Symphalangus syndactylus (siamang): 129490748
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Entry
129490748 CDS
T10134
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn00350
Tyrosine metabolism
ssyn00790
Folate biosynthesis
ssyn01100
Metabolic pathways
ssyn04728
Dopaminergic synapse
ssyn04917
Prolactin signaling pathway
ssyn05012
Parkinson disease
ssyn05030
Cocaine addiction
ssyn05031
Amphetamine addiction
ssyn05034
Alcoholism
Module
ssyn_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
129490748 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
129490748 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
129490748 (TH)
09156 Nervous system
04728 Dopaminergic synapse
129490748 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
129490748 (TH)
09165 Substance dependence
05030 Cocaine addiction
129490748 (TH)
05031 Amphetamine addiction
129490748 (TH)
05034 Alcoholism
129490748 (TH)
Enzymes [BR:
ssyn01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
129490748 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
129490748
NCBI-ProteinID:
XP_055150518
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All DBs
Position
1:101165990..101173843
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AA seq
528 aa
AA seq
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MPTPDATTPQAKGFRRAVSELDAKQAEAIMVRGQGDPGPSLTGSPWPGTAAPAASYTPTP
RSPRFIGRRQSLIEDARKEREAAVAAAAAAAPLEPGDPLEAVAFEEKEGKAVLNLLFSLR
ATKPSALSRAVKVLETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVPRGDLAALLSGVR
QVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEI
AFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNI
PQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCC
HELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYG
AGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYAS
RIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccgacgccaccacgccacaggccaagggcttccgcagggccgtgtctgag
ctggacgccaagcaggcagaggccatcatggtaagagggcagggggacccagggcccagc
ctcacaggctctccgtggcctggaactgcagccccagctgcatcctacacccccaccccg
aggtccccgaggttcattgggcggaggcagagcctcatcgaggacgcccgcaaggagcgg
gaggcggcggtggcagcagcggctgctgcagcccccttggagcccggggaccccctggag
gccgtggcctttgaggagaaggaagggaaggccgtgctaaacctgctcttctccctgagg
gccaccaagccctcggcgctgtcccgagctgtgaaggtgttggagacgtttgaagccaaa
attcaccacctagagacccggcccgcccagaggccgcgagccgggggcccccacctggag
tacttcgtgcgcctcgaggtgccccgaggggacctggccgccctgctcagtggtgtgcgc
caggtatcagaggacgtgcgcagccccgcggggcccaaggtcccctggttcccaagaaaa
gtgtcagagctggacaagtgtcatcacctggtcaccaagtttgaccctgacctggacttg
gaccacccgggcttctcggaccaggtgtaccgccagcggaggaagctgattgctgagatc
gccttccagtacaggcatggcgacccgattccccgtgtggagtacaccgccgaggagatt
gccacctggaaggaggtctacaccacgctgaagggcctctacgccacgcacgcctgcggg
gagcacctggaggcctttgctctgctggagcgcttcagcggctaccgggaagacaatatc
ccccagctggaggacgtctcccgcttcctgaaggagcgcacgggcttccagctgcggcct
gtggccggcctgctgtccgctcgggacttcctggccagcctggccttccgcgtgttccag
tgcacccagtatatccgccacgcgtcctcgcccatgcactcccctgagccggactgctgc
cacgagctgctggggcacgtgcccatgctggcagaccgcaccttcgcgcagttctcacag
gacattggcctggcgtccctgggggcctcggatgaggaaattgagaagctgtccacgctg
tactggttcacggtggagtttgggctgtgcaagcagaatggggaggtgaaggcctacggc
gccgggctgctgtcctcctacggggagctcctgcactgcctgtctgaggagcccgagatt
cgggccttcgaccctgaagctgcggccgtgcagccctaccaagaccagacataccagtca
gtctacttcgtgtctgagagcttcagtgacgccaaggacaagctcaggagctatgcctca
cgcatccagcgccccttctccgtgaagttcgacccgtacacgctggccatcgacgtgctg
gacagcccccaggccgtgcggcgctccttggagggtgtccaggacgagctggacaccctt
gcccatgcgctgagtgccattggctag
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