KEGG   Streptomyces sp. PAMC 26508: F750_1306
Entry
F750_1306         CDS       T02619                                 
Symbol
whiE-CLF
Name
(GenBank) polyketide chain length factor WhiE-CLF
  KO
K05552  minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
strp  Streptomyces sp. PAMC 26508
Pathway
strp00253  Tetracycline biosynthesis
strp01056  Biosynthesis of type II polyketide backbone
strp01100  Metabolic pathways
strp01110  Biosynthesis of secondary metabolites
Module
strp_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:strp00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    F750_1306 (whiE-CLF)
   00253 Tetracycline biosynthesis
    F750_1306 (whiE-CLF)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:strp01004]
    F750_1306 (whiE-CLF)
   01008 Polyketide biosynthesis proteins [BR:strp01008]
    F750_1306 (whiE-CLF)
Enzymes [BR:strp01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     F750_1306 (whiE-CLF)
    2.3.1.260  tetracycline polyketide synthase
     F750_1306 (whiE-CLF)
Lipid biosynthesis proteins [BR:strp01004]
 Polyketide synthase
  Component type
   F750_1306 (whiE-CLF)
Polyketide biosynthesis proteins [BR:strp01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     F750_1306 (whiE-CLF)
    Nonaketide PKS
     F750_1306 (whiE-CLF)
    Decaketide PKS
     F750_1306 (whiE-CLF)
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C
Other DBs
NCBI-ProteinID: AGJ53814
LinkDB
Position
1324053..1325321
AA seq 422 aa
MTAPAPASTAPGTRRGTALVTGLDVRAANGDGTEEFWRSLLEGRGGIGPITRFDASGYPS
RLAGEIARDPGEDLPGRLLPQTDRVTQLALACAAEVLRDSGLDPAGAPEYGIGVVTANAA
GGFEFGQRELENLWAKGPLYVSAYQSFAWFYAVNTGQISIRHGLRGPSGVLVTGQSGGLD
AVGHARRMLRKGTPAVLTGAMESALCPWGHVAELTGGRLSTADRSEDACLPFGERAAGHV
VAEGGALLMLEDAASAHARGGIRPYGEVAGYAACFDPPPGSGRPTGPARAARAALADAGV
EPADIGAVFAEGAAVPDLDAQEAGAIAEVFGPDAVPVTAITSRTGRPGAGASALDLAAAL
LAVRDGLIPPTADVGRVPAAYRIDLVTGRPRPMAGDAALVLARGYGGFNSAVVVRRCGPT
PR
NT seq 1269 nt   +upstreamnt  +downstreamnt
atgaccgcccccgcacccgcgtccacggcacccggaacccggcggggcacggccctggtc
accggcctcgacgtgcgggcggccaacggggacggcaccgaggagttctggcggagcctg
ctggagggacgcggcggcatcggcccgatcacccgcttcgacgcctccggctacccgagc
cggctggccggcgagatcgcacgcgaccccggcgaggacctgcccggccgcctgctgccc
cagaccgaccgcgtcacacagctcgcgctggcctgtgccgccgaggtgctgcgggactcg
ggcctggacccggccggggcgcctgagtacgggatcggggtggtcaccgccaatgccgcc
ggcgggttcgagttcggtcagcgggagctggagaacctgtgggcgaaaggccccctgtac
gtcagcgcctaccagtcgttcgcctggttctacgccgtcaacaccggccagatctccatc
cggcacggcctgcgcggccccagcggcgtcctggtcaccggccagtccggcggcctggac
gcggtgggccacgcgcgccgcatgctgcgcaagggcaccccggcggtgctcaccggggcg
atggagtcggcgctgtgcccctgggggcacgtggcggagctgaccggcggccggctgagt
accgccgaccggtccgaggacgcctgcctgcctttcggggagcgcgccgccggtcatgtc
gtcgcggagggcggcgcgctgctgatgctggaggacgcggcctcggctcacgccagagga
ggcatccgcccgtacggcgaggtggcgggttacgcggcctgcttcgaccctcccccgggc
tcggggcggcccacgggcccggcgcgggccgcgcgcgcggcgctggccgacgcgggagtg
gaaccggcggacatcggcgcggtgttcgccgagggagccgcggttccggatctcgacgcg
caggaggccggggcgatcgccgaggtcttcgggccggacgccgtgccggtcaccgcgatc
acctcccgcaccgggcgcccgggggccggcgcctccgcgctcgacctcgcggcggcgctg
ctcgccgtccgtgacgggctgatccccccgaccgccgacgtcggccgggtcccggcggcg
taccggatcgacctcgtgaccggccggccccggccgatggccggcgacgcggcactggtg
ctggcgcgtgggtacggcggcttcaacagcgccgtggtcgtgcgccggtgcggaccgaca
ccccgatga

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