KEGG   Streptomyces sp. 4F: ASR50_01170
Entry
ASR50_01170       CDS       T04265                                 
Name
(GenBank) beta-ketoacyl synthase
  KO
K05552  minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
strf  Streptomyces sp. 4F
Pathway
strf00253  Tetracycline biosynthesis
strf01056  Biosynthesis of type II polyketide backbone
strf01100  Metabolic pathways
strf01110  Biosynthesis of secondary metabolites
Module
strf_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:strf00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    ASR50_01170
   00253 Tetracycline biosynthesis
    ASR50_01170
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:strf01004]
    ASR50_01170
   01008 Polyketide biosynthesis proteins [BR:strf01008]
    ASR50_01170
Enzymes [BR:strf01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     ASR50_01170
    2.3.1.260  tetracycline polyketide synthase
     ASR50_01170
Lipid biosynthesis proteins [BR:strf01004]
 Polyketide synthase
  Component type
   ASR50_01170
Polyketide biosynthesis proteins [BR:strf01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     ASR50_01170
    Nonaketide PKS
     ASR50_01170
    Decaketide PKS
     ASR50_01170
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C
Other DBs
NCBI-ProteinID: ALV48166
LinkDB
Position
complement(303099..304316)
AA seq 405 aa
MTTAVVTGLGITAPNGLGTEDYWKATLAGESGLGPVTRFDASPYPSRVAGEVADYIAEDH
IPSRLMPQTDHMTRLALTAADWALADGGIDTAELPQYGIGVVTAASGGAVEFGQRELQNL
WSKGKEYVSAYQSFAWFYAVNTGQISIRHKLRGPSGVLLTEQAGGIDSLGHARRHIRKGF
PAVISGGVDAAICPWGWVPQIASGLMSTVDDPARAYLPFSAEAAGYVPGEGGAILLVEEA
ASARARGAATVYGQIAGYAATLDPAPGSGRPPGLRKAAENALADAGVDAADIDVVFADAA
GVPDLDRAEAQALTGLFGAHGVPVTAPKTMTGRLLAGGAALDVATALLALRDGVIPPTVN
VGAAAADHRLDLVTEPREATLRTALVLARGHLGFNAALVVRRWAA
NT seq 1218 nt   +upstreamnt  +downstreamnt
atgaccaccgcagtggtgaccggcctgggcatcaccgcccccaacggcctgggaaccgag
gactactggaaggcgacgctggccggcgagtccggcctcggaccggtcacccgcttcgac
gcctccccgtacccctcccgtgtcgccggggaggtggccgactacatcgccgaggaccac
atccccagccggctcatgccgcagaccgaccacatgacgcgcctcgcgctgaccgccgcc
gactgggcgctcgccgacggcggcatcgacaccgccgaactgccgcagtacggcatcggc
gtggtgaccgccgcgtccggcggggccgtcgagttcggccagcgggaactgcagaacctg
tggagcaagggcaaggagtacgtcagcgcgtaccagtccttcgcctggttctacgcggtc
aacaccggccagatctccatccggcacaaactgcgcggccccagcggcgtcctgctcacc
gaacaggccggcggcatcgactcgctcggccacgcccgccgccatatccgcaagggcttc
ccggccgtcatctccggcggcgtcgacgcggccatctgcccctggggctgggtgccgcag
atcgcctccggactgatgagcaccgtcgacgatccggcccgcgcctatctgccgttctcc
gccgaggccgccgggtacgtccccggcgagggcggggcgatcctcctcgtcgaggaggcc
gcgtcggcccgcgcccgcggtgccgccacggtctacggtcagatcgccgggtacgcggcc
accctcgacccggcccccggatcgggccgcccgcccggcctgcgcaaggccgccgagaac
gccctggccgacgccggcgtcgacgccgccgacatcgacgtggtcttcgccgacgccgcc
ggcgtaccggacctggaccgggccgaggcccaggcactgaccggtctgttcggcgcgcac
ggcgtccccgtcaccgcacccaagacgatgaccggccgcctgctcgccggcggcgccgcg
ctcgacgtggccaccgccctgctcgccctgcgcgacggcgtcatcccgcccaccgtcaac
gtcggtgccgccgcggccgatcaccgcctcgacctggtcaccgaaccgcgcgaggccacc
ctgcgcaccgcgctcgtcctcgcccgcggccacctcggcttcaacgcggcgctcgtcgtg
cgccgctgggccgcctga

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