Thermobifida fusca: Tfu_1219
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Entry
Tfu_1219 CDS
T00265
Name
(GenBank) actinorhodin polyketide beta-ketoacyl synthase beta subunit / 3-oxoacyl-ACP synthase II
KO
K05552
minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
tfu
Thermobifida fusca
Pathway
tfu00253
Tetracycline biosynthesis
tfu01056
Biosynthesis of type II polyketide backbone
tfu01100
Metabolic pathways
tfu01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
tfu00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
Tfu_1219
00253 Tetracycline biosynthesis
Tfu_1219
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
tfu01004
]
Tfu_1219
01008 Polyketide biosynthesis proteins [BR:
tfu01008
]
Tfu_1219
Enzymes [BR:
tfu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
Tfu_1219
2.3.1.260 tetracycline polyketide synthase
Tfu_1219
Lipid biosynthesis proteins [BR:
tfu01004
]
Polyketide synthase
Component type
Tfu_1219
Polyketide biosynthesis proteins [BR:
tfu01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
Tfu_1219
Nonaketide PKS
Tfu_1219
Decaketide PKS
Tfu_1219
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Motif
Other DBs
NCBI-ProteinID:
AAZ55257
UniProt:
Q47QL2
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All DBs
Position
1422467..1423675
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AA seq
402 aa
AA seq
DB search
MTTTVVTGLGVIAPTGLGVDDYWKATLEGRNGIAPITKFDASGYPSSLAGQVVGFHAADH
LPGRLLPQTDHMTRMALAAAQWAWDDAGLDPAQLPEFSAGVVTASSSGGYEFGERELRNL
WAKGASYVSAYQSFAWFYAVNTGQISIRHQMRGPTGVLVSDQAGGADAIAHARRQIRKGA
RVMLAGGVDSSLCSWGWIAHLASGRVSTADDPRRAYLPFSADARGHVPGEGGALLVLEEE
TAARARGARIYGVVAGHAATLDPPPGSGRPSTLEAALRGALADADVHPDEVDVVFCDGAA
IPELDRIEAAAINAVFGEGAVPVTVPKTMTGRLFSGAVALDAAAALLSIRDGVIPPTINA
TAAPDLGLDLVTETPRSLPVRIALIVARGIGGFNSALVLRAA
NT seq
1209 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccacagtggtgaccggactcggagtgatcgcccccaccggcctcggcgtcgac
gactactggaaggccaccctggaaggccgcaacggcatcgcgccgatcaccaagttcgac
gcgagcggataccccagttcgctcgcggggcaagtcgtcggattccacgccgccgaccac
ctgcccggccgtctcctgccgcagaccgaccacatgaccagaatggcgctcgccgccgcc
cagtgggcatgggacgacgcgggcctggaccccgcccagttgccggagttctccgccgga
gtggtgacggccagctcctcaggcggctacgagttcggtgaacgggaactccgcaacctg
tgggccaaaggcgccagctacgtcagcgcctaccagtcgttcgcctggttctacgcggtc
aacaccggtcagatctccatccgccaccagatgcgcggccccacgggagtcctcgtctcc
gaccaggccgggggagcagacgcgatcgcccacgcccgccggcagatccgcaaaggcgcc
cgtgtcatgctcgccgggggtgtcgacagctccctgtgctcctgggggtggatcgcccac
ctcgcttcgggacgggtcagcaccgcggacgacccccgccgcgcctacctcccgttctct
gccgacgcccgagggcacgtgcccggggaaggcggagcactgctggtactcgaagaggaa
accgcagcccgggcccgcggcgcccgcatctacggggttgtcgcgggccacgccgccacg
ctcgaccctccgcccggaagcggccgtcccagcaccctggaagcggccctgcgcggcgcc
ctcgccgacgcggacgtccaccccgacgaagtcgacgtggtcttctgcgacggcgccgcc
atcccggaactcgaccggatcgaagccgcagccatcaacgccgtcttcggggaaggggcc
gtccccgtcaccgttcccaagaccatgaccggacgcctcttctccggggcggtcgcgctc
gacgctgccgcagccctcctcagcatccgcgacggcgtcatcccacccaccatcaacgcc
accgccgcccccgacctcgggctggacctggtcaccgaaacccctcggagcctgcccgtc
cgcatcgccctgatcgtcgcccgcggaatcggcggcttcaactccgccctcgtcctccgc
gcggcctaa
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