KEGG   Thermomonospora curvata: Tcur_2772
Entry
Tcur_2772         CDS       T01127                                 
Name
(GenBank) Beta-ketoacyl synthase
  KO
K05552  minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
tcu  Thermomonospora curvata
Pathway
tcu00253  Tetracycline biosynthesis
tcu01056  Biosynthesis of type II polyketide backbone
tcu01100  Metabolic pathways
tcu01110  Biosynthesis of secondary metabolites
Module
tcu_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:tcu00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    Tcur_2772
   00253 Tetracycline biosynthesis
    Tcur_2772
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:tcu01004]
    Tcur_2772
   01008 Polyketide biosynthesis proteins [BR:tcu01008]
    Tcur_2772
Enzymes [BR:tcu01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     Tcur_2772
    2.3.1.260  tetracycline polyketide synthase
     Tcur_2772
Lipid biosynthesis proteins [BR:tcu01004]
 Polyketide synthase
  Component type
   Tcur_2772
Polyketide biosynthesis proteins [BR:tcu01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     Tcur_2772
    Nonaketide PKS
     Tcur_2772
    Decaketide PKS
     Tcur_2772
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C
Other DBs
NCBI-ProteinID: ACY98318
UniProt: D1A6R4
LinkDB
Position
complement(3228917..3230134)
AA seq 405 aa
MTQRAVVTGIGIAAPNGLGPTAYWRAVMNGVSGLRTVTRFDISKYRSKVGGEVPDFDAER
HLQSRLLPQTDHMTRLALVAADWALRQAGLKEGDVPSNRMSVVTAATGGGYEFGQRELAK
LHGQGPDHVSAYQSFAWFYAVNAGQISIRHGMRGAGSVVVSEQAGGLDAIGHGRRQLADG
SRLVLTGGVDSALCPWAWVAHQATGAMSRCPDPARAYLPFDERANGYVPGEGGAIMVLEA
AELAEKRPGTRIYGEVAGYAATFDSRRPGRPSGLRRVIELALGDAGMDPRDIDVVFADAA
GDLALDRAEAEAIAAVFGPRGVPVTAPKTMTGRLFAGGGPLDVASALLAMYWGAIPPTVN
VREAVPDYELDLVLGRPRYEPVRAALVLARGHGGFNSAIVVREYR
NT seq 1218 nt   +upstreamnt  +downstreamnt
atgacccagcgggcagtggtaaccgggatcggcatagcggcgcccaacggtcttgggccg
accgcatactggcgcgccgtgatgaacggggtgtccggcctccgcacggtcacccgtttc
gacatctccaaataccgcagcaaggtcggcggtgaggtgcccgacttcgacgccgagcgg
cacctgcagagcaggctgctgccgcaaaccgatcacatgacccgcctggccctggtggcg
gccgactgggcgctgcggcaggccggcctcaaggagggggacgtgccctccaaccggatg
agcgtggtcaccgcggcgacgggcggcgggtatgagttcggccagcgggaactggccaag
ctgcacggccagggacccgaccacgtcagcgcctaccagtcgttcgcctggttctatgcg
gtcaacgccggccagatctcgatccggcacggcatgcgcggcgccggctcggtggtggtc
agcgagcaggccggcgggctggacgccatcgggcacggccgtcggcagttggcggacggc
tcccggctcgtcctcaccggcggcgttgacagcgcgctgtgcccctgggcgtgggtggcg
catcaggccaccggcgcgatgagccgctgccccgacccggcccgggcgtacctgcccttc
gatgagcgggccaacggctatgtgcccggggagggcggggcgatcatggttctggaggcc
gccgaactggccgagaaacgcccgggcaccaggatctacggagaggtcgccggttacgcg
gcgaccttcgactcccgtcgcccgggccggccctcgggtctgcgccgggtcatcgagctc
gccctcggcgacgccgggatggacccccgcgacatcgacgtggtcttcgccgacgcggcc
ggagacctcgccctggaccgggcggaggcggaggcgatcgccgcggtgttcgggccgcgc
ggcgtgccggtcaccgcgcccaagaccatgaccggacggctgttcgccggcggcggcccg
ctggacgtcgcctcggcgctgctggcgatgtactggggcgcgatcccgcccaccgtcaac
gtccgcgaggcggtccccgactacgaactggacctggtgctcgggcggccccgctatgaa
ccggtgcgggcggcgctggtgctggccagggggcacggcggtttcaactcggcgatcgtg
gtgcgcgaataccgctga

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