Trachypithecus francoisi (Francois's langur): 117081144
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Entry
117081144 CDS
T07225
Symbol
TH
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn00350
Tyrosine metabolism
tfn00790
Folate biosynthesis
tfn01100
Metabolic pathways
tfn04728
Dopaminergic synapse
tfn04917
Prolactin signaling pathway
tfn05012
Parkinson disease
tfn05030
Cocaine addiction
tfn05031
Amphetamine addiction
tfn05034
Alcoholism
Module
tfn_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
117081144 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
117081144 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
117081144 (TH)
09156 Nervous system
04728 Dopaminergic synapse
117081144 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
117081144 (TH)
09165 Substance dependence
05030 Cocaine addiction
117081144 (TH)
05031 Amphetamine addiction
117081144 (TH)
05034 Alcoholism
117081144 (TH)
Enzymes [BR:
tfn01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
117081144 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
117081144
NCBI-ProteinID:
XP_033062712
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All DBs
Position
Unknown
AA seq
497 aa
AA seq
DB search
MPTPDATTPQAKGFXRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAA
PSEPGDPLEAVAFEEKEGKAVLNLLFSLRATKPSALSRAVKVFETFEAKIHHLETRPAQR
LRAGGPHLEYFVRLEVPRGDLAALLSGVRQVSEDVRSPAEPKVPWFPRKVSELDKCHHLV
TKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLK
GLYATHACAEHLEAFTLLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFL
ASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASD
EEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQ
PYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRHSLE
GVQDELDTLAHALSAIG
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccgacgccaccacaccacaggccaagggcttcngcagggctgtgtctgag
ctggatgccaagcaggcagaggccatcatgtccccgcggttcattgggcgacggcagagc
ctcatcgaggatgcccgcaaggagcgggaggcagcggtggcagcagcagctgctgcagcc
ccctcggagcccggggaccccctggaggccgtggcctttgaggaaaaggaggggaaggcc
gtgctaaacctgctcttctccctgagggccaccaagccctcagcgctgtcccgagctgtg
aaggtgtttgagacgtttgaagccaaaatccaccacctagagacccggcccgcccagagg
ctgcgagccgggggcccccacctggagtactttgtgcgcctcgaggtgccccgaggggac
ctggccgccctgctcagtggcgtgcgccaggtgtcagaggacgtgcgcagccccgcggag
cccaaggtcccctggttcccaagaaaagtgtcagagctggacaagtgtcatcacctggtc
accaagtttgaccctgacctggacttggaccacccgggcttctcggaccaagtgtaccgc
cagcgcaggaagctgattgctgagattgccttccagtacaggcacggcgacccgattccc
cgtgtggagtacaccgccgaggagattgccacctggaaggaggtctacaccactctgaaa
ggcctctacgccacgcacgcctgcgcggagcacctggaggcctttaccctgctggaacgc
ttcagcggctaccgggaagacaacatcccccagctggaggatgtctcccgcttcctgaag
gagcgcacgggcttccagctgcggcctgtggccggcctgctgtccgcccgggacttcctg
gccagcctggccttccgcgtgttccagtgcacccagtatatccggcacgcgtcctcgccc
atgcactcccccgagccggactgctgccacgagctgctggggcacgtgcccatgctggcc
gaccgcaccttcgcgcagttctcccaggacattggcctggcatccctgggggcttcggat
gaggaaattgagaagctgtccacgctgtactggttcaccgtggagtttgggctgtgcaaa
cagaacggggaggtgaaggcctatggcgccgggctgctgtcctcctatggggagctcctg
cactgcctgtctgaggagcccgagattcgagccttcgaccctgaagcagcagccgtgcag
ccctaccaagaccagacgtaccagtcagtctacttcgtgtctgagagcttcagcgacgcc
aaggataagctcaggagctatgcctcacgcatccagcgccccttctccgtgaagttcgac
ccgtacaccctggccatcgacgtgctggacagcccccaggccgtgcggcactccctggag
ggtgtgcaggatgagctggacaccctggcccatgcgctgagtgccattggctag
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