KEGG   Salvia miltiorrhiza (redroot sage): 130986590
Entry
130986590         CDS       T09291                                 
Name
(RefSeq) putative bifunctional dihydrofolate reductase-thymidylate synthase isoform X1
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
smil  Salvia miltiorrhiza (redroot sage)
Pathway
smil00240  Pyrimidine metabolism
smil00670  One carbon pool by folate
smil00790  Folate biosynthesis
smil01100  Metabolic pathways
smil01232  Nucleotide metabolism
smil01240  Biosynthesis of cofactors
Module
smil_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:smil00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    130986590
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    130986590
   00670 One carbon pool by folate
    130986590
Enzymes [BR:smil01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     130986590
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     130986590
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-GeneID: 130986590
NCBI-ProteinID: XP_057766017
LinkDB
Position
5:complement(19616563..19621280)
AA seq 585 aa
MYCGLFNVKNSAIKIPLAAIDYTVQNSIFTLASHSLILRSLEACKRFTGQRFSSGYLVMG
GASNSNECTSSGEVPVSHRTYQVMVAATQDMGIGKDGKLPWRLPSDLKFFKDITMNTSDP
DKKNAVMMGRKTWESIPPQFRPLPGRLNVVLSRSGNSDVAAGSDNVIVCGSVSSALKLLG
EPPYSLSVEKVFLIGGGQILREALNAEECDAIHITEIRSHFECDTFIPPIDMLVYHPWYS
SFPIQENGINYCFATYVRLKTCNRNNSSHSIKPKLSYFSFLPKIIFEKHEEFLYLRLVQD
ILSNGNKKDDRTGTGTLSKFGCQMRFNLRKSFPLLTTKRVFWRGVVEELLWFISGSTNAK
ILQEKGIHIWDGNASREYLDSIALTDREEGDLGPVYGFQWRHFGARYTNMHADYTGQGFD
QLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFSQFYVANGELSCQMYQRSADM
GLGVPFNIASYALLTCMLAHVCDLVPGDFVHVIGDAHVYTTHISPLQDQLKKHPRPFPVK
YRIVYFCSKCQFMFVHILLYTCLFSVSHTPKILDDATRLYYFESF
NT seq 1758 nt   +upstreamnt  +downstreamnt
atgtattgtggattgttcaatgtaaaaaattcagcaattaaaatccctttggctgcaata
gactatactgttcagaatagtatatttactttggcttcacattcattgattttgcggtct
cttgaagcttgtaaacggtttacggggcaaagattctcttcaggatatttagtgatgggt
ggtgcttcaaattcaaatgaatgcacctctagtggcgaggtgccagtttcccatagaact
tatcaggttatggtagctgcaactcaagatatgggtatcgggaaagatggtaagttgcca
tggcgattgcccagtgatcttaaatttttcaaagatatcaccatgaatacatcggatccc
gataagaaaaatgctgtgatgatggggaggaaaacttgggaaagtattccccctcaattt
cgacctttgcctggtcggctcaatgttgtgctgtcacgttctggaaattctgatgttgct
gctggttctgataatgttattgtatgtggaagtgtttcgtcagctttgaaattgttggga
gaacccccttatagtttgtccgtagagaaggttttcctgataggaggtggccagattttg
agggaagcccttaatgctgaggaatgtgatgctattcacataactgaaatcaggagtcat
tttgaatgtgacacatttatacctcctattgatatgttagtttaccatccatggtactca
tccttccccattcaggagaatgggatcaattattgttttgcgacatatgtgcgactgaaa
acttgtaatcgcaataattcatcacattccataaagcccaaactttcatatttctctttc
cttcctaagattattttcgagaaacatgaagagtttctctacttgagactggttcaagat
atcctttctaatgggaacaaaaaggatgaccgcacagggactggcactctttcaaaattt
ggctgccagatgcgctttaacctgcgtaaatctttccctcttcttacaaccaagagggtt
ttctggcgcggagttgttgaagagcttttgtggtttattagtggttcaacaaatgctaag
attctacaagagaaagggatacacatatgggatggcaatgcatctagagaatacctcgac
agtattgctttgacggacagggaagagggagatttgggaccggtatacggtttccagtgg
agacattttggtgctagatacaccaatatgcacgcggactatacaggacaagggtttgat
cagttgctagatgtgattgataagataaagaataaaccagatgacaggcgtattatcctt
tctgcatggaatccttccgatcttaagttgatggctttacccccttgccacatgtttagt
cagttttatgtagccaatggtgagctatcttgtcagatgtatcaacgttctgctgatatg
ggtcttggggtgccatttaacattgcatcctatgctctgctgacatgcatgctagctcat
gtttgtgatcttgttcctggtgattttgttcatgtcattggagacgctcatgtttacaca
actcatatcagccctctgcaggaccaacttaaaaaacatccgagacctttcccagttaag
tatcgcattgtgtacttctgttctaaatgtcaatttatgttcgtacatattttattatat
acatgtcttttttctgttagtcatactccaaagatcctagatgatgctactagactttac
tattttgagtcattctag

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