Tachyglossus aculeatus (Australian echidna): 119943736
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Entry
119943736 CDS
T10703
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu00350
Tyrosine metabolism
tacu00790
Folate biosynthesis
tacu01100
Metabolic pathways
tacu04728
Dopaminergic synapse
tacu04917
Prolactin signaling pathway
tacu05012
Parkinson disease
tacu05030
Cocaine addiction
tacu05031
Amphetamine addiction
tacu05034
Alcoholism
Module
tacu_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
119943736 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
119943736 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
119943736 (TH)
09156 Nervous system
04728 Dopaminergic synapse
119943736 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
119943736 (TH)
09165 Substance dependence
05030 Cocaine addiction
119943736 (TH)
05031 Amphetamine addiction
119943736 (TH)
05034 Alcoholism
119943736 (TH)
Enzymes [BR:
tacu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
119943736 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
119943736
NCBI-ProteinID:
XP_038620809
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All DBs
Position
22:complement(56681483..56731757)
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AA seq
493 aa
AA seq
DB search
MPTSKTPSSSSKGFRRAVSELDSKQAEAVMSPRFIGRRRSLIEDARKEREAAEAAAASEA
GDGAETIVFEERDGKAVANLFFALKGTKTASLSRVMKVFETFEAKIHHLETRANRKARDG
PSGLEFFIRCEVHSADLSTLVSSIRRVTDDVRSPKEDKFHWFPRKISELDRCHHLVTKFD
PDLDLDHPGFSDQAYRQRRKMVAEIAFQYKHGDPIPRVDYTAEEIATWREVYRTLKSLYP
THACSEHLEALDLLEKFSGYSENNIPQLEDVSRFLKDRTGFQLRPVAGLLSARDFLSSLA
FRVFQCTQYIRHSSSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGATDEEIE
KLSTLYWFTVEFGLCKQNGVIKAYGAGLLSSYGELLHALSDEPEIREFDPETVSVQPYQD
QTYQPVYFVSESFSDAKDKLRNYASGIRRPFSVKYDPHTQAVEVLDSPQKIRRFLDGLRE
ELHSLAQALNAFS
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcccacttcgaagaccccctcctcatcctccaaaggattccgccgggccgtgtccgaa
ctcgactccaagcaagccgaggccgtcatgtctccacggttcatcggacgtcgccgaagc
ctgatcgaagatgcgaggaaggagcgagaggcggcagaagctgcggcggcttcggaggcc
ggagatggggcagagaccatcgtcttcgaggagagggatggcaaggctgtggccaacctc
ttctttgcgctcaaggggaccaagacggcatctttgtctcgtgtcatgaaagtatttgag
acgttcgaagccaaaatccatcacttggagacgagggccaacagaaaggctcgggatggg
ccttcgggcctggagttcttcatccgctgtgaagtccacagcgctgacctcagcacactg
gtcagttccatccggagggtcacggacgacgtcaggagcccgaaagaagacaagttccac
tggtttccaagaaagatctccgaactggaccggtgccaccacctcgtcaccaagtttgat
cctgacctggatttggaccacccgggcttttcggaccaggcctaccggcagcggaggaag
atggtagccgagatcgccttccagtacaaacacggcgaccccatcccgcgagtggactac
acggccgaggagatcgccacgtggagggaggtgtacaggacgctgaagagcttgtatccc
acccacgcctgctcggagcacctggaggccttggatctgctggagaagttcagcggctac
agcgagaacaacatcccgcagctcgaagacgtgtcccgcttcctcaaagacagaactggg
ttccagctgcggccagtggccggcctgctgtccgcacgggacttcctgtccagcctggcc
ttcagagttttccaatgcactcaatacattcgccattcctcctcgcccatgcactccccg
gaaccagattgctgccacgaacttctgggtcatgtacctatgctggccgacaggacattc
gctcagttctcccaggacattggactcgcttcccttggggccacggatgaagagatagag
aaattgtccacgctctattggttcacggtggaatttgggctctgcaaacagaatggcgtc
atcaaggcctacggggctgggcttctgtcatcctacggagagcttctgcatgctctgtcc
gacgagccggagatcagggaattcgaccccgagaccgtgtccgtccagccataccaggac
cagacgtaccagcccgtgtacttcgtgtctgagagcttcagcgacgccaaagacaagctc
aggaactacgcatccgggatccgacggccattctccgtgaaatatgacccccacacacag
gccgtggaagtgcttgacagcccgcagaagattcgccgcttcctggatggcctccgagag
gagctgcacagcctggcccaggccctcaacgccttcagctag
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