Streptomyces sp. CMC78: SCMC78_30130
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Entry
SCMC78_30130 CDS
T11197
Name
(GenBank) ketosynthase chain-length factor
KO
K05552
minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
stcm Streptomyces sp. CMC78
Pathway
stcm00253
Tetracycline biosynthesis
stcm01056
Biosynthesis of type II polyketide backbone
stcm01100
Metabolic pathways
stcm01110
Biosynthesis of secondary metabolites
Module
stcm_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
stcm00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
SCMC78_30130
00253 Tetracycline biosynthesis
SCMC78_30130
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
stcm01004
]
SCMC78_30130
01008 Polyketide biosynthesis proteins [BR:
stcm01008
]
SCMC78_30130
Enzymes [BR:
stcm01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
SCMC78_30130
2.3.1.260 tetracycline polyketide synthase
SCMC78_30130
Lipid biosynthesis proteins [BR:
stcm01004
]
Polyketide synthase
Component type
SCMC78_30130
Polyketide biosynthesis proteins [BR:
stcm01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
SCMC78_30130
Nonaketide PKS
SCMC78_30130
Decaketide PKS
SCMC78_30130
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Gene cluster
GFIT
Other DBs
NCBI-ProteinID:
BFP53206
UniProt:
A0AB33KEX1
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All DBs
Position
complement(3312445..3313719)
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AA seq
424 aa
AA seq
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MTAPVTEPAARTGGTDATSTAAPVVTGIGVTAPNGFGTEAWWAAVLRGESGIRPVTRFDA
EQYPAKLAGEIRDFVPEQHVPGRLLPQTDHMTRLALAAADEALTDADIDPAALPDYAAGV
ITASSAGGFEFGQRELEALWSKGGQYVSAYQSFAWFYAVNTGQISIKNGLRGPSGVLVTE
QAGGLDAVAQARRQIRKGVQLLVTGGVDSALCPWGWAAHLAGGELTEVADPTRAYLPFSG
DASGHVAGEGGALLVLEDAAAAEARGAKTYGAVAGYAATFDPAPGSGGAPRLRAAAEQAL
KEAGLRPADVDVVFADAAGRRDADRAEAEAIAALFGPSGVPVTAPKTMTGRLAAGGAALD
LAAALLALRDQVIPPTVHVAEPAADCRIDLVTEVRRPAGGLRTALVLARGRGGFNAAMVV
RRSG
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcccccgtcaccgaaccggccgcgcgtaccggcggcacggacgccacctcgacg
gccgcgcccgtcgtcaccggaatcggcgtcaccgcaccgaacggcttcggcaccgaggcc
tggtgggccgccgtgctgcgcggcgagagcggcatccggccggtcacccgcttcgacgcc
gagcagtatccggcgaagctggccggagagatccgcgacttcgttccggagcagcacgtg
ccgggccggctgctgccccagaccgaccacatgacgaggctggcgctggccgccgccgac
gaggcgctcaccgacgccgacatcgatccggccgcgctgcccgactacgcggccggtgtg
atcacggccagctcggcgggcggtttcgagttcggccagcgcgagctggaggcgctctgg
agcaagggcggccagtacgtcagcgcgtaccagtccttcgcctggttctacgcggtcaac
accggccagatctccatcaagaacgggctgcgcgggccgagcggtgtgctcgtcaccgaa
caggccggcggcctggacgcggtggcgcaggcccgccgccagatacgcaagggcgtgcag
ctgctggtcacgggcggtgtggactcggcgctgtgcccgtggggctgggcggcgcacctg
gcgggcggtgagctgacggaggtcgccgatccgacgcgggcctacctgccgttctccggg
gacgcgtccggtcatgtggccggcgaaggcggtgcgctgctcgtcctggaggacgcggcc
gccgccgaggcgcgcggcgcgaagacgtacggagcggtcgcgggctacgcggccaccttc
gacccggcaccgggctcgggcggtgcgccgcggctgcgggccgccgccgaacaggcgctg
aaggaggccggtctgcgtccggccgacgtggacgtggtcttcgccgacgcggccggacgc
agggacgccgaccgggcggaggccgaggccatcgccgcactgttcggtccgtccggagtg
ccggtgacggctccgaagaccatgacgggccgactcgccgccggtggcgcggcgctggac
ctggcggcagcgctgctggcactgcgcgaccaggtgatcccgccgaccgtgcatgtggcc
gaaccggccgctgactgccggatcgacctggtcaccgaggtccgcaggccggccggcgga
ctccgcaccgcactggtgctggcccgcggtcgcggcggtttcaacgcggccatggtggta
cgccggtccggctga
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