KEGG   Talpa occidentalis (Iberian mole): 119257947
Entry
119257947         CDS       T07495                                 
Symbol
CASP3
Name
(RefSeq) caspase-3
  KO
K02187  caspase 3 [EC:3.4.22.56]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod01524  Platinum drug resistance
tod04010  MAPK signaling pathway
tod04115  p53 signaling pathway
tod04148  Efferocytosis
tod04210  Apoptosis
tod04215  Apoptosis - multiple species
tod04623  Cytosolic DNA-sensing pathway
tod04650  Natural killer cell mediated cytotoxicity
tod04657  IL-17 signaling pathway
tod04668  TNF signaling pathway
tod04726  Serotonergic synapse
tod04932  Non-alcoholic fatty liver disease
tod04933  AGE-RAGE signaling pathway in diabetic complications
tod04936  Alcoholic liver disease
tod05010  Alzheimer disease
tod05012  Parkinson disease
tod05014  Amyotrophic lateral sclerosis
tod05016  Huntington disease
tod05020  Prion disease
tod05022  Pathways of neurodegeneration - multiple diseases
tod05132  Salmonella infection
tod05133  Pertussis
tod05134  Legionellosis
tod05145  Toxoplasmosis
tod05146  Amoebiasis
tod05152  Tuberculosis
tod05160  Hepatitis C
tod05161  Hepatitis B
tod05162  Measles
tod05163  Human cytomegalovirus infection
tod05164  Influenza A
tod05165  Human papillomavirus infection
tod05167  Kaposi sarcoma-associated herpesvirus infection
tod05168  Herpes simplex virus 1 infection
tod05169  Epstein-Barr virus infection
tod05170  Human immunodeficiency virus 1 infection
tod05200  Pathways in cancer
tod05203  Viral carcinogenesis
tod05205  Proteoglycans in cancer
tod05206  MicroRNAs in cancer
tod05210  Colorectal cancer
tod05222  Small cell lung cancer
tod05416  Viral myocarditis
tod05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119257947 (CASP3)
   04668 TNF signaling pathway
    119257947 (CASP3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    119257947 (CASP3)
  09143 Cell growth and death
   04210 Apoptosis
    119257947 (CASP3)
   04215 Apoptosis - multiple species
    119257947 (CASP3)
   04115 p53 signaling pathway
    119257947 (CASP3)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    119257947 (CASP3)
   04650 Natural killer cell mediated cytotoxicity
    119257947 (CASP3)
   04657 IL-17 signaling pathway
    119257947 (CASP3)
  09156 Nervous system
   04726 Serotonergic synapse
    119257947 (CASP3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119257947 (CASP3)
   05206 MicroRNAs in cancer
    119257947 (CASP3)
   05205 Proteoglycans in cancer
    119257947 (CASP3)
   05203 Viral carcinogenesis
    119257947 (CASP3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    119257947 (CASP3)
   05222 Small cell lung cancer
    119257947 (CASP3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    119257947 (CASP3)
   05161 Hepatitis B
    119257947 (CASP3)
   05160 Hepatitis C
    119257947 (CASP3)
   05164 Influenza A
    119257947 (CASP3)
   05162 Measles
    119257947 (CASP3)
   05168 Herpes simplex virus 1 infection
    119257947 (CASP3)
   05163 Human cytomegalovirus infection
    119257947 (CASP3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119257947 (CASP3)
   05169 Epstein-Barr virus infection
    119257947 (CASP3)
   05165 Human papillomavirus infection
    119257947 (CASP3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    119257947 (CASP3)
   05133 Pertussis
    119257947 (CASP3)
   05134 Legionellosis
    119257947 (CASP3)
   05152 Tuberculosis
    119257947 (CASP3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    119257947 (CASP3)
   05145 Toxoplasmosis
    119257947 (CASP3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    119257947 (CASP3)
   05012 Parkinson disease
    119257947 (CASP3)
   05014 Amyotrophic lateral sclerosis
    119257947 (CASP3)
   05016 Huntington disease
    119257947 (CASP3)
   05020 Prion disease
    119257947 (CASP3)
   05022 Pathways of neurodegeneration - multiple diseases
    119257947 (CASP3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119257947 (CASP3)
   05416 Viral myocarditis
    119257947 (CASP3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    119257947 (CASP3)
   04932 Non-alcoholic fatty liver disease
    119257947 (CASP3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    119257947 (CASP3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    119257947 (CASP3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:tod01002]
    119257947 (CASP3)
Enzymes [BR:tod01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.56  caspase-3
     119257947 (CASP3)
Peptidases and inhibitors [BR:tod01002]
 Cysteine peptidases
  Family C14: caspase family
   119257947 (CASP3)
SSDB
Motif
Pfam: Peptidase_C14
Other DBs
NCBI-GeneID: 119257947
NCBI-ProteinID: XP_037382298
LinkDB
Position
Unknown
AA seq 277 aa
MEYSENSVDSKSIKNSEMKIFHGSKSMDSGISLDNSYKMDYPEMGLCVIINNKNFLGSTG
MACRSGTDEDAAKLRETFLNLKYEVQNKNDLTCKEIKELMYDVSKEDHSKRSSFVCVLLS
HGDEGIIYGTDGPIDLKILTGYFKGENCRSLTGKPKLFIIQACRGTDLDSGIETDSGTDD
DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKLYAHKLELMHILTRVN
QKVAREYESFSLNSTFHAKKQIPCIVSMLTKELYFYH
NT seq 834 nt   +upstreamnt  +downstreamnt
atggagtactctgaaaactcagtggattcaaaatccattaaaaattcagaaatgaagatc
ttccatggaagcaaatcaatggactctgggatatccttggacaatagttacaaaatggat
tatcctgaaatgggtttatgtgtaataattaataataagaactttcttgggagtactgga
atggcatgtcggtctggtacagatgaagatgcagcaaagctcagggaaacattcctgaac
ttgaaatatgaagtccagaataaaaatgatcttacatgtaaagaaattaaagaattgatg
tacgatgtttctaaagaagatcacagcaagaggagcagttttgtttgtgtgcttctgagc
catggtgacgaaggaataatctatggaacagatggccctattgacctgaaaatactgaca
ggttatttcaaaggggaaaactgtagaagtctaaccggaaaacccaagcttttcattatt
caggcttgccgaggtacagatctggactctggtattgagactgacagtggtactgatgat
gacatggcatgtcacaaaataccagttgaagcagacttcttgtatgcatactctacagcg
cctggttactactcctggcgaaattcaaaggatgggtcctggttcatccagtcactttgt
gcaatgctgaaactgtacgctcacaaacttgaactcatgcacattcttactcgggttaac
caaaaggtagcgagagaatatgagtccttttccttgaactccacttttcatgcaaagaag
cagattccatgtattgtgtccatgctcacaaaagaactgtatttttatcattaa

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