KEGG   Streptomyces reticuli: TUE45_01569
Entry
TUE45_01569       CDS       T04246                                 
Name
(GenBank) Actinorhodin polyketide putative beta-ketoacyl synthase 2
  KO
K05552  minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
srw  Streptomyces reticuli
Pathway
srw00253  Tetracycline biosynthesis
srw01056  Biosynthesis of type II polyketide backbone
srw01100  Metabolic pathways
srw01110  Biosynthesis of secondary metabolites
Module
srw_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:srw00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    TUE45_01569
   00253 Tetracycline biosynthesis
    TUE45_01569
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:srw01004]
    TUE45_01569
   01008 Polyketide biosynthesis proteins [BR:srw01008]
    TUE45_01569
Enzymes [BR:srw01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     TUE45_01569
    2.3.1.260  tetracycline polyketide synthase
     TUE45_01569
Lipid biosynthesis proteins [BR:srw01004]
 Polyketide synthase
  Component type
   TUE45_01569
Polyketide biosynthesis proteins [BR:srw01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     TUE45_01569
    Nonaketide PKS
     TUE45_01569
    Decaketide PKS
     TUE45_01569
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_C_1
Other DBs
NCBI-ProteinID: CUW26856
LinkDB
Position
I:complement(1931836..1933050)
AA seq 404 aa
MKRAVVTGIGVVAPNGLTTEDFWAATLKGRSGIREVEFGDTRYSARFGGRITDFDDKRHI
PSRLLPQTDRMTRLALYAAESAFHDAELDPEAVAGYGSGVTLSNAAGGFALSHRELKKLW
GEGPKSVSAYLSFAWFYACNSGQISIRHGLRGPSAALVAEQAGGLDAIGYSRRSVRRGTR
MVLTGGVESALDPWGWISHISSGRVARPAAADRAFLPFGTDAAGYVPGEGGAVMVLEDRD
EADARRAPRRYGEIAGYAATFDPAPGTGRPPGLRRAAENALADAGLAPADIDVVFADGAG
SPDLDRAEAEAISAVFGPRAVPVSVPKALVGRLYAGGAPLDVATALLSIRDDVIPPVPAA
VEPDPEYGIDLVVGAPRHVPVRRALVLARGRGGFNSAVVVTAAA
NT seq 1215 nt   +upstreamnt  +downstreamnt
atgaagcgcgccgtcgtgacggggatcggggtggtcgcccccaacggcctgaccaccgag
gacttttgggccgccacgctcaaggggcgcagcggcatccgcgaggtcgagttcggggac
acccgctactcggcccggttcggcggccggatcacggacttcgacgacaagcggcacatc
cccagccggctgctcccgcagaccgaccggatgacccggctcgcgctgtacgccgccgag
tccgccttccacgacgccgaactggacccggaggccgtcgccggctacggcagcggcgtc
acgctgtccaacgcggcgggcggattcgcgctcagccaccgggagttgaagaagctctgg
ggcgagggcccgaagtcggtcagcgcctatctgtccttcgcctggttctacgcctgcaac
agcggccagatctccatccggcacgggctgcgcggaccgagcgccgcgctggtcgccgag
caggccggcggactcgacgcgatcggctactcgcggcgcagcgtgcgccgcggcacccgg
atggtgctgaccggcggcgtcgagtcggcactggacccgtggggctggatctcgcacatc
tccagcggccgggtcgcccggcccgccgcagccgaccgggccttcctccccttcggtacc
gacgccgccggctacgtccccggcgagggcggcgccgtcatggtgctggaggacagggac
gaggccgacgcccggcgggcgccgcgccgctacggcgagatcgccggctacgcggccacc
ttcgacccggcccccggcaccggccggccgcccggtctgcgccgggccgccgagaacgcc
ctcgccgacgccgggctggccccggccgacatcgacgtcgtcttcgcggacggcgccggc
agccccgacctcgaccgggccgaggcggaggcgatcagcgcggtgttcggcccccgtgcc
gtaccggtcagcgtgcccaaggcactggtcggccggctctacgcgggcggcgccccgctg
gacgtcgccaccgcgctgctgtccatccgcgacgacgtgatcccgccggtccccgccgcc
gtcgagccggacccggagtacggcatcgatctcgtcgtcggcgcaccgcgccacgtcccg
gtgcgccgggccctcgtcctggcccgtggccggggcggcttcaactccgccgtggtggtc
acggccgcggcctga

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