KEGG   Streptomyces sp. CNQ-509: AA958_30260
Entry
AA958_30260       CDS       T03968                                 
Name
(GenBank) beta-ketoacyl synthase
  KO
K05552  minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
strc  Streptomyces sp. CNQ-509
Pathway
strc00253  Tetracycline biosynthesis
strc01056  Biosynthesis of type II polyketide backbone
strc01100  Metabolic pathways
strc01110  Biosynthesis of secondary metabolites
Module
strc_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:strc00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    AA958_30260
   00253 Tetracycline biosynthesis
    AA958_30260
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:strc01004]
    AA958_30260
   01008 Polyketide biosynthesis proteins [BR:strc01008]
    AA958_30260
Enzymes [BR:strc01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     AA958_30260
    2.3.1.260  tetracycline polyketide synthase
     AA958_30260
Lipid biosynthesis proteins [BR:strc01004]
 Polyketide synthase
  Component type
   AA958_30260
Polyketide biosynthesis proteins [BR:strc01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     AA958_30260
    Nonaketide PKS
     AA958_30260
    Decaketide PKS
     AA958_30260
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C
Other DBs
NCBI-ProteinID: AKH85792
UniProt: A0A0F7NGB5
LinkDB
Position
7093862..7095100
AA seq 412 aa
MTAVAVTGLGIAAPNGLGTADYWAATRGGKSGIGRITRFDPSGYPARLAGEIPGFVDADH
LPSRLLPQTDRVTRLALTAADWALADAGVDTGAFDPLDMGVITASHAGGFEFGQYELQSL
WSKGSQYVSAYQSFAWFYAVNSGQISIRHGMKGPSGVVVTDEAGGLDALAQARRQIRKGT
PLVVSGAVDASLCPWGWVAQLAAGRMSERDEPTRAYVPFDRDATGYVPGEGGAILVLEDA
AAARARGARSYGEIAGYGATLEPGPEAGPGHADRGALRRSIEIALADAGLGTGDVDVVFA
DGAGVPEEDAAEAGTLCEVFGPRAVPVTVPKSMTGRLYSGAASLDVAAALLAMRDGVIPP
TVHVDPCPEYDLDLVLHQARPAAALRHALVLARGHGGFNAAMVLRAHPTTTG
NT seq 1239 nt   +upstreamnt  +downstreamnt
atgaccgcggtcgcggtcaccggcctgggcatcgccgcgcccaacggcctgggcaccgcc
gactactgggcggccacccgcggcggcaagagcggcatcggccgcatcacccggttcgac
ccgtccggctatccggcgcggcttgcgggagagatccccggcttcgtcgacgccgaccac
ctgcccagcaggctgctgccgcagacggaccgcgtcacgcggctcgcgctgacggcggcc
gactgggcgctggccgacgcgggcgtcgacaccggggcgttcgacccgctggacatgggc
gtgatcaccgcgagccacgcgggcggcttcgagttcggccagtacgagctgcagagcctg
tggtccaagggcagccagtacgtgtccgcgtaccagtccttcgcctggttctacgcggtc
aacagcggccagatctccatccggcacggcatgaaggggccgagcggcgtcgtcgtcacc
gacgaggccggcggtctcgacgcgctggcgcaggcccgcaggcagatccgcaagggcacg
cccctggtggtctccggcgccgtcgacgcctcgctgtgcccgtggggctgggtggcgcag
ttggccgccgggcggatgagcgagcgcgacgagccgacgcgcgcgtacgtgccgttcgac
cgcgacgccaccggctacgtgccgggggagggcggcgcgatcctcgttctggaggacgcg
gccgccgcccgcgcccgcggcgcccggagctacggggagatcgccggctacggcgccacc
ctggaaccgggccccgaggccggccccgggcacgcagaccggggggcgctgcgccggtcg
atcgagatcgccctcgccgacgccggtctcggcaccggcgacgtcgacgtcgtcttcgcc
gacggcgcgggcgtgcccgaggaggacgcggccgaggccgggacgctgtgcgaggtcttc
gggccgcgtgcggtgccggtcaccgtgcccaagtcgatgaccggccggctctactccggc
gccgcgtcgctggacgtggcggcagcgctgctggccatgcgcgacggcgtcatcccgccc
accgtgcacgtcgacccctgccccgagtacgacctggacctcgtgctgcaccaggccagg
ccggccgcggcgctgcggcacgcgctcgtactggcccgcggccacggcggcttcaacgcc
gccatggtgctgcgcgcccacccgaccaccaccggctga

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