KEGG   PATHWAY: spu00531
Entry
spu00531                    Pathway                                
Name
Glycosaminoglycan degradation - Strongylocentrotus purpuratus (purple sea urchin)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
spu00531  Glycosaminoglycan degradation
spu00531

Module
spu_M00076  Dermatan sulfate degradation [PATH:spu00531]
spu_M00077  Chondroitin sulfate degradation [PATH:spu00531]
spu_M00078  Heparan sulfate degradation [PATH:spu00531]
spu_M00079  Keratan sulfate degradation [PATH:spu00531]
Other DBs
GO: 0006027
Organism
Strongylocentrotus purpuratus (purple sea urchin) [GN:spu]
Gene
584769  hyaluronidase 1 [KO:K01197] [EC:3.2.1.35]
582946  hyaluronidase isoform X2 [KO:K01197] [EC:3.2.1.35]
575967  hyaluronidase-1 isoform X2 [KO:K01197] [EC:3.2.1.35]
115924575  hyaluronidase-like [KO:K01197] [EC:3.2.1.35]
575689  beta-glucuronidase [KO:K01195] [EC:3.2.1.31]
579992  iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
584730  iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
588631  iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
587680  iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
100892667  iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
115922305  iduronate 2-sulfatase-like isoform X1 [KO:K01136] [EC:3.1.6.13]
100892602  iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
588607  iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
115918435  iduronate 2-sulfatase-like [KO:K01136] [EC:3.1.6.13]
592184  alpha-L-iduronidase [KO:K01217] [EC:3.2.1.76]
115924180  alpha-L-iduronidase-like [KO:K01217] [EC:3.2.1.76]
583464  LOW QUALITY PROTEIN: arylsulfatase B [KO:K01135] [EC:3.1.6.12]
586205  arylsulfatase B [KO:K01135] [EC:3.1.6.12]
584709  arylsulfatase B-like [KO:K01135] [EC:3.1.6.12]
583878  arylsulfatase B [KO:K01135] [EC:3.1.6.12]
100891337  arylsulfatase B [KO:K01135] [EC:3.1.6.12]
591704  arylsulfatase B [KO:K01135] [EC:3.1.6.12]
115925932  LOW QUALITY PROTEIN: arylsulfatase B-like [KO:K01135] [EC:3.1.6.12]
587189  arylsulfatase J [KO:K01135] [EC:3.1.6.12]
115918901  arylsulfatase B-like [KO:K01135] [EC:3.1.6.12]
105439655  arylsulfatase J [KO:K01135] [EC:3.1.6.12]
586860  heparanase [KO:K07964] [EC:3.2.1.166]
763558  heparanase [KO:K07964] [EC:3.2.1.166]
589739  N-sulphoglucosamine sulphohydrolase [KO:K01565] [EC:3.10.1.1]
592189  N-sulphoglucosamine sulphohydrolase [KO:K01565] [EC:3.10.1.1]
115923568  N-sulphoglucosamine sulphohydrolase-like [KO:K01565] [EC:3.10.1.1]
590342  heparan-alpha-glucosaminide N-acetyltransferase isoform X1 [KO:K10532] [EC:2.3.1.78]
584064  heparan-alpha-glucosaminide N-acetyltransferase isoform X1 [KO:K10532] [EC:2.3.1.78]
752871  heparan-alpha-glucosaminide N-acetyltransferase [KO:K10532] [EC:2.3.1.78]
580105  alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
100893810  alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
115929153  alpha-N-acetylglucosaminidase-like [KO:K01205] [EC:3.2.1.50]
100891543  alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
579130  N-acetylgalactosamine-6-sulfatase-like [KO:K01132] [EC:3.1.6.4]
588014  N-acetylgalactosamine-6-sulfatase isoform X1 [KO:K01132] [EC:3.1.6.4]
587532  beta-galactosidase [KO:K12309] [EC:3.2.1.23]
115925974  beta-galactosidase-like [KO:K12309] [EC:3.2.1.23]
588183  N-acetylglucosamine-6-sulfatase isoform X1 [KO:K01137] [EC:3.1.6.14]
594823  beta-hexosaminidase subunit alpha isoform X1 [KO:K12373] [EC:3.2.1.52]
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526   
G00711   
G00872  DWA-2
G01391   
G01945   
G01977   
G02632   
G09660   
G10008   
G10505  Hyaluronic acid
G12336   
G13034   
G13035   
G13036   
G13037   
G13038   
G13039   
G13040   
G13041   
G13042   
G13043   
G13073   
G13074   
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
spu00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
spu00533  Glycosaminoglycan biosynthesis - keratan sulfate
spu00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
KO pathway
ko00531   
LinkDB

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