Symphalangus syndactylus (siamang): 129468378
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Entry
129468378 CDS
T10134
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform X1
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn04148
Efferocytosis
ssyn04330
Notch signaling pathway
ssyn04668
TNF signaling pathway
ssyn05010
Alzheimer disease
ssyn05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
129468378 (ADAM17)
04668 TNF signaling pathway
129468378 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
129468378 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
129468378 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
129468378 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ssyn01002
]
129468378 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ssyn04090
]
129468378 (ADAM17)
Enzymes [BR:
ssyn01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
129468378 (ADAM17)
Peptidases and inhibitors [BR:
ssyn01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
129468378 (ADAM17)
CD molecules [BR:
ssyn04090
]
Proteins
129468378 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reprolysin_5
Reprolysin_2
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
129468378
NCBI-ProteinID:
XP_055109825
LinkDB
All DBs
Position
18:102770661..102838652
Genome browser
AA seq
824 aa
AA seq
DB search
MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
QTSTHVETLLTFSALKRHFKLYLTSSTEHFSQNFKVVVVDGKNESEYTVKWQDFFTGHVV
GEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQS
PKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRAEPDPMKNTCKLLVVADHRFYRYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGVQIEQIRILKSPQEVKPGEKHYNM
AKSYPHEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSC
KVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLS
INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMD
SASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHVDEDGFEKD
PFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
NT seq
2475 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagtctctcctattcctgaccagcgtggttcctttcgtgctggcgccgcgacct
ccggacgacccgggcttcggcccccaccagagactcgagaagcttgattctttgctctca
gactacgatattctctctctatctaatatccagcagcattcggtaagaaaaagagatcta
cagacttcaacacatgtagaaacactactaactttttcagctttgaaaaggcattttaaa
ttatacctgacatcaagtactgaacatttttcacaaaatttcaaggtcgtggtggtggat
ggtaaaaatgaaagtgagtacactgtgaaatggcaggacttcttcactggacacgtggtt
ggtgagcctgactctagggttctagcccacataagagatgatgatgttataatcagaatc
aacacagatggggccgaatataacatagagccactttggagatttgttaatgataccaaa
gacaaaagaatgttagtttataaatctgaagatatcaagaatgtttcacgtttgcagtct
ccaaaagtatgtggttatttaaaagtggataatgaagagttgctcccaaaagggttagta
gacagagaaccacctgaagagcttgttcatcgagtgaagagaagagctgaaccagatccc
atgaagaacacgtgtaaattattggtggtagcagatcatcgcttctacagatacatgggc
agaggggaagagagtacaactacaaattacttaatagagctaattgacagagttgatgac
atctatcggaacacttcatgggataatgcgggttttaaaggctatggagtacagatagag
cagattcgcattctcaagtctccacaagaggtaaaacctggtgaaaagcactacaatatg
gcaaaaagttacccacatgaagaaaaggatgcttgggatgtgaagatgttgctagagcaa
tttagctttgatatagctgaagaagcatctaaagtttgtttggcacaccttttcacatac
caagattttgatatgggaactcttggattagcttatgttggctctcccagagcaaacagc
catggaggtgtttgtccaaaggcttattatagcccagttgggaagaaaaatatctatttg
aatagtggtttgacgagcacaaagaattatggtaaaaccatccttacaaaggaagctgac
ctggttacaactcatgaattgggacacaattttggagcagaacatgatccggatggtcta
gcagaatgtgccccgaatgaggaccagggaggaaagtatgtcatgtatcccatagctgtg
agtggcgatcacgagaacaataagatgttttcaaactgcagtaaacaatcaatctataag
accattgaaagtaaggcccaggagtgttttcaagaacgcagcaataaagtgtgtgggaac
tcgagggtggatgaaggagaagagtgtgatcctggcatcatgtatctgaacaacgacacc
tgctgcaacagcgactgcacgttgaaggaaggtgtccagtgcagtgataggaatagtcct
tgctgtaaaaactgtcagtttgagactgcccagaagaagtgccaggaggcaattaatgct
acttgcaaaggcgtgtcctactgcacaggtaatagcagtgagtgcccgcctccgggaaat
gctgaagatgacactgtttgcttggatcttggcaagtgtaaggatgggaaatgcatccct
ttctgcgagagggaacagcagctggagtcctgtgcgtgtaatgaaactgacaactcttgc
aaggtgtgctgcagggacctttctggccgctgtgtgccctacgtcgatgctgaacaaaag
aacttatttttgaggaaaggaaagccctgtacagtaggattttgtgacatgaatggcaaa
tgtgagaaacgagtacaggatgtaattgaacgattctgggatttcattgaccagctaagc
atcaatacttttggaaagtttttagcagacaacatcgttgggtctgtcctggttttctcc
ttgatattttggattcctttcagcattcttgtccattgtgtggataagaaattggataag
cagtatgaatctctgtctctgtttcaccccagtaatgttgaaatgctgagcagcatggat
tccgcatcggttcgcattatcaaaccctttcctgcgccccagactccaggccgcctgcag
cctgcccctgtgatcccttcggcgccagcagctccaaaactggaccaccagagaatggac
accatccaggaagaccctagcacagactcacatgtggacgaggatgggtttgagaaggac
cccttcccaaatagcagcacagccgccaagtcatttgaggatctcacggaccatccggtc
accagaagtgaaaaggctgcctcctttaaactgcagcgtcagaatcgtgttgatagcaaa
gaaacagagtgctaa
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