KEGG   Tachyglossus aculeatus (Australian echidna): 119947396
Entry
119947396         CDS       T10703                                 
Name
(RefSeq) steroid 21-hydroxylase
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
tacu  Tachyglossus aculeatus (Australian echidna)
Pathway
tacu00140  Steroid hormone biosynthesis
tacu01100  Metabolic pathways
tacu04925  Aldosterone synthesis and secretion
tacu04927  Cortisol synthesis and secretion
tacu04934  Cushing syndrome
Module
tacu_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:tacu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    119947396
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    119947396
   04927 Cortisol synthesis and secretion
    119947396
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    119947396
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:tacu00199]
    119947396
Enzymes [BR:tacu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     119947396
Cytochrome P450 [BR:tacu00199]
 Cytochrome P450, animal type
  CYP21 family
   119947396
SSDB
Motif
Pfam: p450 TP_0927
Other DBs
NCBI-GeneID: 119947396
NCBI-ProteinID: XP_038625003
LinkDB
Position
Y4:1913834..1920047
AA seq 491 aa
MLLLALLLLGALAALWVWGAPLFHRSKLHLPPRVPGFLHQLRPNLPIHLLHLAHTHGPLY
RIHFGNQDVVILNSRQLIWEAMVKNWLNFAGRPLMKSSQLVSMGGKDLSLGNYSPAWKDL
KKLTVSALQLEMRNKMEPMVWRLAHEQFEGFRAQAGSTVDLFREFSKLTNRIICTITFGD
LEESTLQDVQDCTSELVSLWASSSIRILDIFPFLRFIPYPALRRMKTLLKKRDRFIREQM
RRHRETQVSGVVRDMTDYMLRELREKSGAWDVSEEHMHMALLDLVIGGTGTTAAVLNWVV
LFLLHYPEVQKRLQDELDLELGPASSASSASLLPYKDRARLPLLNATITEVLRLRPVVAL
GLPHLTLRDTSLGGFDIPRNTIVIPNLYGAHHDAAVWEQPFAFRPDRFLKAESSQLPLPF
GCGARICVGEGLARVEIFLILVQLLQRFTLSPAPASAAALPSLTPDFGGVTKSQPFRVHL
LPRGGGGRAAT
NT seq 1476 nt   +upstreamnt  +downstreamnt
atgctgctgttggccctgcttctgctgggggctctggccgccctctgggtgtggggggct
ccgctcttccaccggtcgaagctccacctgcccccgcgtgtccccggtttcctgcaccag
ctccggcccaacctgcccatccacctgctccaccttgcccatacacacgggcccctctac
cgcatccactttgggaaccaggatgtcgtgattctgaactccaggcaactgatttgggaa
gccatggtcaagaactggctgaactttgcggggagaccactgatgaaatcctcccagctg
gtgtccatgggagggaaggacctgtctctgggcaactactctccagcctggaaagacctg
aagaagctcaccgtctccgctctccagctcgagatgcgcaacaagatggagcccatggtg
tggcggctggcccacgagcagttcgagggcttccgggcccaggccggcagcaccgtggac
ttattccgggaattctccaagctcaccaaccgcatcatctgcaccatcaccttcggggac
ttggaggagtccaccttgcaggacgtgcaggactgcacctcggaactggtatctctgtgg
gcctcctcgtccatccgcatcctggacatcttccccttcctccggttcatcccctacccg
gccctgagacgcatgaaaacgttgctgaagaaacgggaccggttcatcagagagcagatg
cggaggcacagggagacgcaggtgtccggcgtggtgcgggacatgacggattacatgctg
cgggagctgcgggagaagagcggcgcgtgggacgtctccgaagagcacatgcacatggcc
ctcctcgacttggtgatcgggggcacggggaccacggcggccgtgctgaactgggtggtc
ctcttcttgctccactaccccgaggtccagaagaggctgcaggatgagctggacttggag
ttgggcccggcctcctcggcttcctcggcctccctgctgccctacaaggaccgggcgcgg
ctgcccctgctcaacgccaccatcaccgaggtgctgcgcctccggcccgtcgtcgccctg
ggcctcccgcacctcaccctcagagataccagcctcggcggcttcgacatcccccgcaac
acgatcgtgatccccaacctgtacggagcccaccacgacgccgccgtctgggagcagccc
ttcgccttccgaccggatcgcttcctgaaggcggagtcgtcccagctgcccctgccgttt
ggctgcggggcccggatctgcgtgggcgagggcctggcccgcgtggagatcttcctcatt
ctggtccagctgctccagcgcttcacgctcagcccggccccggccagcgccgccgccctg
ccctccctcacccccgacttcggaggcgtcacgaagagccagcccttccgcgtgcacctg
ctgcccaggggagggggcggccgggctgccacctaa

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