Streptomyces sp. RPA4-2: HEP85_21130
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Entry
HEP85_21130 CDS
T10422
Name
(GenBank) ketosynthase chain-length factor
KO
K05552
minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
srpz Streptomyces sp. RPA4-2
Pathway
srpz00253
Tetracycline biosynthesis
srpz01056
Biosynthesis of type II polyketide backbone
srpz01100
Metabolic pathways
srpz01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
srpz00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
HEP85_21130
00253 Tetracycline biosynthesis
HEP85_21130
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
srpz01004
]
HEP85_21130
01008 Polyketide biosynthesis proteins [BR:
srpz01008
]
HEP85_21130
Enzymes [BR:
srpz01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
HEP85_21130
2.3.1.260 tetracycline polyketide synthase
HEP85_21130
Lipid biosynthesis proteins [BR:
srpz01004
]
Polyketide synthase
Component type
HEP85_21130
Polyketide biosynthesis proteins [BR:
srpz01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
HEP85_21130
Nonaketide PKS
HEP85_21130
Decaketide PKS
HEP85_21130
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Motif
Other DBs
NCBI-ProteinID:
QIY63666
UniProt:
A0A6H1K989
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All DBs
Position
4793140..4794354
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AA seq
404 aa
AA seq
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MTTTVVVTGLGIAAPNGLGTQDYWAATRTGKNGIGRVTRFDPSSYPSTLAGEVPGFVAED
VLPSRLLPQTDHMTRMALVAADWALADAGIDPTELPQYDMGVVTASSSGGFEFGQGELEK
LWSQGSQYVSAYQSFAWFYAVNSGQISIRNGLKGPSGVIVSDEAGGLDAVAHGRRLIRKG
TPMIVSGGVDASVCPWGWVAQMAGGRLSTSDEPTRAYLPFDADASGHVPGEGGAILIMES
AESACARGARIYGEIAGYGSTFDPRPDSDREPGLRKAIELALADADVAPGDVDVVFADAA
GVPELDRIEAEAISAVFGVRGVPVTAPKTMTGRLYSGAAPLDIATALLAVEEGLIPPTVH
VDPDEEYGLDLVLTQSRPAQVRTALVVARGYGGFNSAVVVRAVD
NT seq
1215 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccacggtggtagtgaccggtctgggcatcgccgcccccaacggactgggcaca
caggactactgggccgcgacccggaccggcaagaacggcatcgggcgggtcacccgcttc
gacccgtcgtcctacccgtcgaccctggcgggcgaggtgccgggcttcgtcgccgaggac
gtgctgccgagccggctgctgccgcagaccgaccacatgacgcggatggcgctggtcgcc
gccgactgggcgctcgccgacgcggggatcgacccgacggagctgccgcagtacgacatg
ggcgtcgtcacggccagttcctcggggggcttcgagttcggccagggtgagctggagaag
ctgtggagtcagggcagccagtacgtctccgcctaccagtccttcgcctggttctacgcc
gtcaacagcggtcagatctccatccgcaacgggctgaagggtcccagcggcgtcatcgtc
agcgacgaggccggcggtctcgacgcggtggcgcacggccggcggctcatccgcaagggc
accccgatgatcgtctccgggggtgtcgacgcgtcggtctgtccctggggctgggtggcg
cagatggccggcggccggctgagcaccagcgacgaaccgacccgcgcctatctgcccttc
gacgccgacgcgtccggccatgtgccgggcgagggcggcgccatcctgatcatggagtcg
gccgagtcggcgtgcgcgcgcggcgcccggatctacggcgagatcgcgggctacggctcg
acgttcgacccacggccggacagcgaccgcgagcccggtctgcgcaaggcgatcgaactc
gccctcgccgacgcggacgtggcacccggggacgtcgacgtggtcttcgcggacgcggcc
ggcgtgccggagctggaccggatcgaggccgaggcgatctcggcggtcttcggtgtccgg
ggcgttccggtcaccgcgcccaagacgatgacgggccgactgtactccggcgcggccccg
ctcgacatcgccaccgccctgctcgccgtggaggagggactgatccccccgacggtgcac
gtcgacccggacgaggagtacggactcgacctggtcctcacccagtcgcggcccgcccag
gtgcgtaccgcgctggtcgtggcccgtggctacggcggcttcaactcggccgtcgtcgtc
cgcgccgtcgactga
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