatcagtgaagtc aaccgcagacagtgggagatgccccaggtcagagagtccaaacgtcagtttatctttgat gttgtcaatgagggcggtgaatcagagaagatggagatgtttgtcaacttctgcgaggac accatctttgagatgaatatagcttcacaaatatcagagcaggaagaagaggaaaagggg gaagaagatgatgaagtagatgaaggtggaggtgagggaagtccagtaggggcagcaagt ggaggaggtgatgaggacactaatggagaggaagtgcaacctgaatcaagttctgctttt gcagacttcataaacagcgtgttaagcttcttcagcatcttcaccttccgtaatcttcgc agacaatatcgcagggtgagaaagatgaccttaaaggagattgtggtggctttgtccact tttttctggaccatccttatgagtatactacacttcatttacaatgtgtgcaaaggcttc tttatgataatctggcaaacgctgtttggaggtggcttagtggagggagctaaaaatatc actgtgactgaaattctggcaagcatgccagatcccacccaggatgacgtacatggtgat gggccaggggagccgaggacaggggaggaacaagacactggaggagtgatggacactgga gagactggaagtggagaggaggaggaggaggatacccaggagaaagagggtgggagggta ccaggtgttgatgctccaggtggacttggagatatgggggttgaggcaactgttgaacct ccaactcctgaaggaacacccataacaaagagaaaaatgccaccagaagagcctgatgca agccagaaacctcctgaacctgtccctgtagaagaacctgttccagagcctgaaaaggcc gatgtagaaactggagaaaaagcagagaaagaacctgagaccaaagaaccagaaaagcca gaagcaccaaagaaaaaagcaacgaaaaaagaaaagaagccaagaggggcagaaggtttc caaatatggactgagctggaaacccaaagaatgaaattcatgaactacctctccagaaac ttctacaacctgcggtttttggctctgttcctcgcatttgccctcaacttcattctgctg ttttacaaggtgtctgacacccctcctgagggtgacgagatggaaggatctgggctgtca gaaggaagcgggatgttcgaaggctctgggttgtttgaaggctcaggggaagaggctgaa ggatctggaatgagtgaaggagatgaagatgaggaagacatgccaatttatttctattta gaggagagtactggctacatgcagcccacactgtccttccttgccttactgcacacagtc atctcattcatctgtattattggatacaattgcctcaagattcctctggtaatctttaaa agggagaaagaacttgcaagaaagttggaatttgatggtctctacatcactgaacagcct gaagatgacgatattaagggccagtgggacagactggtcctgaatacaccttctttccca aacaactattgggataaatttgtcaaacgaaaggttctggataaatatggagacatttat ggcagagaaagaattgctgaactcctgggagtcgatttagcctccctggatgtgagtcaa cagcatgagaagaaacaggaagaaccagacaactctgtgtttgcatgggcgacttccatt gacatcaagtaccagatctggaaatttggtgttgtgttcacagatggtaccttcctttat ctgtgttggtacctgatcatgtctttcttcggacattataacaacttcttcttcgcctgt cacttgctggatatcgccatgggtgtcaagacactgcgcactattctgtcttcagtcaca cacaatgggaaacagcttatgatgacagtgggcttgttggcagtagtggtgtacctgtac actgtagttgccttcaatttcttccgcaagttttacaacaagagtgaggatgaagatgaa cctgatatgaaatgtgatgacatgatgacttgttacctgttccacatgtacgtgggtgtg cgtgctggtggaggcattggagacgagatcgaggatcctgctggagatgaatacgagtta tatcgagtggtctttgatataactttcttcttctttgtcattgtcatcttgctggccatt attcagggtctgatcattgatgcctttggagaactcagagaccaacaggagcaggtcaag gaagacatggagacaaaatgcttcatatgtggcattggaagtgactactttgatactaca ccacacggctttgagacacacactttcgacgagcacaacctggccaattacatgttcttc ttaatgtaccttatcaacaaagacgagacagagcacactggacaggagtcatacgtctgg aagatgtaccaggagcgttgctgggacttcttccctgctggagactgtttcagaaagcaa tatgaggatcagctttcttag

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